Bibliography : Musculoskeletal disorders

Matching entries: 0
settings...
AuthorTitleYearJournal/ProceedingsReftypeDOI/URL
Balasubramanya B, Nisha C, Ramesh N, Joseph B Staff working in ancillary departments at a tertiary care hospital in Bengaluru, Karnataka, India: How healthy are they? 2016 Indian J Occup Environ Med.  article DOI  
Abstract: BACKGROUND:
Ancillary health services are those supplemental services other than room, board, and medical/nursing services provided to hospital patients in the course of care. Ancillary department staff forms an integral part in the smooth functioning of a hospital. There is a need to focus on the health of these individuals to ensure their well-being and in turn, productivity at the workplace.
OBJECTIVE:
To study the morbidity profile of the staff working at ancillary departments of a tertiary care hospital in Bengaluru, Karnataka, India.
MATERIALS AND METHODS:
We conducted our study in a 1,200-bedded tertiary care hospital in Bengaluru, Karnataka, India. Annual medical checkup (AMC) for all the staff working at the ancillary departments has been started in recent years and is provided free of cost and during working hours. A total of 150 employees from ancillary departments underwent AMC in the year 2013. Data were analyzed using Statistical Package for the Social Sciences (SPSS) version 20.0. Spearman's correlation and Chi-square test were used.
RESULTS:
Of the 150 employees, the majority was male (72%); the mean age was 38 ± 11 years. The most common morbidities were diabetes mellitus (11%), hypertension (10.6%), musculoskeletal disorders (9.3%), surgical problems (8.6%, hemorrhoids, varicose veins), and dental caries (6.6%). On stool microscopy, 12% of the dietary workers showed ova/cyst. There was a significant positive correlation between age and the number of chronic morbidities (P < 0.01).
CONCLUSION:
Lifestyle disorders such as diabetes mellitus and hypertension were the major morbidities among the staff in the ancillary departments of the hospital. We ensured regular follow-up, adherence to medication, and lifestyle modifications in terms of diet and exercise.
BibTeX:
@article{BalasubramanyaB12016,
  author = {Balasubramanya B1, Nisha C1, Ramesh N1, Joseph B1.},
  title = {Staff working in ancillary departments at a tertiary care hospital in Bengaluru, Karnataka, India: How healthy are they?},
  journal = {Indian J Occup Environ Med.},
  year = {2016},
  doi = {http://dx.doi.org/10.4103/0019-5278.183844}
}
Batham C, Yasobant S A risk assessment study on work-related musculoskeletal disorders among dentists in Bhopal, India. 2016 Indian J Dent Res.  article DOI  
Abstract: BACKGROUND:
Work-related musculoskeletal disorders (WMSDs) are responsible for morbidity in many working populations, which are of multifactorial in origin and of global concern due to industrialization. Dentists as one of the health-care professionals are prone to develop these WMSDs. The study aims to determine the prevalence of WMSDs among dentists in Bhopal region and explores the various risk factors for the development of MSDs and WMSDs.
MATERIALS AND METHODS:
This proposed study is a cross-sectional study conducted among dentists of two randomly selected dental colleges of Bhopal, India. A structured questionnaire was used to collect the demographic information, occupational history, risk factors, and ergonomic awareness with job task details. Prevalidated standardized tools such as quick exposure check list, rapid entire body assessment score sheet, and Nordic Musculoskeletal Questionnaire were also used. Data were entered in MS-Excel and analyzed through SPSS version 18.
RESULTS:
More than 92% of the participants reported pain and discomfort in at least one part of their body. The major affected body part is neck, followed by the lower back and wrist. More than half of the orthodontists and oral surgeons reported that their MSDs are work-related origin. Pearson's correlation test indicated that there is a positive correlation between the current exposure and risk (r = 0.613). Multivariate regression analysis found that younger participants, male (OR = 4.1), involved physical activity (OR = 1.04), dentists not taught about ergonomics in their dental school (OR = 1.69) or never attended any workshops (OR = 1.38), who reported task involving sustained muscle contraction (OR = 1.12) or task with repetitive movements (OR = 1.11) are the major risk factors for the development of MSDs among the dentists.
CONCLUSION:
This risk assessment study found that there is a high prevalence of MSDs and WMSDs among dentists. Ergonomic awareness and health promotion need to be integrated with the professional practice for dentists.
BibTeX:
@article{BathamC12016,
  author = {Batham C1, Yasobant S1.},
  title = {A risk assessment study on work-related musculoskeletal disorders among dentists in Bhopal, India.},
  journal = {Indian J Dent Res.},
  year = {2016},
  doi = {http://dx.doi.org/10.4103/0970-9290.186243}
}
Bhattacharyya T, Jha S, Wang H, Kastner DL, Remmers EF Hypophosphatasia and the risk of atypical femur fractures: a case-control study. 2016 BMC Musculoskelet Disord.  article DOI  
Abstract: BACKGROUND:
Case reports have linked adult hypophosphatasia as a possible cause of atypical femur fractures (AFF) associated with bisphosphonate use. Adult hypophosphatasia is an asymptomatic genetic condition which results in low alkaline phosphatase and elevated pyridoxal phosphate. We conducted a case-control study to assess the role of hypophosphatasia and atypical femur fracture.
METHODS:
We recruited 13 control patients who took long term bisphosphonates without complication and 10 patients who sustained atypical femur fractures (mean bisphosphonate use, 9 years both cohorts). Patients underwent clinical exam and measurement of alkaline phosphatase and pyridoxal phosphate (PLP) levels. In addition, DNA was extracted and the ALPL gene was sequenced in both cohorts.
RESULTS:
Low alkaline phosphatase levels (<55 U/L) were seen in 5/10 AFF patients and 5/13 control patients. Two control patients demonstrated low alkaline phosphatase levels and elevated PLP. The alkaline phosphatase (ALPL) gene exons and intron splice sites were sequenced in the atypical femur fracture and control cohorts and no coding mutations were identified in any subjects. Atypical femur fracture patients demonstrated more varus hip alignment (p?CONCLUSIONS:
We found no evidence of hypophosphatasia as a risk factor for atypical femur fractures. Laboratory findings of mildly low alkaline phosphatase activity were equally common in atypical and control cohorts and may be due to long term bisphosphonate use.
BibTeX:
@article{BhattacharyyaT12016,
  author = {Bhattacharyya T1, Jha S2, Wang H3, Kastner DL3, Remmers EF3.},
  title = {Hypophosphatasia and the risk of atypical femur fractures: a case-control study.},
  journal = {BMC Musculoskelet Disord.},
  year = {2016},
  doi = {http://dx.doi.org/10.1186/s12891-016-1191-8}
}
Karnik AS, Karnik A, Joshi A Ultrasound Examination of Pediatric Musculoskeletal Diseases and Neonatal Spine. 2016 Indian J Pediatr.  article DOI  
Abstract: Ultrasound (US) is a simple, non-invasive imaging modality which allows high-resolution imaging of the musculoskeletal (MSK) system. Its increasing popularity in pediatrics is due to the fact that it does not involve radiation, has an ability to visualize non-ossified cartilaginous and vascular structures, allows dynamic imaging and quick contralateral comparison. US is the primary imaging modality in some pediatric MSK conditions like infant hip in developmental dysplasia (DDH), hip joint effusion, epiphyseal trauma and evaluation of the neonatal spine. US is the modality of choice in infants with DDH, both in the initial evaluation and post-treatment follow-up. US has a sensitivity equivalent to MRI in evaluation of the neonatal spine in experienced hands and is a good screening modality in neonates with suspected occult neural tube defects. In other MSK applications, it is often used for the initial diagnosis or in addition to other imaging modalities. In trauma and infections, US can often detect early and subtle soft tissue abnormalities and a quick comparison with the contralateral side aids in diagnoses. Dynamic imaging is crucial in evaluating congenital instabilities and dislocations, soft tissue and ligamentous injuries, epiphyseal injuries and fracture separations. High-resolution imaging along with color Doppler (CD) is useful in the characterization of soft tissue masses. This article reviews the applications of US in pediatric MSK with emphasis on conditions where it is a primary modality. Limitations of US include inability to penetrate bone, hence, limited diagnosis of intraosseous pathology and operator dependency.
BibTeX:
@article{KarnikAS12016,
  author = {Karnik AS1, Karnik A2,3, Joshi A4.},
  title = {Ultrasound Examination of Pediatric Musculoskeletal Diseases and Neonatal Spine.},
  journal = {Indian J Pediatr.},
  year = {2016},
  doi = {http://dx.doi.org/10.1007/s12098-015-1957-2}
}
Malik SS, Ahmed U, Malik SS Alternative use of the bradford sling as a dorsiwedge. 2016 Ann R Coll Surg Engl  article DOI  
BibTeX:
@article{MalikSS12016,
  author = {Malik SS1, Ahmed U1, Malik SS2.},
  title = {Alternative use of the bradford sling as a dorsiwedge.},
  journal = {Ann R Coll Surg Engl},
  year = {2016},
  doi = {http://dx.doi.org/10.1308/rcsann.2016.0010}
}
Nagavarapu S, Lavender SA, Marras WS Spine loading during the application and removal of lifting slings: the effects of patient weight, bed height and work method. 2016 Ergonomics  article  
Abstract: The biomechanical loading on the lumbar spine was assessed as 12 female nurses applied and removed slings under two patients of differing weights (54 and 100 kg), using two work methods, and while working at three bed heights (56, 71, 93 cm). Three-dimensional spine loads at the L2/L3, L3/L4, L4/L5 and L5/S1 disc levels were measured using a validated EMG-assisted biomechanical model. Anterior/posterior (A/P) shear loading at the L5/S1 level consistently exceeded the tolerance threshold limit for disc failure. The peak compression values exceeded the 3400 N tolerance threshold for several participants when placing the sling under the 100-kg patient. In general, working from both sides of the bed generated slightly higher A/P shear loading than the one-sided method. Raising the bed significantly decreased compression and A/P shear forces. Therefore, raising the bed to at least the nurse's knuckle height is recommended when applying and removing patient slings. Practitioners Summary: We investigated the spine loading associated with placing and removing slings used for the mechanised lifting of patients. Peak compression and anterior shear forces exceeded recognised thresholds when placing slings underneath heavier patients. Raising the bed to at least knuckle level helps mitigate these spinal loads.
BibTeX:
@article{NagavarapuS12016,
  author = {Nagavarapu S1, Lavender SA1,2, Marras WS1,3.},
  title = {Spine loading during the application and removal of lifting slings: the effects of patient weight, bed height and work method.},
  journal = {Ergonomics},
  year = {2016}
}
Nair PM, Khawale PG Role of therapeutic fasting in women's health: An overview 2016 J Midlife Health.  article DOI  
Abstract: Fasting is a therapeutic tool practiced since millennia by different cultures and medical systems heterogeneously. PubMed and Google Scholar search engines were searched using the keywords "fasting," "intermittent fasting," "calorie restriction," "women's health," "women's disorders," "fasting and aging," and "fasting and health." All the animal and human studies which address women's health and disorders were included in the review. Fasting has shown to improve the reproductive and mental health. It also prevents as well as ameliorates cancers and musculoskeletal disorders which are common in middle-aged and elderly women. The present studies available have limitations such as majority of the studies are preclinical studies and human studies are with lesser sample size. Future studies should address this gap by designing medically supervised fasting techniques to extract better evidence. Nevertheless, fasting can be prescribed as a safe medical intervention as well as a lifestyle regimen which can improve women's health in many folds
BibTeX:
@article{NairPM12016,
  author = {Nair PM1, Khawale PG1.},
  title = {Role of therapeutic fasting in women's health: An overview},
  journal = {J Midlife Health.},
  year = {2016},
  doi = {http://dx.doi.org/10.4103/0976-7800.185325}
}
Raithatha AS, Mishra DG Musculoskeletal Disorders and Perceived Work Demands among Female Nurses at a Tertiary Care Hospital in India. 2016 Int J Chronic Dis.  article  
Abstract: Introduction. Musculoskeletal disorders (MSD) are common among nurses and can affect patient outcomes. There is a dearth of literature on MSD among Indian nurses. The study objective was to measure prevalence of MSD and their association with perceived work demands and sociodemographic variables among female nurses at a tertiary care hospital in rural India. Methods. A cross-sectional study was undertaken in 2013 through interviewer administered questionnaires which comprised three parts: sociodemographic data, modified Nordic questionnaire, and perceived physical and psychological work demands. Results. 296 nurses with a mean age of 30.4 years participated. Prevalence of any MSD in the last seven days was 60.5% with low back pain being the most common and elbow pain the least common. Occurrence of any MSD was associated with age, number of children, working hours at home, BMI, and total work experience. High perceived physical demands score was associated with lower back (OR: 3.06) and knee pain (OR: 7.73). Conclusion. Prevalence of MSD was high and occurrence of lower back and knee MSD was associated with perceived physical demands. This information should be used as a benchmark and guiding tool for designing work place interventions to improve working conditions and health of nurses.
BibTeX:
@article{RaithathaAS12016,
  author = {Raithatha AS1, Mishra DG1.},
  title = {Musculoskeletal Disorders and Perceived Work Demands among Female Nurses at a Tertiary Care Hospital in India.},
  journal = {Int J Chronic Dis.},
  year = {2016}
}
Rajeswari SR, Gowda TM, Kumar TA, Arya K, Mehta DS Assessment of interns and postgraduate dental student's knowledge regarding equipment ergonomics. 2016 Indian J Dent Res  article  
Abstract: CONTEXT:
The substantial knowledge concerning ergonomics and its practical application is vital for forestalling musculoskeletal disorders. The role of equipment ergonomics (EE) in preventing these work-related ailments is significantly noteworthy.
AIM:
The aim of the study was to assess the prevailing perception of postgraduates (PGs) and interns regarding EE and preparing the Indian dental workforce for the challenges of India's growing economy and population.
SETTINGS AND DESIGN:
Authors conducted a cross-sectional survey between December 2013 and February 2014 amidst the interns and PG dental students of Davangere city, Karnataka, India.
SUBJECTS AND METHODS:
The data were collected using 21-item custom designed proforma, comprising of questions evaluating student's basic knowledge about EE.
STATISTICAL ANALYSIS USED:
Statistical analysis was done using Chi-square test in each group (PGs and interns) and Mann-Whitney test was implemented for comparison between both groups.
RESULTS:
Of 358 subjects surveyed, 48% PGs and 52% interns affirmed that they came across EE only through this survey. In addition, 91.18% of PGs and 90.59% interns believed that the accentuation on EE is less in the current dental curriculum.
CONCLUSIONS:
Comprehensive understanding and practical application of EE among the participants was found to be lacking. The importance of microbreaks and chair side exercises should be emphasized and training should be initiated at an early stage before improper postural habits develop.
BibTeX:
@article{RajeswariSR12016,
  author = {Rajeswari SR1, Gowda TM1, Kumar TA1, Arya K1, Mehta DS1.},
  title = {Assessment of interns and postgraduate dental student's knowledge regarding equipment ergonomics.},
  journal = {Indian J Dent Res},
  year = {2016}
}
Sarkar K, Dev S, Das T, Chakrabarty S, Gangopadhyay S Examination of postures and frequency of musculoskeletal disorders among manual workers in Calcutta, India. 2016 Int J Occup Environ Health., pp. 151-8  article  
Abstract: BACKGROUND:
Manual material handling (MMH) activities require workers to adopt various awkward postures leading to the development of musculoskeletal disorders (MSD).
OBJECTIVES:
To investigate the postures adopted during heavy load handling and the frequency of MSDs among MMH workers in Calcutta, India.
METHODS:
We conducted a cross-sectional study with 100 MMH workers. MSD frequency was assessed via the Standardized Nordic Questionnaire. The Ovako Working Posture Assessment System (OWAS) was used to analyze working posture. We used logistic regression to predict MSD risk factors.
RESULTS:
Ninety five percent of workers reported a MSD in at least one body part in the past 12 months. According to OWAS results, 83% of the analysed work postures require immediate corrective measures for worker safety. The most harmful posture was carrying a heavy load overhead. Carrying more than 120 kg increased the odds of low back and neck pain by 4.527 and 4.555, respectively.
CONCLUSIONS:
This sample had a high frequency of reported MSDs, likely attributed to physiologically strenuous occupational activities repeated on average of 30-40 times daily. Ergonomic interventions, such as the use of handcarts, and occupational training are urgently needed.
BibTeX:
@article{SarkarK12016,
  author = {Sarkar K1, Dev S1, Das T2, Chakrabarty S1, Gangopadhyay S1.},
  title = {Examination of postures and frequency of musculoskeletal disorders among manual workers in Calcutta, India.},
  journal = {Int J Occup Environ Health.},
  year = {2016},
  pages = {151-8}
}
Sarkar K, Dev S, Das T, Chakrabarty S, Gangopadhyay S Examination of postures and frequency of musculoskeletal disorders among manual workers in Calcutta, India. 2016 Int J Occup Environ Health  article  
Abstract: BACKGROUND:
Manual material handling (MMH) activities require workers to adopt various awkward postures leading to the development of musculoskeletal disorders (MSD).
OBJECTIVES:
To investigate the postures adopted during heavy load handling and the frequency of MSDs among MMH workers in Calcutta, India.
METHODS:
We conducted a cross-sectional study with 100 MMH workers. MSD frequency was assessed via the Standardized Nordic Questionnaire. The Ovako Working Posture Assessment System (OWAS) was used to analyze working posture. We used logistic regression to predict MSD risk factors.
RESULTS:
Ninety five percent of workers reported a MSD in at least one body part in the past 12 months. According to OWAS results, 83% of the analysed work postures require immediate corrective measures for worker safety. The most harmful posture was carrying a heavy load overhead. Carrying more than 120 kg increased the odds of low back and neck pain by 4.527 and 4.555, respectively.
CONCLUSIONS:
This sample had a high frequency of reported MSDs, likely attributed to physiologically strenuous occupational activities repeated on average of 30-40 times daily. Ergonomic interventions, such as the use of handcarts, and occupational training are urgently needed.
BibTeX:
@article{SarkarK12016a,
  author = {Sarkar K1, Dev S1, Das T2, Chakrabarty S1, Gangopadhyay S},
  title = {Examination of postures and frequency of musculoskeletal disorders among manual workers in Calcutta, India.},
  journal = {Int J Occup Environ Health},
  year = {2016}
}
Singh AG, Singh S, Matteson EL Rate, risk factors and causes of mortality in patients with Sjögren's syndrome: a systematic review and meta-analysis of cohort studies. 2016 Rheumatology (Oxford)., pp. 450-60  article DOI  
Abstract: OBJECTIVES:
There is conflicting evidence regarding prognosis in patients with primary SS (pSS). The aim of this study was to estimate the rate, risk factors and causes of mortality in patients with pSS through a systematic review and meta-analysis.
METHODS:
Through a systematic review of multiple databases through October 2014, we identified cohort studies reporting relative risk (compared with standardized population), risk factors and causes of mortality in patients with pSS. We estimated summary risk ratios (RRs) with 95% CIs using random effects model.
RESULTS:
We identified 10 studies with 7888 patients (91% females) with pSS, of whom 682 patients died over a median average follow-up of 9 years. The pooled standardized mortality ratio in patients with pSS was 1.38 (95% CI 0.94, 2.01). Leading causes of mortality were cardiovascular diseases, solid-organ and lymphoid malignancies and infections; however, it is unclear whether these observed causes were overrepresented in patients with pSS as compared with the general population. Risk factors associated with increased mortality were advanced age at diagnosis [RR 1.09 (95% CI 1.07, 1.12)], male sex [RR 2.18 (95% CI 1.45, 3.27)], parotid enlargement [RR 1.81 (95% CI 1.02, 3.21)], abnormal parotid scintigraphy [RR 2.96 (95% CI 1.36, 6.45)], extraglandular involvement [RR 1.77 (95% CI 1.06, 2.95)], vasculitis [RR 7.27 (95% CI 2.70, 19.57)], anti-SSB positivity [RR 1.45 (95% CI 1.03, 2.04)], low C3 [RR 2.14 (95% CI 1.38, 3.32)] and C4 [RR 3.08 (95% CI 2.14, 4.42)] and cryoglobulinaemia [RR 2.62 (95% CI 1.77, 3.90)].
BibTeX:
@article{SinghAG12016,
  author = {Singh AG1, Singh S2, Matteson EL3.},
  title = {Rate, risk factors and causes of mortality in patients with Sjögren's syndrome: a systematic review and meta-analysis of cohort studies.},
  journal = {Rheumatology (Oxford).},
  year = {2016},
  pages = {450-60},
  doi = {http://dx.doi.org/10.1093/rheumatology/kev354}
}
Singh N, Johnstone DB, Martin KA, Tempera I, Kaplan MJ, Denny MF Alterations in nuclear structure promote lupus autoimmunity in a mouse model. 2016 Dis Model Mech  article DOI  
Abstract: Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by the development of autoantibodies that recognize components of the cell nucleus. The vast majority of lupus research has focused on either the contributions of immune cell dysfunction or the genetics of the disease. Because granulocytes isolated from human SLE patients had alterations in neutrophil nuclear morphology that resembled the Pelger-Huet anomaly, and had prominent mis-splicing of mRNA encoding the nuclear membrane protein lamin B receptor (LBR), consistent with their Pelger-Huet-like nuclear morphology, we used a novel mouse model system to test the hypothesis that a disruption in the structure of the nucleus itself also contributes to the development of lupus autoimmunity. The lupus-prone mouse strain New Zealand White (NZW) was crossed with c57Bl/6 mice harboring a heterozygous autosomal dominant mutation in Lbr (B6.Lbr(ic/+)), and the (NZW×B6.Lbr(ic))F1 offspring were evaluated for induction of lupus autoimmunity. Only female (NZW×B6.Lbr(ic))F1 mice developed lupus autoimmunity, which included splenomegaly, kidney damage and autoantibodies. Kidney damage was accompanied by immune complex deposition, and perivascular and tubule infiltration of mononuclear cells. The titers of anti-chromatin antibodies exceeded those of aged female MRL-Fas(lpr) mice, and were predominantly of the IgG2 subclasses. The anti-nuclear antibody staining profile of female (NZW×B6.Lbr(ic))F1 sera was complex, and consisted of an anti-nuclear membrane reactivity that colocalized with the A-type lamina, in combination with a homogeneous pattern that was related to the recognition of histones with covalent modifications that are associated with gene activation. An anti-neutrophil IgM recognizing calreticulin, but not myeloperoxidase (MPO) or proteinase 3 (PR3), was also identified. Thus, alterations in nuclear structure contribute to lupus autoimmunity when expressed in the context of a lupus-prone genetic background, suggesting a mechanism for the development of lupus autoimmunity in genetically predisposed individuals that is induced by the disruption of nuclear architecture.
BibTeX:
@article{SinghN12016,
  author = {Singh N1, Johnstone DB2, Martin KA3, Tempera I3, Kaplan MJ4, Denny MF5.},
  title = {Alterations in nuclear structure promote lupus autoimmunity in a mouse model.},
  journal = {Dis Model Mech},
  year = {2016},
  doi = {http://dx.doi.org/10.1242/dmm.024851}
}
Aggarwal H, Kumar P Orbital retinoblastoma: Prosthetic frontier. 2015 J Cancer Res Ther.  article  
BibTeX:
@article{AggarwalH12015,
  author = {Aggarwal H1, Kumar P.},
  title = {Orbital retinoblastoma: Prosthetic frontier.},
  journal = {J Cancer Res Ther.},
  year = {2015}
}
Chandra SR, Issac TG, Gayathri N, Gupta N, Abbas MM A typical case of myoclonic epilepsy with ragged red fibers (MERRF) and the lessons learned 2015 J Postgrad Med.  article  
Abstract: Mitochondrial diseases have a special predilection to involve the brain in view of its high metabolic demand and the tendency for the formation of excitatory neurotransmitters when there is deficiency of intracellular ATP. These diseases have a great phenotypic variation and need a high degree of suspicion. However, some specific syndromes are well defined, both genotypically and phenotypically. Some of the drugs are potentially fatal mitochondrial poisons and an insight into that may be lifesaving as well as prevent serious morbidities.We report a typical case of myoclonic epilepsy with ragged red fibers (MERRF) with classical phenotype and genotype. There was rapid multiaxial deterioration with the introduction of sodium valproate which partly reversed on introducing mitochondrial cocktail and withdrawal of the offending drug.Sodium valproate, phenobarbitone, chloramphenicol and many anti-viral agents are mitochondrial poisons that increase the morbidity and mortality in patients with mitochondrial disease. More harm to the patient can be avoided with insight into this information.
BibTeX:
@article{ChandraSR12015,
  author = {Chandra SR1, Issac TG, Gayathri N, Gupta N, Abbas MM},
  title = {A typical case of myoclonic epilepsy with ragged red fibers (MERRF) and the lessons learned},
  journal = {J Postgrad Med.},
  year = {2015}
}
Kapoor SR, McGrath CM, Fitzpatrick MA, Young SP Metabolomics in rheumatology. 2015 Rheumatology (Oxford)., pp. 2124-5  article DOI  
BibTeX:
@article{KapoorSR12015,
  author = {Kapoor SR1, McGrath CM1, Fitzpatrick MA1, Young SP},
  title = {Metabolomics in rheumatology.},
  journal = {Rheumatology (Oxford).},
  year = {2015},
  pages = {2124-5},
  doi = {http://dx.doi.org/10.1093/rheumatology/kev334}
}
Kumar D, Gupta A, Sharma VP, Yadav G, Singh A, Verma AK Pentazocine-induced contractures: Dilemma in management. 2015 Indian J Pharmacol.  article  
BibTeX:
@article{KumarD12015,
  author = {Kumar D1, Gupta A1, Sharma VP1, Yadav G1, Singh A2, Verma AK3.},
  title = {Pentazocine-induced contractures: Dilemma in management.},
  journal = {Indian J Pharmacol.},
  year = {2015}
}
Pandey SN, Kesari A, Yokota T, Pandey GS Muscular Dystrophy: Disease Mechanisms and Therapies. 2015 Biomed Res Int.  article  
BibTeX:
@article{PandeySN12015,
  author = {Pandey SN1, Kesari A2, Yokota T3, Pandey GS4.},
  title = {Muscular Dystrophy: Disease Mechanisms and Therapies.},
  journal = {Biomed Res Int.},
  year = {2015}
}
Chandra PS In Reply: Different Facets in Management of Congenital Atlantoaxial Dislocation and Basilar Invagination. 2015 Neurosurgery.  article DOI  
BibTeX:
@article{PS1.2015,
  author = {Chandra PS1.},
  title = {In Reply: Different Facets in Management of Congenital Atlantoaxial Dislocation and Basilar Invagination.},
  journal = {Neurosurgery.},
  year = {2015},
  doi = {http://dx.doi.org/10.1227/NEU.0000000000000959}
}
Chandra PS In Reply: Different Facets in Management of Congenital Atlantoaxial Dislocation and Basilar Invagination. 2015 Neurosurgery.  article  
BibTeX:
@article{PS1.2015a,
  author = {Chandra PS1.},
  title = {In Reply: Different Facets in Management of Congenital Atlantoaxial Dislocation and Basilar Invagination.},
  journal = {Neurosurgery.},
  year = {2015}
}
Prasad S Ectopia lentis in Marfan's syndrome causing positional visual symptoms. 2015 Pract Neurol., pp. 484  article DOI  
BibTeX:
@article{S.2015,
  author = {Prasad S.},
  title = {Ectopia lentis in Marfan's syndrome causing positional visual symptoms.},
  journal = {Pract Neurol.},
  year = {2015},
  pages = {484},
  doi = {http://dx.doi.org/10.1136/practneurol-2014-001078}
}
Prasad S Ectopia lentis in Marfan's syndrome causing positional visual symptoms. 2015 Pract Neurol., pp. 484  article DOI  
BibTeX:
@article{S.2015a,
  author = {Prasad S.},
  title = {Ectopia lentis in Marfan's syndrome causing positional visual symptoms.},
  journal = {Pract Neurol.},
  year = {2015},
  pages = {484},
  doi = {http://dx.doi.org/10.1136/practneurol-2014-001078}
}
Satpathy S, Patra A, Ahirwar B Experimental techniques for screening of antiosteoporotic activity in postmenopausal osteoporosis 2015 J Complement Integr Med., pp. 251-66  article  
Abstract: Postmenopausal osteoporosis, a silent epidemic, has become a major health hazard, afflicting about 50% of postmenopausal women worldwide and is thought to be a disease with one of the highest incidences in senile people. It is a chronic, progressive condition associated with micro-architectural deterioration of bone tissue that results in low bone mass, decreased bone strength that predisposes to an increased risk of fracture. Women are more likely to develop osteoporosis than men due to reduction in estrogen during menopause which leads to decline in bone formation and increase in bone resorption activity. Estrogen is able to suppress the production of proinflammatory cytokines like interleukin (IL)-1, IL-6, IL-7 and tumor necrosis factor (TNF-?). This is why these cytokines are elevated in postmenopausal women. In this review article we have made an attempt to collate the various methods and parameters most frequently used for screening of antiosteoporotic activity in postmenopausal osteoporosis. Pertaining to ovariectomized animal model, this is the most appropriate model for studying the efficacy of different drugs to prevent bone loss in postmenopausal osteoporosis.
BibTeX:
@article{SatpathyS2015,
  author = {Satpathy S, Patra A, Ahirwar B.},
  title = {Experimental techniques for screening of antiosteoporotic activity in postmenopausal osteoporosis},
  journal = {J Complement Integr Med.},
  year = {2015},
  pages = {251-66}
}
Shamji MF, Mroz T, Hsu W, Chutkan N Management of Degenerative Lumbar Spinal Stenosis in the Elderly. 2015 Neurosurgery.  article DOI  
Abstract: BACKGROUND:
Lumbar spinal stenosis can cause symptomatic neurogenic claudication alongside radicular pain and weakness. In appropriately selected patients, surgical intervention has been demonstrated to provide for improvement in pain, disability, and quality of life. This systematic review sought to define the utility and safety of such decompression with or without arthrodesis in the management of symptomatic lumbar spinal stenosis for elderly patients older than 65 years of age.
METHODS:
A systematic review was conducted using MEDLINE for literature published through December 2014. The first question focused on the effectiveness of lumbar spinal surgery for symptomatic lumbar spinal stenosis in elderly patients (over age 65 y). The second question focused on safety of surgical intervention on this elderly population with emphasis on perioperative complication rates.
RESULTS:
Review of 11 studies reveals that the majority of elderly patients exhibit significant symptomatic improvement, with overall benefits observed for pain (change visual analog scale 4.4 points) and disability (change Oswestry Disability Index 23 points). Review of 11 studies reveals that perioperative complications were infrequent and acceptable with pooled estimates of mortality (0.5%), inadvertent durotomy (5%), and wound infection (2%). Outcomes seem less favorable with greater complication rates among patients with diabetes or obesity.
CONCLUSION:
Based on largely low-quality, retrospective evidence, we recommend that elderly patients should not be excluded from surgical intervention for symptomatic lumbar spinal stenosis.
BibTeX:
@article{ShamjiMF12015,
  author = {Shamji MF1, Mroz T, Hsu W, Chutkan N.},
  title = {Management of Degenerative Lumbar Spinal Stenosis in the Elderly.},
  journal = {Neurosurgery.},
  year = {2015},
  doi = {http://dx.doi.org/10.1227/NEU.0000000000000943}
}
Shetty S, Kapoor N, Jeyaraj V, Roy AC, Paul TV Visual Vignette. 2015 Endocr Pract., pp. 975  article  
BibTeX:
@article{ShettyS12015,
  author = {Shetty S1, Kapoor N1, Jeyaraj V2, Roy AC3, Paul TV1.},
  title = {Visual Vignette.},
  journal = {Endocr Pract.},
  year = {2015},
  pages = {975}
}
Singh S, Chokhandre P Assessing the impact of waste picking on musculoskeletal disorders among waste pickers in Mumbai, India: a cross-sectional study. 2015 BMJ Open., pp. 5  article  
Abstract: OBJECTIVE:
To assess the prevalence of musculoskeletal disorders (MSDs) as well as the impact of the occupation of waste picking on complaints of MSDs among waste pickers. The study attempts to understand the risk factors for MSDs in various areas of the body.
DESIGN:
A cross-sectional household survey was conducted using a case-control design. The survey instrument for measuring musculoskeletal symptoms was adopted from a standardised Nordic questionnaire. The impact of the occupation of waste picking on MSDs was analysed using the propensity score matching (PSM) method.
PARTICIPANTS:
The study population consisted of waste pickers (n=200) who had been working for at least a year and a control group (n=213) selected from among or living close to the same communities.
RESULTS:
The 12-month prevalence of MSDs was higher among waste pickers (79%) compared to controls (55%) particularly in the lower back (54-36%), knee (48-35%), upper back (40-21%) and shoulder (32-12%). Similar patterns were observed in the 12-month prevalence of MSDs which prevented normal activity inside and outside the home, particularly for the lower back (36-21%), shoulder (21-7%) and upper back (25-12%) for waste pickers and controls. Analysis of the impact of waste picking on complaints of MSDs suggests that the occupation of waste picking raises the risk of MSDs particularly in the shoulder, lower and upper back. Older age and longer duration of work are significant risk factors for MSDs.
CONCLUSIONS:
The findings suggest a relatively higher prevalence of MSDs among waste pickers, particularly in the lower and upper back and shoulder, compared to controls. Preventive measures and treatment to minimise the burden of MSDs among waste pickers are strongly recommended.
Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.
BibTeX:
@article{SinghS12015,
  author = {Singh S1, Chokhandre P2.},
  title = {Assessing the impact of waste picking on musculoskeletal disorders among waste pickers in Mumbai, India: a cross-sectional study.},
  journal = {BMJ Open.},
  year = {2015},
  pages = {5}
}
Vohra R, Accorsi A, Kumar A, Walter G, Girgenrath M Magnetic Resonance Imaging Is Sensitive to Pathological Amelioration in a Model for Laminin-Deficient Congenital Muscular Dystrophy (MDC1A). 2015 PLoS One.  article DOI  
Abstract: PURPOSE:
To elucidate the reliability of MRI as a non-invasive tool for assessing in vivo muscle health and pathological amelioration in response to Losartan (Angiotensin II Type 1 receptor blocker) in DyW mice (mouse model for Laminin-deficient Congenital Muscular Dystrophy Type 1A).
METHODS:
Multiparametric MR quantifications along with histological/biochemical analyses were utilized to measure muscle volume and composition in untreated and Losartan-treated 7-week old DyW mice.
RESULTS:
MRI shows that DyW mice have significantly less hind limb muscle volume and areas of hyperintensity that are absent in WT muscle. DyW mice also have significantly elevated muscle levels (suggestive of inflammation and edema). Muscle T2 returned to WT levels in response to Losartan treatment. When considering only muscle pixels without T2 elevation, DyW T2 levels are significantly lower than WT (suggestive of fibrosis) whereas Losartan-treated animals do not demonstrate this decrease in muscle T2. MRI measurements suggestive of elevated inflammation and fibrosis corroborate with increased Mac-1 positive cells as well as increased Picrosirius red staining/COL1a gene expression that is returned to WT levels in response to Losartan.
CONCLUSIONS:
MRI is sensitive to and tightly corresponds with pathological changes in DyW mice and thus is a viable and effective non-invasive tool for assessing pathological changes
BibTeX:
@article{VohraR12015,
  author = {Vohra R1, Accorsi A2, Kumar A2, Walter G1, Girgenrath M2.},
  title = {Magnetic Resonance Imaging Is Sensitive to Pathological Amelioration in a Model for Laminin-Deficient Congenital Muscular Dystrophy (MDC1A).},
  journal = {PLoS One.},
  year = {2015},
  doi = {http://dx.doi.org/10.1371/journal.pone.0138254}
}
Agarwal A, Gupta ND Comparative evaluation of decalcified freeze-dried bone allograft use alone and in combination with polylactic acid, polyglycolic acid membrane in the treatment of noncontained human periodontal infrabony defects. 2012 Quintessence Int
Vol. 43(9), pp. 761-8 
article  
Abstract: OBJECTIVE:
To compare the regenerative potential of bone graft used alone and in combination with barrier membrane in noncontained human periodontal infrabony defects.
METHOD AND MATERIALS:
Twelve patients (7 men and 5 women, 30 to 65 years of age) with moderate to severe chronic periodontitis were included in the study. A total of 16 one- or two-walled intraosseous defects were selected and randomly divided for decalcified freeze-dried bone allograft, alone (control group) or in combination with polylactic acid, polyglycolic acid barrier membrane (test group). Pocket probing depth (PPD), clinical attachment level (CAL), radiologic bone fill (RBF), and alveolar height reduction (AHR) were recorded immediately before surgery and after 3 and 6 months postoperatively. The ANOVA and Newman-Keuls post hoc tests were used for statistical analysis. A two-tailed probability value of P < .05 was considered to be statistically significant.
RESULTS:
For bone graft alone, PPD reduction was 2.00 ± 0.19 mm, CAL gain was 1.38 ± 0.18 mm, and RBF was 0.63 ± 0.26 mm: for the test group, PPD reduction was 2.75 ± 0.37 mm, CAL gain was 1.50 ± 0.27 mm, and RBF was 1.13 ± 0.23 mm. AHR for the control and test groups was 0.38 and 0.37 mm, respectively.
CONCLUSION:
These results confirmed nonsignificant clinical and radiologic differences in regenerative outcome with bone graft alone and with guided tissue regeneration in the treatment of noncontained human periodontal infrabony defects.
BibTeX:
@article{AgarwalA2012,
  author = {Agarwal A, Gupta ND.},
  title = {Comparative evaluation of decalcified freeze-dried bone allograft use alone and in combination with polylactic acid, polyglycolic acid membrane in the treatment of noncontained human periodontal infrabony defects.},
  journal = {Quintessence Int},
  year = {2012},
  volume = {43(9)},
  pages = {761-8}
}
Agarwal S, Das SK, Agarwal GG, Srivastava R, Singh GP X-ray knee as a screening tool for osteoporosis 2012 J Clin Densitom
Vol. 15(3), pp. 362-5 
article DOI  
Abstract: Cortical thickness (Cor-Th) of tibia varies considerably on X-ray knees. It was hypothesized that Cor-Th can be used for preliminary prediction of BMD. Ninety nine patients underwent a digital X-ray left knee fixed flexion PA view with an external calibration scale attached to X-ray plate and BMD by DXA using GE lunar machine (Madison, Wisconsin.). Cor-Th was measured at 5 selected levels (A,B,C,D, and E) ranging from 5-7 cm below the tibial plateau on its medial aspect. T-scores were recorded for BMD at AP spine, left forearm and left femur. Cor-Th of tibia at each level significantly correlated with each site of BMD measurement namely AP spine, left femur and left forearm. This correlation varied in the range from 0.241 to 0.426. For AP spine, it was maximum at level C (r=0.347, p<0.001) whereas for left femur and forearm sites, it was maximum at level B (r=0.426 &r=0.373 respectively, p<0.001). The correlation of Cor-Th with BMD varied with age. Above 56 years of age, Cor-Th at each level significantly correlated to BMD at each site. Medial tibial cortical thickness, 6 cm (level C) below tibial plateau can be used as preliminary predictor of patients who need a DXA scan.
BibTeX:
@article{AgarwalS2012,
  author = {Agarwal S, Das SK, Agarwal GG, Srivastava R, Singh GP.},
  title = {X-ray knee as a screening tool for osteoporosis},
  journal = {J Clin Densitom},
  year = {2012},
  volume = {15(3)},
  pages = {362-5},
  doi = {http://dx.doi.org/10.1016/j.jocd.2012.02.008}
}
Agrawal D, Mohanty BB, Sarangi R, Kumar S, Mahapatra SK, Chinara PK Study of incidence and prevalence of musculoskeletal anomalies in a tertiary care hospital of eastern India. 2014 J Clin Diagn Res
Vol. 8(5) 
article DOI  
Abstract: INTRODUCTION:
Congenital anomalies or malformations are anatomical. Structural or functional defects present at birth leads to physical and mental disabilities. With the advent of newer drugs, infectious diseaseshave taken the backseat and congenital defects have emerged as an important cause of neonatal morbidity and mortality. In India, anomalies of musculoskeletal system have been most commonly reported.
AIMS AND OBJECTIVES:
With this in view, the present study was carried out to find the incidence and types of musculoskeletal defects in a tertiary care hospital in Eastern India. Various maternal factors were also correlated and analyzed. The purpose of this communication is to report these defects so as to help doctors and parents to prevent unexpected fetal loss and better parental counseling.
MATERIALS AND METHODS:
This study was done in the Department of Obstetrics and Gynaecology in association with Department of Paediatrics of a tertiary care hospital in Odisha from for a period of 1 year. The newborns were examined within 1(st) three days of delivery for congenital malformations. The study group included all live borns along with still borns after 28 weeks of gestation or those dead babies whose weight was about 1kg. A thorough physical examination from head to toe was done to look for musculoskeletal defects within 24hrs of delivery.
OBSERVATION AND RESULTS:
Out of total 7268 babies delivered, 116 babies were found to have anomalies. Thirty two of these had musculoskeletal defects. Talipes equinovarus was the commonest anomaly observed followed by polydactyly. The ratio of male babies with musculoskeletal defects to female babies was found to be 1.28:1.The malformed babies were mainly born to term mothers (77.6%), who were mostly unbooked (62.5%) and belonged to lower or middle class. But no significant relationship could be established between these factors and defects. Most mothers were in the age group of 20-35 years and there was no history of drug addiction, smoking, trauma or irradiation that could be related to the occurrence of congenital malformations.
CONCLUSION:
It is concluded that better maternal care and improved standards of living have very little effect on the overall frequency of congenital malformations. For the better future of neonates an early recognition of correctable lesions is essential, which calls for a systematic approach to the study of musculoskeletal defects.
BibTeX:
@article{AgrawalD2014,
  author = {Agrawal D, Mohanty BB, Sarangi R, Kumar S, Mahapatra SK, Chinara PK.},
  title = {Study of incidence and prevalence of musculoskeletal anomalies in a tertiary care hospital of eastern India.},
  journal = {J Clin Diagn Res},
  year = {2014},
  volume = {8(5)},
  doi = {http://dx.doi.org/10.7860/JCDR/2014/7882.4380}
}
Akhtar J, Mallaredy V, Dandapat J, Maiti P, Sahoo SK, Singh S PEGylation of an osteoclast inhibitory peptide: suitable candidate for the treatment of osteoporosis. 2012 Int J Pharm.
Vol. 434(1-2), pp. 429-36 
article DOI  
Abstract: Osteoporosis is a condition of bone loss due to excessive osteoclastic activity. Several protein factors, such as receptor activator of nuclear factor kappa-B (RANK), receptor activator of nuclear factor kappa-B ligand (RANKL), osteoprotegerin (OPG), have been identified that are important in the pathogenesis of osteoporosis. RANKL binds to RANK and activates the NF-?B pathway by interaction of its cytoplasmic domain with an intracellular adapter protein, TNF receptor associated factors 6 (TRAF 6). This interaction can be inhibited by cell-permeable peptides that prevent RANK-TRAF 6 interaction. However, similar to the peptides/proteins used in clinical setting, the effective application of this TRAF 6 Inhibitory peptide as a therapeutic agent is marred by several limitations for instance short half-life, rapid renal clearance and immunogenicity. In the present study, we have developed PEGylated TRAF 6 Inhibitory peptide by conjugating TRAF 6 Inhibitory peptide to linear PEG backbone that exhibits longer bioavailability in plasma in the animal model. Besides, it has an enhanced uptake at its site of action, i.e., bone marrow.
BibTeX:
@article{AkhtarJ2012,
  author = {Akhtar J, Mallaredy V, Dandapat J, Maiti P, Sahoo SK, Singh S.},
  title = {PEGylation of an osteoclast inhibitory peptide: suitable candidate for the treatment of osteoporosis.},
  journal = {Int J Pharm.},
  year = {2012},
  volume = {434(1-2)},
  pages = {429-36},
  doi = {http://dx.doi.org/10.1016/j.ijpharm.2012.06.012}
}
Arora A, Srivastava D, Gupta H, Kumar V, Kotwal PP Sonographic diagnosis of subungual intraosseous epidermoid cyst 2013 J Clin Ultrasound
Vol. 41 Suppl 1, pp. 35-7 
article DOI  
Abstract: Intraosseous epidermoid cyst is an uncommon subungual mass. We report the sonographic findings in a case of intraosseous epidermoid cyst, which showed the characteristic whorled pattern of layers, previously described in other locations and unequivocally clinched the diagnosis in favor of this benign etiology and guided the management to phalangeal-sparing surgery
BibTeX:
@article{AroraA2013,
  author = {Arora A, Srivastava D, Gupta H, Kumar V, Kotwal PP},
  title = {Sonographic diagnosis of subungual intraosseous epidermoid cyst},
  journal = {J Clin Ultrasound},
  year = {2013},
  volume = {41 Suppl 1},
  pages = {35-7},
  doi = {http://dx.doi.org/10.1002/jcu.22058}
}
Arora K, Das RR, Arora A Teaching NeuroImages: fused brain: does face predict the brain? 2012 Neurology
Vol. 79(23) 
article DOI  
BibTeX:
@article{AroraK2012,
  author = {Arora K, Das RR, Arora A.},
  title = {Teaching NeuroImages: fused brain: does face predict the brain?},
  journal = {Neurology},
  year = {2012},
  volume = {79(23)},
  doi = {http://dx.doi.org/10.1212/WNL.0b013e3182768a0f}
}
Das B Gender differences in prevalence of musculoskeletal disorders among the rice farmers of West Bengal, India. 2013 Work  article  
Abstract: BACKGROUND:
Musculoskeletal disorder is one of the major health hazards among the rice farmers. Both men and women rice farmers have been shown to experience elevated risks of prevalence of work-relatedmusculoskeletal disorders (WMSD).
OBJECTIVE:
To estimate the different ergonomic risk factors associated with rice farming identify potential gender differences and the prevalence of musculoskeletal disorders (MSDs) among the rice farmers.
PARTICIPANTS:
Rice farmers - 110 men and 110 women were selected from the villages of West Bengal, India.
METHODS:
Modified Nordic Questionnaires were administered to assess the prevalence of MSDs. Detailed posture analysis was performed along with the administration of the Body-part Discomfort Scale. Objective measurements of physiological parameters and lung function values were also recorded.
RESULTS:
From this study it was revealed that the most subjects (99%) suffered discomfort at different parts of the body especially at low back (93.8%), shoulder (60.9%), hand (53.6%) and knee (80.9%) due to awkward posture (99%) and excessive repetitive task (95%) for a prolonged period of time. Both group of rice farmers suffered maximum discomfort feeling during digging (87.7%), sowing seeds (82.7%), harvesting (90.9%) and carrying crops (99%) activities. The farmers also suffered from severe physiological and thermal stress which hampered their other daily activities.
CONCLUSIONS:
The study conclude that women farmers felt significantly (p< 0.001) higher discomfort feeling than men rice farmers due to perform numerous household activities which further enhanced their discomfort feeling in their different body parts.
BibTeX:
@article{B2013,
  author = {Das B},
  title = {Gender differences in prevalence of musculoskeletal disorders among the rice farmers of West Bengal, India.},
  journal = {Work},
  year = {2013}
}
Bali N, Theivendran K, Prem H Computed tomography review of tarsal canal anatomy with reference to the fitting of sinus tarsi implants in the tarsal canal. 2013 J Foot Ankle Surg
Vol. 52(6), pp. 714-6 
article DOI  
Abstract: Sinus tarsi implants are used in the treatment of symptomatic hyperpronating flexible flatfeet in children. Although some implants are inserted only into the sinus tarsi, others occupy both the sinus tarsi and the tarsal canal. The stem that is anchored in the tarsal canal depends on interference fit for the initial resistance to slippage. The first part of this computed tomography anatomic study in children was aimed at finding and measuring the dimensions in the narrowest point in the canal that provided the interference fit. The second part of the study assessed the possibility of the implant being loaded with axial body weight in the tarsal canal. All foot computed tomography scans performed consecutively at Birmingham Children's Hospital from January 2008 to December 2011 were reviewed to assess the tarsal canal dimensions on the sagittal views. A total of 52 scans fulfilled the inclusion criteria. The average age was 12.7 years. The narrowest mean anteroposterior diameter of the canal was 7.3 ± 1.12 (range 5.2 to 10.0) mm. The narrowest mean superoinferior diameter was 9.2 ± 1.32 (range 6.3 to 12.7) mm. A total of 50 patients had the narrowest dimension in the anteroposterior plane. A positive linear correlation was found between the anteroposterior diameter and the superoinferior distance (r = 0.51, p < .01). We have concluded that the stem of an arthroereisis implant extending into the tarsal canal is unlikely to be constantly bearing body weight, because it obtains an interference grip in the anteroposterior direction in almost all patients and not in the superoinferior line of axial body weight.
BibTeX:
@article{BaliN2013,
  author = {Bali N, Theivendran K, Prem H.},
  title = {Computed tomography review of tarsal canal anatomy with reference to the fitting of sinus tarsi implants in the tarsal canal.},
  journal = {J Foot Ankle Surg},
  year = {2013},
  volume = {52(6)},
  pages = {714-6},
  doi = {http://dx.doi.org/10.1053/j.jfas.2013.07.008}
}
Bansal P, Kumar S, Mittal N, Kundu AK Collecting duct carcinoma: a rare renal tumor. 2012 Saudi J Kidney Dis Transpl.
Vol. 23(4), pp. 810-2 
article DOI  
Abstract: The most common primary malignant renal tumor is renal cell carcinoma (RCC), which accounts for 3% of all adult malignancies. Bellini duct carcinoma or collecting duct carcinoma is an unusual rare variant of RCC. This histologically distinct tumor is very rare, with less than 100 cases reported in the literature, and accounts for approximately 1% of all malignant renal epithelial tumors. We report two cases of collecting duct carcinoma and highlight the rarity of these tumors and their similarity to RCC.
BibTeX:
@article{BansalP2012,
  author = {Bansal P, Kumar S, Mittal N, Kundu AK.},
  title = {Collecting duct carcinoma: a rare renal tumor.},
  journal = {Saudi J Kidney Dis Transpl.},
  year = {2012},
  volume = {23(4)},
  pages = {810-2},
  doi = {http://dx.doi.org/10.4103/1319-2442.98166}
}
Bashir MS, Khade A, Borkar P, Saleem M, Lingaswamy V, Reddy D A comparative study between different pain rating scales in patients of osteoarthritis 2013 Indian J Physiol Pharmacol
Vol. 57(2), pp. 205-8 
article  
Abstract: Study was conducted to assess the sensitivity and simplicity of various pain rating scales in patients of osteoarthritis with chronic pain so that most appropriate scale can be identified. Scales included were Wong-Baker Faces Pain Rating Scale (WBS), Numerical Rating Scale (NRS), Faces Pain Scale- Revised (FPS-R), Visual Analogue Scale (VAS) and Verbal Rating Scale (VRS). Patients were asked to indicate their pain on these scales and comment about the simplicity of scales. Median mark for WBS, NRS, FPS-R, VAS and VRS was 10, 10, 10, 9.1 and 10 respectively. P value between WBS, NRS, FPS-R, VAS and VRS was insignificant. Most simple, easy to answer scale (83%) was WBS followed by FPS-R (17%). We conclude that all the scales are sensitive for assessment of the chronic osteoarthritis pain and are not different from each others. The most simple and preferred pain rating scale is WBS for the regional population.
BibTeX:
@article{BashirMS2013,
  author = {Bashir MS, Khade A, Borkar P, Saleem M, Lingaswamy V, Reddy D},
  title = {A comparative study between different pain rating scales in patients of osteoarthritis},
  journal = {Indian J Physiol Pharmacol},
  year = {2013},
  volume = {57(2)},
  pages = {205-8}
}
Bhavana SM, Nagalaxmi V, Maloth KN, Lakshmi CR, Deshpande PS Craniofacial fibrous dysplasia--a Morbid presentation. 2014 J Pak Med Assoc.
Vol. 64(3):, pp. 351-4 
article  
Abstract: Fibrous dysplasia is grouped under fibro-osseous lesions with developmental anomaly of bone forming mesenchyme that manifests as a defect in osteoblastic differentiation and maturation. This paper describes a case of 28 yrs old female who presented with swelling on right side of face, nostril and intraoral swelling on right half of hard palate since 1-year. The diagnosis was based on clinico-radiological and histopathological investigations. The appropriate management of patient included surgical modality along with placement of obturator to fill the defect. Follow up was done and till date there is no recurrence.
BibTeX:
@article{BhavanaSM2014,
  author = {Bhavana SM, Nagalaxmi V, Maloth KN, Lakshmi CR, Deshpande PS.},
  title = {Craniofacial fibrous dysplasia--a Morbid presentation.},
  journal = {J Pak Med Assoc.},
  year = {2014},
  volume = {64(3):},
  pages = {351-4}
}
Bihari V, Kesavachandran CN, Mathur N, Pangtey BS, Kamal R, Pathak MK, Srivastava AK Mathematically derived body volume and risk of musculoskeletal pain among housewives in North India. 2013 PLoS One.
Vol. 6;8(11) 
article DOI  
Abstract: BACKGROUND:
Global Burden of Disease Study 2010 demonstrates the impact of musculoskeletal diseasesas the second greatest cause of disability globally in all regions of the world. The study was conducted to determine the role of mathematically derived body volume (BV), body volume index (BVI), body mass index (BMI), body surface area (BSA) and body fat % (BF %) on musculoskeletal pain (MSP) among housewives in National Capital Region (NCR).
METHODS:
A cross sectional study was undertaken among 495 housewives from Gurgaon and New Okhla Industrial Development Area (NOIDA) in National Capital Region (NCR), New Delhi, India. The study includes questionnaire survey, clinical examination and body composition monitoring among housewives.
RESULTS:
A significantly higher BMI, BVI, BV and BSA were observed in subjects with MSP as compared to those who had no MSP. This was also true for subjects with pain in knee for BMI category for overweight. Subjects with pain in limbs had significantly high BMI and BVI as compared to subjects with no MSP. A significant positive correlation of age with BMI, BVI, BV and BSA was observed among subjects having no MSP denoting a direct relationship of age and these body factors.
CONCLUSIONS:
The prevalence of MSP among housewives is associated with increasing age, BMI and BVI. This can possibly be used for formulating a strategy for prevention of MSP.
BibTeX:
@article{BihariV2013,
  author = {Bihari V, Kesavachandran CN, Mathur N, Pangtey BS, Kamal R, Pathak MK, Srivastava AK.},
  title = {Mathematically derived body volume and risk of musculoskeletal pain among housewives in North India.},
  journal = {PLoS One.},
  year = {2013},
  volume = {6;8(11)},
  doi = {http://dx.doi.org/10.1371/journal.pone.0080133}
}
Chacko AG, Natarajan MS, Prabhu K1, Chacko G Schwannoma of supraorbital nerve presenting as a subfrontal tumor. 2014 Neurol India.
Vol. 62(1), pp. 96-8 
article DOI  
BibTeX:
@article{ChackoAG2014,
  author = {Chacko AG, Natarajan MS, Prabhu K1, Chacko G.},
  title = {Schwannoma of supraorbital nerve presenting as a subfrontal tumor.},
  journal = {Neurol India.},
  year = {2014},
  volume = {62(1)},
  pages = {96-8},
  doi = {http://dx.doi.org/10.4103/0028-3886.128353}
}
Chakrabarti S, Goswami BK, Paul PC, Sarkar S, Mondal S, Das S Clinicohaematological profile of aplastic anaemia in a rural medical college of Northern West Bengal. 2013 J Indian Med Assoc.
Vol. 111(10), pp. 670-3 
article  
Abstract: There is a scarcity of clinical data in the field of aplastic anaemia from rural India. Present study was conducted in North Bengal Medical College to find out the clinicohaematological profile and the possible aetiological factors in patients with aplastic anaemia. The study population (n = 83) included 21 children with male to female ratio 4.93:1. Weakness was present in all cases and pallor was present in 74.70% cases. Fever, bleeding episodes and localised infection were found in 55.42%, 48.19% and 27.71% cases respectively. There was no difference in clinical manifestations between children and adult except occurrence of fever (p = 0.0365). We identified possible aetiological factors in 32.53% cases as relevant drug intake in 10.84%, exposure to chemicals in 13.25% and hepatitis in 8.43% cases. We found low mean haemoglobin (3.81 +/- 1.71 g/dl), leucocyte and platelet (3.05 +/- 1.3 and 37.30 +/- 35 x 10(3)/cmm), neutrophil (30.28 +/- 21.76%) and high lymphocyte (67.27 +/- 22.50%) in peripheral blood. At the time of presentation, aplastic anaemia was moderate in 59.04% cases, severe in 48.19% cases and mild in 4.82% cases. We estimated the prevalence of aplastic anaemia in 4 districts of West Bengal including tea garden areas was 2.98/million populations per year. It was concluded that aplastic anaemia is a major non-malignant haematological disease in this part of India, and an increasing use of chemicals in agricultural and tea garden areas might be the responsible factor. Larger population based study is suggested.
BibTeX:
@article{ChakrabartiS2013,
  author = {Chakrabarti S, Goswami BK, Paul PC, Sarkar S, Mondal S, Das S.},
  title = {Clinicohaematological profile of aplastic anaemia in a rural medical college of Northern West Bengal.},
  journal = {J Indian Med Assoc.},
  year = {2013},
  volume = {111(10)},
  pages = {670-3}
}
Chakravarthy VK, Chandra DN, Venkataratnam G Glandular odontogenic cyst: a case report. 2013 J Indian Med Assoc.
Vol. 111(6), pp. 408-9 
article  
Abstract: A case of glandular odontogenic cyst was diagnosed in a 33-year-old man. The cyst was located in the angle of the mandible, underneath the left molars. This case has been presented for its rarity of location in posterior mandible and presentation as intra-oral papillary growth
BibTeX:
@article{ChakravarthyVK2013,
  author = {Chakravarthy VK, Chandra DN, Venkataratnam G},
  title = {Glandular odontogenic cyst: a case report.},
  journal = {J Indian Med Assoc.},
  year = {2013},
  volume = {111(6)},
  pages = {408-9}
}
Chandra RV, Anumala N, Vikrant V An asymptomatic orthodontic bracket in the mandibular alveolar bone region. 2013 BMJ Case Rep.
Vol. 27 
article DOI  
BibTeX:
@article{ChandraRV2013,
  author = {Chandra RV, Anumala N, Vikrant V},
  title = {An asymptomatic orthodontic bracket in the mandibular alveolar bone region.},
  journal = {BMJ Case Rep.},
  year = {2013},
  volume = {27},
  doi = {http://dx.doi.org/10.1136/bcr-2013-009866}
}
Chandra SP, Singh A, Goyal N, Laythalling RK, Singh M, Kale SS, Sharma MS, Suri A, Singh P, Garg A, Sarkar C,Tripathi M, Sharma BS, Mahapatra AK Analysis of changing paradigms of management in 179 patients with spinal tuberculosis over a 12-year period and proposal of a new management algorithm. 2013 World Neurosurg.
Vol. 80(1-2), pp. 190-203 
article DOI  
Abstract: OBJECTIVE:
To describe management and outcome in a large cohort of patients with spinal tuberculosis (TB).
METHODS:
Of 212 patients with spinal TB treated between January 1999 and June 2011, 179 patients were included in the study (?6 months follow-up; mean age, 34.8 years; age range, 10-75 years). The cohort was divided into two groups (n = 89 and n = 90); group I was treated from 1999-2003, and group II was treated from 2004-2011.
RESULTS:
The study cohort comprised 93 male patients. Mean age was 34.8 years ± 7.2 (range, 10-75 years). Mean duration of symptoms was 2.4 months. Sensorimotor deficits were present in 167 patients (93.5%; 74 patients were paraplegic), pain was present in 156 patients (87%), bladder involvement was present in 127 patients (71.7%), and extraspinal TB was present in 36 patients (22.3%). Of patients, 92% were receiving prior chemotherapy; one fifth of these patients were on second-line chemotherapy. Thoracic spine involvement was most common (n = 86; 57%), followed by cervical spine (n = 50; 29%), craniovertebral junction (n = 22; 15%), and lumbosacral spine (n = 20; 10.5%). Surgery was performed in 146 patients (68% instrumented fusions and 16% circumferential fusions). Mean follow-up was 20.2 months (range, 6-60 months). Sensorimotor deficits improved in 89% of patients, pain improved in 71%, bladder symptoms improved in 88%, and paraplegia improved in 77%. Patients in group II had a higher incidence of cord compression (P < 0.01), severe vertebral body collapse (P < 0.001), and paraplegia (P < 0.001). Group II patients underwent more instrumented surgeries (P < 0.01), especially circumferential fusions (P < 0.001). The improvement in paraplegia was better after 2004 (group II). Bladder symptoms correlated with the timing of surgery (P < 0.1).
CONCLUSIONS:
Medical treatment of spinal TB is the mainstay; however, radical, instrumented surgeries should be offered when indicated. The presence of paraplegia should not preclude surgery. A practical management paradigm is also suggested.
BibTeX:
@article{ChandraSP2013,
  author = {Chandra SP, Singh A, Goyal N, Laythalling RK, Singh M, Kale SS, Sharma MS, Suri A, Singh P, Garg A, Sarkar C,Tripathi M, Sharma BS, Mahapatra AK.},
  title = {Analysis of changing paradigms of management in 179 patients with spinal tuberculosis over a 12-year period and proposal of a new management algorithm.},
  journal = {World Neurosurg.},
  year = {2013},
  volume = {80(1-2)},
  pages = {190-203},
  doi = {http://dx.doi.org/10.1016/j.wneu.2012.12.019}
}
Chhabra P, Gupta N, Kaushik A Compartment syndrome as a spectrum of purple glove syndrome following intravenous phenytoin administration in a young male: a case report and review of literature 2013 Neurol India
Vol. 61(4), pp. 419-20 
article DOI  
Abstract: Compartment syndrome is a rare complication of spectrum of purple glove syndrome, seen as a side effect of intravenous phenytoin. This involves rapid discolouration of the involved limb along with edema and sometimes blistering of the skin also. Treatment is usually conservative and rarely requires surgery. We present a case of compartment syndrome following intravenous phenytoin administration and review of literature related to the case.
BibTeX:
@article{ChhabraP2013,
  author = {Chhabra P, Gupta N, Kaushik A.},
  title = {Compartment syndrome as a spectrum of purple glove syndrome following intravenous phenytoin administration in a young male: a case report and review of literature},
  journal = {Neurol India},
  year = {2013},
  volume = {61(4)},
  pages = {419-20},
  doi = {http://dx.doi.org/10.4103/0028-3886.117611}
}
Desai M, Talwar S, Kothari SS, Jagia P, Airan B Inferior vena cava to left atrium shunt presenting with polycythemia and stroke three decades following closure of atrial septal defect. 2013 Congenit Heart Dis.
Vol. 8(4), pp. 102-5 
article DOI  
Abstract: We report an adult patient presenting with polycythemia and stroke, three decades following surgical closure of an atrial septal defect. The avoidance, diagnosis, and management of this complication are discussed.
BibTeX:
@article{DesaiM2013,
  author = {Desai M, Talwar S, Kothari SS, Jagia P, Airan B.},
  title = {Inferior vena cava to left atrium shunt presenting with polycythemia and stroke three decades following closure of atrial septal defect.},
  journal = {Congenit Heart Dis.},
  year = {2013},
  volume = {8(4)},
  pages = {102-5},
  doi = {http://dx.doi.org/10.1111/j.1747-0803.2012.00685.x}
}
Bhatt DL Ask the doctor. I was having occasional chest pains, and my primary care physician recommended a stress test. Because I have bad knees, the cardiologist had me take a stress test using a medication instead of doing exercise. Fortunately, the results were normal. But it made me wonder: is one type better than the other? 2014 Harv Heart Lett.
Vol. 24(7), pp. 2 
article  
BibTeX:
@article{DL.2014,
  author = {Bhatt DL.},
  title = {Ask the doctor. I was having occasional chest pains, and my primary care physician recommended a stress test. Because I have bad knees, the cardiologist had me take a stress test using a medication instead of doing exercise. Fortunately, the results were normal. But it made me wonder: is one type better than the other?},
  journal = {Harv Heart Lett.},
  year = {2014},
  volume = {24(7)},
  pages = {2}
}
Paramdeep G Efficacy and tolerability of ginger (Zingiber officinale) in patients of osteoarthritis of knee. 2013 Indian J Physiol Pharmacol.
Vol. 57(2):, pp. 177-83. 
article  
Abstract: Osteoarthritis (OA) is a chronic degenerative disorder of synovial joints and a common cause of locomotor disability. NSAIDs are routinely used for symptomatic treatment and are associated with side effects which have led to the increased interest towards alternative treatment options. This study was conducted to evaluate the safety and efficacy of ginger in management of OA. Sixty patients of OA of knee were enrolled in randomized open label study and divided into three groups of 20 each. Group I received tab. Diclofenac 50 mg and cap. placebo, group II received cap. ginger 750 mg and cap. placebo and group III received cap. ginger 750 mg and tab. diclofenac 50 mg. The assessment of efficacy was done at every 2 weeks till 12 weeks, by using Western Ontario and McMaster Universities osteoarthritis (WOMAC) index, Visual Analogue Scale (VAS) and the safety assessment was done by noting adverse events during the study. The analysis of WOMAC score and VAS score in all the three groups showed statistically significant improvement with time in all groups. On comparison among three groups, group III patients who received both ginger and diclofenac showed numerically superior improvement than the individual treatments. There was no statistically significant difference among three groups in case of adverse events. Ginger powder has add-on effect on reducing the symptoms of OA of knee with acceptable safety profile.
BibTeX:
@article{G.2013,
  author = {Paramdeep G.},
  title = {Efficacy and tolerability of ginger (Zingiber officinale) in patients of osteoarthritis of knee.},
  journal = {Indian J Physiol Pharmacol.},
  year = {2013},
  volume = {57(2):},
  pages = {177-83.}
}
Gandhi A, Yadav P, Gandhi T Endodontic-periodontal management of a maxillary lateral incisor with an associated radicular lingual groove and severe periapical osseous destruction--a case report. 2012 J Ir Dent Assoc.
Vol. 58(2), pp. 95-100. 
article  
Abstract: Radicular lingual grooves are morphological defects, which are found most frequently in maxillary anterior teeth and are a predisposing factor for periodontal disease. They are easily overlooked as aetiologic factors, as these grooves are covered by periodontal tissues. This case report presents a successful management of a case of a maxillary lateral incisor with an associated radicular lingual groove and severe periapical osseous destruction in a 30-year-old female patient. A combination of endodontic treatment, radiculoplasty to eliminate the radicular lingual groove, and periapical surgery to eliminate the periapical osseous defect was used. At two-year follow-up, the patient was comfortable and complete resolution of the periapical pathology was evident.
BibTeX:
@article{GandhiA2012,
  author = {Gandhi A, Yadav P, Gandhi T.},
  title = {Endodontic-periodontal management of a maxillary lateral incisor with an associated radicular lingual groove and severe periapical osseous destruction--a case report.},
  journal = {J Ir Dent Assoc.},
  year = {2012},
  volume = {58(2)},
  pages = {95-100.}
}
Garg A, Utreja AK, Singh SP, Rattan V, Jena AK Midsymphyseal distraction osteogenesis with lingual tooth-supported distractor: a case report. 2014 J Calif Dent Assoc
Vol. 42(3), pp. 179-86 
article  
Abstract: This report presents the treatment of a patient with severe mandibular anterior crowding caused by anterior transverse deficiency of the mandible. The treatment plan called for midsymphyseal distraction osteogenesis. A tooth-supported distractor placed on the lingual aspect of the mandible was used for mandibular widening.
BibTeX:
@article{GargA2014,
  author = {Garg A, Utreja AK, Singh SP, Rattan V, Jena AK.},
  title = {Midsymphyseal distraction osteogenesis with lingual tooth-supported distractor: a case report.},
  journal = {J Calif Dent Assoc},
  year = {2014},
  volume = {42(3)},
  pages = {179-86}
}
Ghosh S, Chakrabarti S, Chakraborty J, Das S Retroperitoneal mass: a diagnostic challenge 2013 J Nepal Health Res Counc.
Vol. 11(24), pp. 215-7 
article  
Abstract: We report a case of retroperitoneal mass involving lumbar spine (L2 region) of eight months duration in a male aged 26 years. X ray of the lumbar spine was suggestive of tuberculosis. However, as there was no response to specific therapy, a CT scan was performed which was indicative of a soft tissue sarcoma. Subsequent biopsy of the tumor showed it to be a giant cell tumor of bone (GCT). The tumor was inoperable and the patient is presently undergoing radiotherapy. Giant cell tumors only rarely arise in the axial skeleton. GCT of the spine is uncommon, accounting for 1.3-6.5% of all cases in various series. The case is being presented because of its rarity, diagnostic dilemma encountered and to emphasize the role of surgical biopsy.
BibTeX:
@article{GhoshS2013,
  author = {Ghosh S, Chakrabarti S, Chakraborty J, Das S},
  title = {Retroperitoneal mass: a diagnostic challenge},
  journal = {J Nepal Health Res Counc.},
  year = {2013},
  volume = {11(24)},
  pages = {215-7}
}
Goswami RP, Pal D, Das S, Ray Y, Rahman M Multiple intramuscular and hepatic echinococcosis. 2013 J Assoc Physicians India.
Vol. 61(12):, pp. 907-8. 
article  
BibTeX:
@article{GoswamiRP2013,
  author = {Goswami RP, Pal D, Das S, Ray Y, Rahman M.},
  title = {Multiple intramuscular and hepatic echinococcosis.},
  journal = {J Assoc Physicians India.},
  year = {2013},
  volume = {61(12):},
  pages = {907-8.}
}
Gowda N, Kumar MJ, Kumar AK Black hip: a rare case treated by total hip replacement. 2013 Ann Saudi Med.
Vol. 33(4), pp. 368-71 
article DOI  
Abstract: BACKGROUND AND OBJECTIVE:
Ochronic arthropathy of hip (Black Hip) is a rare clinical manifestation of congenital disorder of amino acid metabolism characterized by a classic triad: (1) degenerative arthritis, (2) ochronotic pigmentation, and (3) urine that turns black on long standing or alkalinization. We report a case of ochronic arthropathy of the left hip joint that was successfully treated by total hip arthroplasty.
DESIGN AND SETTINGS:
This is a case study conducted at PES Medical College, Andhra Pradesh, India.
PATIENTS AND METHODS:
A 60-year-old female patient came with a history of progressive pain in her left hip joint for the last 8 months. She was diagnosed to be suffering from ochronic arthritis of left hip.
RESULTS:
After tissue confirmation she was operated with total hip replacement. At the end of 2 years, the patient was symptom free without any implant loosening.
CONCLUSION:
Ochronotic arthropathy is a rare metabolic disorder that can be underdiagnosed many a times. Early management is only symptomatic, and advanced cases need surgical intervention. Vitamin preparations are given because of the influence of vitamin C on tyrosine and phenylalanine metabolism. In the cases of severe degenerative arthritis of hip, total hip replacement may be considered as a surgical option.
BibTeX:
@article{GowdaN2013,
  author = {Gowda N, Kumar MJ, Kumar AK.},
  title = {Black hip: a rare case treated by total hip replacement.},
  journal = {Ann Saudi Med.},
  year = {2013},
  volume = {33(4)},
  pages = {368-71},
  doi = {http://dx.doi.org/10.5144/0256-4947.2013.368}
}
Gupta V, Sandeep HS, Rai A, Shukla J Functional and radiological assessment of arthropathy in Indian children with haemophilia. 2013 Haemophilia
Vol. 19(6), pp. 373-5 
article DOI  
BibTeX:
@article{GuptaV2013,
  author = {Gupta V, Sandeep HS, Rai A, Shukla J},
  title = {Functional and radiological assessment of arthropathy in Indian children with haemophilia.},
  journal = {Haemophilia},
  year = {2013},
  volume = {19(6)},
  pages = {373-5},
  doi = {http://dx.doi.org/10.1111/hae.12215}
}
Shah H Perthes disease: evaluation and management. 2014 Orthop Clin North Am
Vol. 45(1), pp. 87-97 
article DOI  
Abstract: Perthes disease refers to self-limiting idiopathic avascular necrosis of capital femoral epiphysis in a child. There is no consensus for the optimum treatment of Perthes disease even 100 years after the first description. The prime aim of the treatment is to maintain the sphericity of the femoral head and the congruency of the femur-acetabulum relationship to prevent secondary degenerative arthritis. Early diagnosis and management can help the collapse of femoral head, progressive femoral head deformity, and impingement.
BibTeX:
@article{H.2014,
  author = {Shah H.},
  title = {Perthes disease: evaluation and management.},
  journal = {Orthop Clin North Am},
  year = {2014},
  volume = {45(1)},
  pages = {87-97},
  doi = {http://dx.doi.org/10.1016/j.ocl.2013.08.005}
}
Iyer SS, Haribabu PK Minimizing alveolar bone loss during and after extractions (Part I)--review of techniques: atraumatic extraction, root retention. 2013 Alpha Omegan.
Vol. 106(3-4):, pp. 67-72. 
article  
BibTeX:
@article{IyerSS2013,
  author = {Iyer SS, Haribabu PK},
  title = {Minimizing alveolar bone loss during and after extractions (Part I)--review of techniques: atraumatic extraction, root retention.},
  journal = {Alpha Omegan.},
  year = {2013},
  volume = {106(3-4):},
  pages = {67-72.}
}
Singh JA Folic acid supplementation for rheumatoid arthritis patients on methotrexate: the good gets better. 2013 Cochrane Database Syst Rev
Vol. 22;7 
article DOI  
BibTeX:
@article{JA.2013,
  author = {Singh JA.},
  title = {Folic acid supplementation for rheumatoid arthritis patients on methotrexate: the good gets better.},
  journal = {Cochrane Database Syst Rev},
  year = {2013},
  volume = {22;7},
  doi = {http://dx.doi.org/10.1002/14651858}
}
Jaiswal A, Vijay V, Kori P, Shukla R Aneurysmal bone cyst of thoracic spine: case report and brief review of literature. 2013 BMJ Case Rep.
Vol. 27 
article DOI  
Abstract: A 16-year-old girl was admitted with insidious onset, gradually progressive spastic sensori-motor paraparesis, with a sensory level at D10 dermatome without bowel or bladder involvement for the last 2 months following trivial trauma on the lower back. MRI of the spine showed a low-to-intermediate signal intensity, heterogeneous mass with multiple fluid levels. A diagnosis of aneurysmal bone cyst was made. A D8-D9 laminectomy with near total excision of mass was performed. Histopathology of the mass showed cyst cavity filled with haemorrhage surrounded by bony trabeculae confirming the diagnosis. Following excision the patient had excellent recovery. We report this case owing to its rarity and to emphasise the importance of surgery if there is cord compression.
BibTeX:
@article{JaiswalA2013,
  author = {Jaiswal A, Vijay V, Kori P, Shukla R.},
  title = {Aneurysmal bone cyst of thoracic spine: case report and brief review of literature.},
  journal = {BMJ Case Rep.},
  year = {2013},
  volume = {27},
  doi = {http://dx.doi.org/10.1136/bcr-2013-009265}
}
Jayaprakash B, Prajeesh B, Nair DS Gorham's disease. 2013 J Assoc Physicians India.
Vol. 61(12), pp. 941-3. 
article  
Abstract: Gorham's disease is a rare disorder characterised by proliferation of vascular channels that result in destruction and resorption of osseous matrix. A case of Gorham's disease presenting as chylothorax and osteolysis of ribs is presented.
BibTeX:
@article{JayaprakashB2013,
  author = {Jayaprakash B, Prajeesh B, Nair DS.},
  title = {Gorham's disease.},
  journal = {J Assoc Physicians India.},
  year = {2013},
  volume = {61(12)},
  pages = {941-3.}
}
Jiji G, Thippeswami SH, Abhilasha S Myoepithelial carcinoma ex pleomorphic adenoma: a rare intraosseous entity. 2012 Oral Surg Oral Med Oral Pathol Oral Radiol.
Vol. 114(1), pp. 4 
article DOI  
BibTeX:
@article{JijiG2012,
  author = {Jiji G, Thippeswami SH, Abhilasha S},
  title = {Myoepithelial carcinoma ex pleomorphic adenoma: a rare intraosseous entity.},
  journal = {Oral Surg Oral Med Oral Pathol Oral Radiol.},
  year = {2012},
  volume = {114(1)},
  pages = {4},
  doi = {http://dx.doi.org/10.1016/j.oooo.2011.10.046}
}
Joshi R, Kapdi M Pseudohypoparathyroidism type 1b with hypothyroidism. 2012 Indian Pediatr.
Vol. 49(8), pp. 667-8 
article  
Abstract: Pseudohypoparathyroidism due to deficient end organ response to parathyroid hormone (PTH) is characterized by hypocalcemia, hyperphosphatemia and increased serum PTH. We report a case of an 8-year-old girl with pseudohypoparathyroidism without features of Albright's hereditary osteodystrophy. The case is of interest as the child on serial follow-up over a period of 2 years developed hypothyroidism. This is a rare feature seen in pseudohypoparathyroidism type1b
BibTeX:
@article{JoshiR2012,
  author = {Joshi R, Kapdi M.},
  title = {Pseudohypoparathyroidism type 1b with hypothyroidism.},
  journal = {Indian Pediatr.},
  year = {2012},
  volume = {49(8)},
  pages = {667-8}
}
Kannan MA, Sundaram C, Uppin M, Mridula R, Jabeen SA, Borgohain R, Murthy JM Incidence of malignancies in biopsy-proven inflammatory myopathy: comment and erratum. Author reply. 2013 Neurol India.
Vol. 61(3), pp. 340 
article  
BibTeX:
@article{KannanMA2013,
  author = {Kannan MA, Sundaram C, Uppin M, Mridula R, Jabeen SA, Borgohain R, Murthy JM},
  title = {Incidence of malignancies in biopsy-proven inflammatory myopathy: comment and erratum. Author reply.},
  journal = {Neurol India.},
  year = {2013},
  volume = {61(3)},
  pages = {340}
}
Kapoor PG, Chabbra R Neuroblastoma presenting as raccoon eyes 2014 J Pediatr.
Vol. 164(6):, pp. 1495. 
article DOI  
BibTeX:
@article{KapoorPG2014,
  author = {Kapoor PG, Chabbra R.},
  title = {Neuroblastoma presenting as raccoon eyes},
  journal = {J Pediatr.},
  year = {2014},
  volume = {164(6):},
  pages = {1495.},
  doi = {http://dx.doi.org/10.1016/j.jpeds.2014.02.001}
}
Kendre B, Deopujari C, Karmarkar V, Ratha V A rare case of carcinoma rectum metastasing to clivus. 2014 Neurol India
Vol. 62(1), pp. 85-6 
article DOI  
BibTeX:
@article{KendreB2014,
  author = {Kendre B, Deopujari C, Karmarkar V, Ratha V},
  title = {A rare case of carcinoma rectum metastasing to clivus.},
  journal = {Neurol India},
  year = {2014},
  volume = {62(1)},
  pages = {85-6},
  doi = {http://dx.doi.org/10.4103/0028-3886.128343}
}
Khajuria DK, Razdan R, Mahapatra DR, Bhat MR Osteoprotective effect of propranolol in ovariectomized rats: a comparison with zoledronic acid and alfacalcidol. 2013 J Orthop Sci.
Vol. 18(5), pp. 832-42 
article DOI  
Abstract: BACKGROUND:
Currently ?-adrenergic receptor blockers are considered to be potential drugs under investigation for preventive or therapeutic effect in osteoporosis. However, there is no published data showing the comparative study of ?-blockers with well accepted agents for the treatment of osteoporosis. To address this question, we compared the effects of propranolol with well accepted treatments like zoledronic acid and alfacalcidol in an animal model of postmenopausal osteoporosis.
METHODS:
Five days after ovariectomy, 36 ovariectomized (OVX) rats were divided into 6 equal groups, randomized to treatments zoledronic acid (100 ?g/kg, intravenous single dose); alfacalcidol (0.5 ?g/kg, oral gauge daily); propranolol (0.1 mg/kg, subcutaneously 5 days per week) for 12 weeks. Untreated OVX and sham OVX were used as controls. At the end of treatment serum calcium and alkaline phosphatase were assayed. Femurs were removed and tested for bone density, bone porosity, bone mechanical properties and trabecular micro-architecture.
RESULTS:
Propranolol showed a significant decrease in alkaline phosphatase levels and bone porosity in comparison to OVX control. Moreover, propranolol significantly improved bone density, bone mechanical properties and inhibited the deterioration of trabecular microarchitecture when compared with OVX control. The osteoprotective effect of propranolol was comparable with zoledronic acid and alfacalcidol.
CONCLUSIONS:
Based on this comparative study, the results strongly suggest that propranolol can be a candidate therapeutic drug for the management of postmenopausal osteoporosis.
BibTeX:
@article{KhajuriaDK2013,
  author = {Khajuria DK, Razdan R, Mahapatra DR, Bhat MR.},
  title = {Osteoprotective effect of propranolol in ovariectomized rats: a comparison with zoledronic acid and alfacalcidol.},
  journal = {J Orthop Sci.},
  year = {2013},
  volume = {18(5)},
  pages = {832-42},
  doi = {http://dx.doi.org/10.1007/s00776-013-0433-y}
}
Kumar M, Chawla R, Haloi P, Singh M The use of caffeine for the treatment of apnea of prematurity and bradycardia in a holoprosencephalic child with cleft lip and palate. 2013 J Clin Anesth.
Vol. 25(8), pp. 678-9 
article DOI  
BibTeX:
@article{KumarM2013,
  author = {Kumar M, Chawla R, Haloi P, Singh M.},
  title = {The use of caffeine for the treatment of apnea of prematurity and bradycardia in a holoprosencephalic child with cleft lip and palate.},
  journal = {J Clin Anesth.},
  year = {2013},
  volume = {25(8)},
  pages = {678-9},
  doi = {http://dx.doi.org/10.1016/j.jclinane.2013.07.007}
}
Kumar MN, Gopalakrishna C Modified Ponseti method of management of neonatal club feet. 2012 Acta Orthop Belg.
Vol. 78(2), pp. 210-5. 
article  
Abstract: The aim of this study was to assess the outcome of a new protocol for the management of neonatal clubfeet that can be considered as a modification of the Ponseti method. The modifications consisted of performing the tenotomy of the Achilles tendon prior to the application of the first cast and using only one cast for a period of 3 weeks following tenotomy. We applied the modified method in 50 children (82 club feet) and assessed the degree of deformity using the Pirani and the Dimeglio scoring systems. The minimum follow-up period was 28 months (range: 24-32). The intermediate range follow-up results of this study showed that the modified Ponseti method was associated with a good outcome in 85% of cases of neonatal club feet with a Pirani score of 5 or less and a Dimeglio score of 15 or less. Persistently high Pirani or Dimeglio scores immediately after tenotomy and poor compliance with splintage were predictors of failure of the modified technique.
BibTeX:
@article{KumarMN2012,
  author = {Kumar MN, Gopalakrishna C.},
  title = {Modified Ponseti method of management of neonatal club feet.},
  journal = {Acta Orthop Belg.},
  year = {2012},
  volume = {78(2)},
  pages = {210-5.}
}
Kumar S, Pile K, Danda D Juvenile dermatomyositis management: moving but in need of a push. 2013 Int J Rheum Dis.
Vol. 16(5):, pp. 497-8 
article DOI  
BibTeX:
@article{KumarS2013,
  author = {Kumar S, Pile K, Danda D},
  title = {Juvenile dermatomyositis management: moving but in need of a push.},
  journal = {Int J Rheum Dis.},
  year = {2013},
  volume = {16(5):},
  pages = {497-8},
  doi = {http://dx.doi.org/10.1111/1756-185X.12216}
}
Kumar S, Valiathan A, Jayaswal P, Sivakumar A Class II treatment of an adolescent patient with a history of acute lymphocytic leukemia. 2011 J Clin Orthod.
Vol. 45(12), pp. 661-5 
article  
BibTeX:
@article{KumarS2011,
  author = {Kumar S, Valiathan A, Jayaswal P, Sivakumar A},
  title = {Class II treatment of an adolescent patient with a history of acute lymphocytic leukemia.},
  journal = {J Clin Orthod.},
  year = {2011},
  volume = {45(12)},
  pages = {661-5}
}
Kumar V, Kalra S, Mutreja D, Arya A Rickets associated with ichthyosis. 2012 Paediatr Int Child Health.
Vol. 32(2):, pp. 119-20 
article DOI  
Abstract: Nutritional rickets in disorders of keratinisation is very rare. A 12-year-old girl with autosomal dominant ichthyosis vulgaris is reported who presented with tetany and a waddling gait. She had the classic clinical, biochemical and radiological features of rickets. She was treated with vitamin D and calcium supplements together with keratolytic and emollient agents, which was followed by biochemical and clinical remission. This appears to be the first report of rickets associated with autosomal dominant ichthyosis vulgaris.
BibTeX:
@article{KumarV2012,
  author = {Kumar V, Kalra S, Mutreja D, Arya A},
  title = {Rickets associated with ichthyosis.},
  journal = {Paediatr Int Child Health.},
  year = {2012},
  volume = {32(2):},
  pages = {119-20},
  doi = {http://dx.doi.org/10.1179/2046905511Y.0000000013}
}
Kundu ZS, Gupta V, Gogna P, Sangwan SS Partial-limb salvage after persistent infection in the distal femoral prosthesis: straight-plasty--a novel technique 2014 J Coll Physicians Surg Pak.
Vol. 24(3), pp. 213-5 
article DOI  
Abstract: A 35 years old female had giant cell tumour (GCT) of the distal femur for which wide resection and distal femoral endoprosthetic replacement was performed. Massive infection of prosthesis required removal and replacement of the prosthesis with nail antibiotic cement spacer, which also proved to be futile. Ultimately the whole of the infected thigh had to be excised. The limb could be preserved partially using straight-plasty instead of amputation. Patient is well rehabilitated and doing well at a follow-up of 3 years.
BibTeX:
@article{KunduZS2014,
  author = {Kundu ZS, Gupta V, Gogna P, Sangwan SS.},
  title = {Partial-limb salvage after persistent infection in the distal femoral prosthesis: straight-plasty--a novel technique},
  journal = {J Coll Physicians Surg Pak.},
  year = {2014},
  volume = {24(3)},
  pages = {213-5},
  doi = {http://dx.doi.org/03.2014/JCPSP.213215.}
}
Manchanda AS, Narang RS Calcifying odontogenic cyst: dilemma in classification. 2014 N Y State Dent J
Vol. 80(3):, pp. 27-9 
article  
Abstract: •Calcifying odontogenic cyst (COC) shows extreme diversity in its clinical and histopathological features, as well as in its biological behavior. Because of this diversity, there has been confusion and disagreement on the terminology and classification of this lesion. Attempts to classify COC can be divided into two concepts: monistic and dualistic. We present a case of COC with coexisting histopathologic features of a cyst and a neoplasm, thus posing a dilemma in the terminology used to categorize and classify it.
BibTeX:
@article{ManchandaAS2014,
  author = {Manchanda AS, Narang RS.},
  title = {Calcifying odontogenic cyst: dilemma in classification.},
  journal = {N Y State Dent J},
  year = {2014},
  volume = {80(3):},
  pages = {27-9}
}
Mathew AJ, Rahim A, Bina T, Paul BJ, Chopra A A call to integrate musculoskeletal disorders into the national programme for non-communicable diseases (NCD). 2012 Indian J Med Res.
Vol. 136(3), pp. 499-501 
article  
BibTeX:
@article{MathewAJ2012,
  author = {Mathew AJ, Rahim A, Bina T, Paul BJ, Chopra A.},
  title = {A call to integrate musculoskeletal disorders into the national programme for non-communicable diseases (NCD).},
  journal = {Indian J Med Res.},
  year = {2012},
  volume = {136(3)},
  pages = {499-501}
}
Mohanan S, Chandrashekar L, Semple RK, Thappa DM, Parameswaran N, Negi VS, Ramassamy S Rabson-Mendenhall syndrome with recurrent cerebral infarcts caused by a novel INSR mutation. 2013 Int J Dermatol
Vol. 52(2), pp. 182-5 
article DOI  
Abstract: Rabson-Mendenhall syndrome (RMS) is an autosomal recessive disorder characterized by extreme insulin resistance and certain characteristic phenotypic features. The primary defect lies in the insulin receptor and involves biallelic mutations that lead to a loss of function through various postulated defects. We present a 9-year-old female patient with RMS complicated by multiple cerebral infarcts, in whom genetic analysis revealed a novel insulin receptor mutation.
BibTeX:
@article{MohananS2013,
  author = {Mohanan S, Chandrashekar L, Semple RK, Thappa DM, Parameswaran N, Negi VS, Ramassamy S.},
  title = {Rabson-Mendenhall syndrome with recurrent cerebral infarcts caused by a novel INSR mutation.},
  journal = {Int J Dermatol},
  year = {2013},
  volume = {52(2)},
  pages = {182-5},
  doi = {http://dx.doi.org/10.1111/j.1365-4632.2012.05665.x}
}
Mohanty CB, Rao KV, Sampath S Pediatric cervical intraosseous schwannoma. 2012 Pediatr Neurosurg.
Vol. 48(6), pp. 364-70 
article DOI  
Abstract: Intraosseous schwannoma of the spine is an extremely rare tumor, with only 18 cases reported so far in the literature. We describe the 1st case of intraosseous schwannoma in the pediatric age group, which was treated successfully, and we review the pertinent literature.
BibTeX:
@article{MohantyCB2012,
  author = {Mohanty CB, Rao KV, Sampath S.},
  title = {Pediatric cervical intraosseous schwannoma.},
  journal = {Pediatr Neurosurg.},
  year = {2012},
  volume = {48(6)},
  pages = {364-70},
  doi = {http://dx.doi.org/10.1159/000351734}
}
Mohindra S, Savardekar A, Tripathi M, Rane S En plaque foramen magnum meningiomas: rare presentations. 2012 Br J Neurosurg
Vol. 26(6), pp. 899-901 
article DOI  
Abstract: Only 1.8-3.2% of all meningiomas are located at foramen magnum (FM). As these tumours are indolent, there occurs a long interval between onset of symptoms and diagnosis. This diagnostic delay may get accentuated, if unusual clinical features or radiological features are seen. The authors present two cases of FM meningiomas, with rare radiological features, one with intense bony hyperostosis and another with circumferentially, constricting en-plaque meningioma.
BibTeX:
@article{MohindraS2012,
  author = {Mohindra S, Savardekar A, Tripathi M, Rane S.},
  title = {En plaque foramen magnum meningiomas: rare presentations.},
  journal = {Br J Neurosurg},
  year = {2012},
  volume = {26(6)},
  pages = {899-901},
  doi = {http://dx.doi.org/10.3109/02688697.2012.685781}
}
Mukherjee SK, Panthagani A, Ramroop N, Al-Dujaily S Pulmonary embolus as a first presentation of occult metastatic prostate cancer. 2012 BMJ Case Rep
Vol. 7 
article DOI  
Abstract: A 65-year-old gentleman with a previous history of pulmonary embolus presented with a subacute onset of shortness of breath, haemoptysis and chest pain associated with a swollen left leg. Ultrasound Doppler scanning of the leg revealed no deep-vein thrombosis. Thereafter, a CT scan of the pulmonary vasculature revealed a large right-sided pulmonary embolus. CT scanning of the abdomen and pelvis was performed to look for evidence of an intra-abdominal source of thrombus and revealed evidence of a moderate sized pelvic mass causing obstructive uropathy. Urological review of the patient revealed a hard prostate and raised prostate specific antigen, consistent with a diagnosis of primary prostatic carcinoma, which after investigation with a radioisotope bone scan was found to have metastasised to the bony pelvis
BibTeX:
@article{MukherjeeSK2012,
  author = {Mukherjee SK, Panthagani A, Ramroop N, Al-Dujaily S.},
  title = {Pulmonary embolus as a first presentation of occult metastatic prostate cancer.},
  journal = {BMJ Case Rep},
  year = {2012},
  volume = {7},
  doi = {http://dx.doi.org/10.1136/bcr.11.2011.5196}
}
Nair PP, Khilari M, Peddawad D, Chandrashekhar L Meningeal calcification in basal cell nevus syndrome 2013 BMJ Case Rep.
Vol. 28 
article DOI  
BibTeX:
@article{NairPP2013,
  author = {Nair PP, Khilari M, Peddawad D, Chandrashekhar L.},
  title = {Meningeal calcification in basal cell nevus syndrome},
  journal = {BMJ Case Rep.},
  year = {2013},
  volume = {28},
  doi = {http://dx.doi.org/10.1136/bcr-2013-200545}
}
Nair V, Singh S, Gupta YK Evaluation of disease modifying activity of Coriandrum sativum in experimental models. 2012 Indian J Med Res
Vol. 135:240-5., pp. 240-5 
article  
Abstract: BACKGROUND & OBJECTIVES:
Coriandrum sativum (CS), has been widely used in traditional systems of medicine for treatment of rheumatoid arthritis. However, the mechanism of action for its antiarthritic effects is not clearly known. Therefore, the present study was carried out to evaluate the antiarthritic activity of CS in rats in two experimental models.
METHODS:
The antiarthritic activity of CS seed hydroalcoholic extract (CSHE) was evaluated in adult Wistar rats by using two experimental models, viz. formaldehyde and Complete Freund's adjuvant (CFA) induced arthritis. The expression of pro-inflammatory cytokines (predominantly contributed by macrophages) was also evaluated. TNF- ? level was estimated in serum by ELISA method. TNF-R1, IL-1 ? and IL-6 expression in the synovium was analysed by immunohistochemistry.
RESULTS:
CSHE produced a dose dependent inhibition of joint swelling as compared to control animals in both, formaldehyde and CFA induced arthritis. Although there was a dose dependent increase in serum TNF-? levels in the CSHE treated groups as compared to control, the synovial expression of macrophage derived pro-inflammatory cytokines/cytokine receptor was found to be lower in the CSHE treated groups as compared to control.
INTERPRETATION & CONCLUSIONS:
Our results demonstrate that the antiarthritic activity of CSHE may be attributed to the modulation of pro-inflammatory cytokines in the synovium. In further studies CSHE could be explored to be developed as a disease modifying agent in the treatment of RA.
BibTeX:
@article{NairV2012,
  author = {Nair V, Singh S, Gupta YK},
  title = {Evaluation of disease modifying activity of Coriandrum sativum in experimental models.},
  journal = {Indian J Med Res},
  year = {2012},
  volume = {135:240-5.},
  pages = {240-5}
}
Nalini A, Gayathri N, Nishino I, Hayashi YK GNE myopathy in India 2013 Neurol India.
Vol. 61(4), pp. 371-4 
article DOI  
Abstract: BACKGROUND:
GNE myopathy is a clinicopathologically distinct distal myopathy with autosomal-recessive inheritance. The GNE gene mutations are known to cause this form of distal myopathy
MATERIALS AND METHODS:
Over the last 6 years, a total of 54 patients from 48 families were diagnosed to have GNE myopathy based on the clinical and histopathological findings. We have reported on 23 cases earlier and from this cohort 12 patients from 11 families underwent genetic testing for GNE mutation.
RESULTS:
Nine patients belonging to eight families were confirmed as GNE myopathy by genetic analysis. There were six women and three men. Mean age of onset was 26.7 ± 5.47 years (20-36 years) and mean age at clinical examination was 32.3 ± 4.2 years (28-39 years). Mean duration of the illness was 5.7 ± 4.7 years (1-14 years). All had characteristic clinical features of progressive weakness and wasting of the anterior part of leg muscles, adductors of thighs and hamstrings with relative sparing of the quadriceps muscles. Biopsy from the tibialis anterior muscles revealed the presence of rimmed vacuoles. Mutation analysis of the GNE gene revealed that c. 2086G > A (p.Val696Met) change was common in our series like Thailand and six of eight families carried this mutation, heterozygously.
CONCLUSION:
These results show the presence of a common mutation in GNE gene in Southeast Asia.
BibTeX:
@article{NaliniA2013,
  author = {Nalini A, Gayathri N, Nishino I, Hayashi YK.},
  title = {GNE myopathy in India},
  journal = {Neurol India.},
  year = {2013},
  volume = {61(4)},
  pages = {371-4},
  doi = {http://dx.doi.org/10.4103/0028-3886.117609}
}
Nanjappa V, Suchismitha R, Devaraj HS, Shah MB, Anan A, Rahim SN Vulval tuberculosis - an unusual presentation of disseminated tuberculosis. 2012 J Assoc Physicians IndiaAssoc Physicians India.
Vol. 60, pp. 49-52 
article  
Abstract: Extrapulmonary involvement can occur in isolation or along with a pulmonary focus as in the case of patients with disseminated tuberculosis. Vulval TB is very rare and the presentation can be quite variable, and may be misdiagnosed as sexually transmitted disease. We herein report a young lady with disseminated TB presenting as Vulval TB
BibTeX:
@article{NanjappaV2012,
  author = {Nanjappa V, Suchismitha R, Devaraj HS, Shah MB, Anan A, Rahim SN.},
  title = {Vulval tuberculosis - an unusual presentation of disseminated tuberculosis.},
  journal = {J Assoc Physicians IndiaAssoc Physicians India.},
  year = {2012},
  volume = {60},
  pages = {49-52}
}
Narayanan D, Anitha A, Jayakumar R, Chennazhi KP PTH 1-34 loaded thiolated chitosan nanoparticles for osteoporosis: oral bioavailability and anabolic effect on primary osteoblast cells. 2014 J Biomed Nanotechnol.
Vol. 10(1), pp. 166-78. 
article  
Abstract: In this work, biocompatible and mucoadhesive thiolated chitosan (TCS) was used in the preparation of oral nanoformulation of human parathyroid hormone 1-34 (PTH 1-34) as an alternative patient compliant route in treating osteoporosis. PTH 1-34 loaded thiolated chitosan nanoparticles (TCS-PTH 1-34 NPs) size, morphology and interaction was analysed by DLS, SEM and FTIR respectively. TCS-PTH 1-34 NPs (90-100 nm) with 60% encapsulation efficiency was subjected to an in vitro release in simulated rat body fluids. TCS-PTH 1-34 NP's treated human primary osteoblast cells (HOB) upon PTH 1-34 receptor activation, produced second messenger-cAMP which down stream stimulated, production of bone specific alkaline phosphatase, osteocalcin and even enhanced the intracellular calcium uptake. These data substantiates the anabolic effect and bioactivity of the PTH 1-34 released from the TCS-PTH 1-34 NPs. Bare PTH 1-34 failed to reach the systemic circulation following oral dosage in rats whereas TCS-PTH 1-34 NPs showed an oral bioavailability of 0.075 microg PTH 1-34 throughout 48 h which is indeed a significant improvement in the half life of this peptide. TSC-PTH 1-34 NPs have released an advantageous anabolic dose of the peptide in blood that is suited for the treatment of osteoporosis. NIR image of gastrointestinal transit of ICG conjugated nanoformulation supports and justifies this significant finding. These results cumulatively point out that TCS NPs loaded with PTH 1-34 is efficient in orally delivering the peptide. This route of administration has increased its half life and improved the bioavailability compared to the bare peptide that is delivered systemically for treating osteoporosis.
BibTeX:
@article{NarayananD2014,
  author = {Narayanan D, Anitha A, Jayakumar R, Chennazhi KP},
  title = {PTH 1-34 loaded thiolated chitosan nanoparticles for osteoporosis: oral bioavailability and anabolic effect on primary osteoblast cells.},
  journal = {J Biomed Nanotechnol.},
  year = {2014},
  volume = {10(1)},
  pages = {166-78.}
}
Narayanan D, Anitha A, Jayakumar R, Nair SV, Chennazhi KP Synthesis, characterization and preliminary in vitro evaluation of PTH 1-34 loaded chitosan nanoparticles for osteoporosis. 2012 J Biomed Nanotechnol.
Vol. 8(1), pp. 98-106 
article  
Abstract: Human Parathyroid hormone 1-34 (PTH1-34) loaded chitosan nanoparticles (PTH 1-34 chitosan nanoparticles) via simple ionic gelation technique were prepared which can improve the bioavailability and half-life of the peptide. Chitosan nanoparticles and PTH 1-34 chitosan nanoparticles were synthesised and characterized by DLS, SEM, AFM, FT-IR and TG/DTA. Chitosan nanoparticles (40-60 nm) and PTH 1-34 chitosan nanoparticles (60-80 nm) with zeta potential of +60 and +40 mV respectively were subjected to haemolysis assay and tested for agglomeration in blood. MTT and LDH was performed assay using Saos-2, UMR 106, L929, NIH3T3. The in vitro peptide release profile at pH 7.5 for 144 h was quantified using PTH 1-34 ELISA Kit. Effect of released PTH 1-34 on Saos-2 was determined with ALP and BCA assay. These preliminary results pave way for the prospective use of such a carrier for the delivery of PTH 1-34 by multiple routes for the benefit of patients undergoing treatment for osteoporosis.
BibTeX:
@article{NarayananD2012,
  author = {Narayanan D, Anitha A, Jayakumar R, Nair SV, Chennazhi KP.},
  title = {Synthesis, characterization and preliminary in vitro evaluation of PTH 1-34 loaded chitosan nanoparticles for osteoporosis.},
  journal = {J Biomed Nanotechnol.},
  year = {2012},
  volume = {8(1)},
  pages = {98-106}
}
Raman P Physiologic neuromuscular dental paradigm for the diagnosis and treatment of temporomandibular disorders. 2014 J Calif Dent Assoc.
Vol. 42(8), pp. 563-71 
article  
Abstract: Shifting from traditional anatomical/mechanistic models, the physiologic neuromuscular dentistry (PNMD) paradigm acknowledges the primacy of physiology in shaping and controlling anatomy in a functioning human body. Occlusal disharmony from mandibular discrepancy to cranium leads to temporomandibular disorders(TMD), which is a disease of musculoskeletal imbalance in the postural chain exceeding the individual's physiologic adaptive capacity. To diagnose optimal craniomandibular alignment, PNMD is guided by real-time objective physiologic data such as electromyography (EMG).
BibTeX:
@article{P.2014,
  author = {Raman P.},
  title = {Physiologic neuromuscular dental paradigm for the diagnosis and treatment of temporomandibular disorders.},
  journal = {J Calif Dent Assoc.},
  year = {2014},
  volume = {42(8)},
  pages = {563-71}
}
Parida PK, Surianarayanan G, Ganeshan S, Saxena SK Pott's puffy tumor in pediatric age group: a retrospective study. 2012 Int J Pediatr Otorhinolaryngol
Vol. 76(9), pp. 1274-7 
article DOI  
Abstract: •OBJECTIVE:
•To study the etiology, clinical features and treatment outcomes of pediatric Pott's puffy tumor (PPT).
•METHODS:
•This retrospective study was carried by reviewing medical case record of pediatrics PPT cases admitted to our hospital from January 2010 to august 2011. Data regarding the patient's demographic details, presenting symptoms and signs, etiology, laboratory findings, imaging findings, management, complications and outcomes of treatment were collected and analyzed.
•RESULTS:
•A total of five cases of PPT were found. Three were male and two were female with a mean age of 11.6 years. All patients presented with headache, fever and tender forehead swelling. Nasal polyps and discharging sinuses over forehead were present in one case and one case had preseptal orbital cellulites in addition to PPT. None of the patient had intracranial complications. Three cases (60%) were secondary to acute frontal sinusitis, one case was as complication of chronic sinusitis and one case was because of trauma. Contrast enhanced Computerized tomography (CECT) demonstrated features of acute sinusitis in 3 cases, sinonasal polyp in one, fracture of anterior table of frontal bone in one case, subperiosteal collection and erosion of anterior table frontal bone in all cases. All patients required surgical intervention; Endoscopic approach 2 cases (40%), combined approach in 2 cases (40%) and external approach in one case (20%) in addition to aggressive antibiotic treatment. There was purulent discharge in frontal sinuses in all cases. In 2 cases (40%), culture of pus drained during surgery was positive; one case methicillin resistant Staphylococcus aureus sensitive to vancomycin, other Pseudomonas aeruginosa sensitive to ceftazidime and amikacin. All cases improved with treatment. There were no postoperative complications or facial cosmetic deformity except facial scar in three cases. The average hospital stay was two weeks and ranged from 10 days to 21 days. All patients received antibiotics for 6-8 weeks to treat osteomyelitis of the frontal bone. The average length of follow up was 9 months (range 6-18 months). All patient are doing well and are under regular follow up.
•CONCLUSIONS:
•PPT is a complicated infection of frontal sinusitis and trauma that requires broad spectrum antibiotics and surgical treatment. Diagnosis is made by high clinical suspicion of this condition and confirmed by CECT. Early treatment results in favorable outcomes and decreases the risk of further complications.
BibTeX:
@article{ParidaPK2012,
  author = {Parida PK, Surianarayanan G, Ganeshan S, Saxena SK.},
  title = {Pott's puffy tumor in pediatric age group: a retrospective study.},
  journal = {Int J Pediatr Otorhinolaryngol},
  year = {2012},
  volume = {76(9)},
  pages = {1274-7},
  doi = {http://dx.doi.org/10.1016/j.ijporl.2012.05.018}
}
Patil MB, Patil SM Facio-auriculo-vertebral sequence in association with congenital hypoparathyroidism. 2012 Indian Pediatr
Vol. 49(8), pp. 670-2 
article  
Abstract: Although, Facio-auriculo-vertebral sequence (FAVS) is a well recognized condition with cranio-facial, ocular and vertebral anomalies, extreme variability of expression is characteristic. Association of cardiac, CNS, lungs, kidneys and limb defects are described. We report a neonatal case with FAVS in association with congenital hypoparathyroidism.
BibTeX:
@article{PatilMB2012,
  author = {Patil MB, Patil SM.},
  title = {Facio-auriculo-vertebral sequence in association with congenital hypoparathyroidism.},
  journal = {Indian Pediatr},
  year = {2012},
  volume = {49(8)},
  pages = {670-2}
}
Patil PL, Rao BV Sickle cell disease with osteogenesis imperfecta. 2013 J Assoc Physicians India
Vol. Jun;61(6), pp. 415-7. 
article  
Abstract: A 16 yr old female presented with generalized weakness and easy fatigability since 2 months. Her medical history included that she had sickle cell disease (ss pattern) on regular treatment. She denied smoking and consumption of alcohol. She had adequate calcium intake and her menstrual history was non-contributory. History of right tibial diaphysial fracture 1 year back followed by refracture at the same site 6 months later. On examination patient was 146 cm tall & weighed 48 kg. She had pallor, blue-grey sclera,scar mark of previous operation on right leg. Her mother and two maternal aunts also had blue-gray sclera. She had normal dentition and other systems were normal. Radiological screening showed diffuse osteopenia of all visualized skeleton, biconcave vertebral bodies in lumbar spine, Old healed fracture of right tibial diaphysis with intra-medullary nail in situ, wormian bones seen along the lambdoid suture, old healed fracture with sclerosis noted involving diaphysis of first metatarsal. Secondary causes of osteoporosis were ruled out. Skeletal involvement is sickle cell disease is usually in the form of avascular necrosis, dactylitis, joint effusions or osteomyelitis however osteoporosis and long bone fractures are not known in sickle cell disease. Owing to high index of suspicion a diagnosis of osteogenesis imperfecta was pursued, since the patient presented at 16 years age with relatively minor symptoms type 1A osteogenesis imperfecta (mildest form) was established. Systemic screening for disease complications included osteopontogram, audiogram and consultation with ophthalmologist and geneticist. Therapy with calcium and vit D was initiated and an in depth discussion regarding biphosphonates was pursued. Anaemia was corrected with blood transfusion and treatment of sickle cell disease was continued. Family screening was offered. Fractures particularly adults older than 45 are associated with osteoporosis. This case illustrates the importance of family history, fracture history and clinical correlation when assessing patients with osteoporosis. Mild OI most often presents after infancy and should be considered whenever children or adults have recurrent fractures. Early diagnosis of this disease by family physicians will enable initiation of therapy as well as patients education regarding management of modifiable risk factors linked with osteoporosis (e.g. diet, smoking, alcohol). Genetic counseling and family screening could also be offered.
BibTeX:
@article{PatilPL2013,
  author = {Patil PL, Rao BV.},
  title = {Sickle cell disease with osteogenesis imperfecta.},
  journal = {J Assoc Physicians India},
  year = {2013},
  volume = {Jun;61(6)},
  pages = {415-7.}
}
Prakash Singh S, Tanwar Y, Habib M, Jaiswal A, Lal H Boomerang proximal tibial osteotomy for the treatment of severe varus gonarthrosis. 2013 Int Orthop
Vol. 37(10), pp. :2093 
article DOI  
BibTeX:
@article{PrakashSinghS2013,
  author = {Prakash Singh S, Tanwar Y, Habib M, Jaiswal A, Lal H.},
  title = {Boomerang proximal tibial osteotomy for the treatment of severe varus gonarthrosis.},
  journal = {Int Orthop},
  year = {2013},
  volume = {37(10)},
  pages = {:2093},
  doi = {http://dx.doi.org/10.1007/s00264-013-2056-5}
}
Premkumar M, Dhanwal DK, Mathews S, Garg A, Sahoo S, Mahamine K, Samad S Avascular osteonecrosis of femoral head in a postoperative patient of pituitary Cushing's disease. 2013 J Assoc Physicians India
Vol. 61(6), pp. 413-5 
article  
Abstract: We describe a rare association of Cushing's disease causing avascular osteonecrosis of the femoral head in a patient with operated pituitary macroadenoma. Avascular necrosis of the femoral head (AVN) is not a common cause of musculoskeletal disability. Though AVN of the hip is a well-recognized complication of steroid treatment, it is rare in cases of endogenous hypercortisolism. To our knowledge, only 16 patients with AVN, associated with endogenous Cushing's syndrome (CS), have been documented in the medical literature. AVN associated with glucocorticoid use is more likely to manifest as bilateral disease than either idiopathic AVN or ethanol-associated AVN. We describe a 26-year-old woman who was diagnosed with Cushing's disease in 2007 and operated in the same year for an ACTH secreting pituitary adenoma, who was consequently given replacement dose steroid therapy for post operative panhypopituitarism. During follow up, she complained of bilateral hip pain and difficulty in ambulation. Magnetic resonance imaging showed multiple bony infarcts in the proximal femur and distal femur with femoral head collapse fractures bilaterally, consistent with AVN. She further underwent decompression surgery on bilateral hip joints. This case illustrates that AVN, an orthopaedic emergency, can be an alarming manifestation of Cushing's disease.
BibTeX:
@article{PremkumarM2013,
  author = {Premkumar M, Dhanwal DK, Mathews S, Garg A, Sahoo S, Mahamine K, Samad S.},
  title = {Avascular osteonecrosis of femoral head in a postoperative patient of pituitary Cushing's disease.},
  journal = {J Assoc Physicians India},
  year = {2013},
  volume = {61(6)},
  pages = {413-5}
}
Rahman MT, Myles A, Gaur P, Misra R, Aggarwal A TLR4 endogenous ligand MRP8/14 level in enthesitis-related arthritis and its association with disease activity and TLR4 expression. 2014 Rheumatology (Oxford)
Vol. 53(2), pp. 270-4 
article DOI  
Abstract: OBJECTIVE:
Enthesitis-related arthritis (ERA) is an inflammatory disease of childhood that lacks autoantibodies. Overexpression of surface-expressed Toll-like receptors (TLRs) has been found in ERA. Myeloid-related proteins (MRPs) 8 and 14 are calcium binding proteins that act as an endogenous ligand of TLR4. MRP8/14 levels are elevated in patients with systemic-onset arthritis. Thus we studied the role of MRP8/14 in ERA.
METHODS:
The study enrolled patients with ERA. Plasma and SF levels of MRP8/14 were measured by ELISA and TLR4 expression on peripheral blood and SF monocytes was measured by two-colour flow cytometry. Control plasma samples were collected from 48 blood bank donors.
RESULTS:
Of the 69 patients, 67 were male, with a mean age of 15.2 (s.d. 2.7) years and a disease duration of 5 (s.d. 3) years. Median plasma levels of MRP8/14 were higher in patients (10 862.3 ng/ml) than controls (4426.1 ng/ml, P < 0.0001). Patients with active disease (11 669.5 ng/ml) had higher levels as compared with inactive disease (4421.8 ng/ml, P < 0.0001). Plasma MRP8/14 levels decreased on follow-up after 3 months only in patients who responded to treatment (P = 0.012). MRP8/14 levels were negatively correlated with the frequency of CD14(+)TLR4(+) cells (r = -0.372, P = 0.02). MRP8/14 levels were higher in SF as compared with plasma (15 858.45 ng/ml, P = 0.024). The frequency of CD14(+)TLR4(+) cells was higher in SF as compared with peripheral blood.
CONCLUSION:
MRP8/14 levels are increased in the plasma of ERA patients and are higher in those with active disease and the levels decrease in patients who respond to treatment, suggesting that it may be a good biomarker during follow-up.
BibTeX:
@article{RahmanMT2014,
  author = {Rahman MT, Myles A, Gaur P, Misra R, Aggarwal A.},
  title = {TLR4 endogenous ligand MRP8/14 level in enthesitis-related arthritis and its association with disease activity and TLR4 expression.},
  journal = {Rheumatology (Oxford)},
  year = {2014},
  volume = {53(2)},
  pages = {270-4},
  doi = {http://dx.doi.org/10.1093/rheumatology/ket375}
}
Rajapurkar M, Thankappan K, Sampathirao LM, Kuriakose MA, Iyer S Oncologic and functional outcome of the preserved eye in malignant sinonasal tumors. 2013 Head Neck.
Vol. 35(10), pp. 1379-84 
article DOI  
Abstract: BACKGROUND:
The purpose of this study was to analyze the oncologic and functional outcomes of the preserved eye in malignant sinonasal tumors with orbital involvement.
METHODS:
In a retrospective study of 19 consecutive patients who underwent craniofacial resection or maxillectomy with preservation of orbital contents and adjuvant radiotherapy, the oncological outcome in terms of local recurrence and survival was analyzed. The functional outcome in the preserved eye was analyzed for the cases that did not recur in the orbit.
RESULTS:
Nineteen patients were analyzed for their oncologic and functional outcomes. Fifteen patients underwent immediate reconstruction of the orbital support. Eight patients had local recurrences; 11 patients were disease free at the end of the follow-up. Squamous cell carcinoma has a high propensity for local recurrences (ie, 5 of 8 local recurrences were squamous cell carcinoma). Sixteen patients, in whom a satisfactory orbital tumor clearance was obtained, remained recurrence free in the orbit. All the preserved eyes retained adequate function after adjuvant radiotherapy.
CONCLUSIONS:
Adequate local control with preserved visual function can be obtained with surgery and adjuvant radiation in appropriately selected malignant sinonasal tumors with orbital involvement. The preserved eye, if reconstructed appropriately, maintains good overall function with acceptable morbidity.
BibTeX:
@article{RajapurkarM2013,
  author = {Rajapurkar M, Thankappan K, Sampathirao LM, Kuriakose MA, Iyer S.},
  title = {Oncologic and functional outcome of the preserved eye in malignant sinonasal tumors.},
  journal = {Head Neck.},
  year = {2013},
  volume = {35(10)},
  pages = {1379-84},
  doi = {http://dx.doi.org/10.1002/hed.23137}
}
Rajgopal A, Vasdev A, Chidgupkar AS, Dahiya V, Tyagi VC Mid-term results of rotating hinge knee prostheses. 2012 Acta Orthop Belg.
Vol. 78(1), pp. 61-7 
article  
Abstract: Between December 2002 and December 2007, we retrospectively assessed the mid term results of the Nexgen rotating hinge prosthesis in the hands of a single surgeon in difficult primary and complex revision situations. Forty four patients (46 knees) were included in the study: they were followed for an average of 62 months. Knee Society knee score improved from a preoperative mean value of 47 to a mean value of 81 at follow-up (p < 0.05) whereas the mean function score improved from 17 (0-40) to 67.5 (0-90) at follow-up (p < 001). Mean flexion range improved from 65 degrees to 96 degrees at follow-up (p < 0.05). In conclusion, rotating hinge knees gave satisfactory results in difficult revision situations associated with major bone loss, instability or periprosthetic fracture. They also provided satisfactory results in selected cases of advanced primary osteoarthritis.
BibTeX:
@article{RajgopalA2012,
  author = {Rajgopal A, Vasdev A, Chidgupkar AS, Dahiya V, Tyagi VC},
  title = {Mid-term results of rotating hinge knee prostheses.},
  journal = {Acta Orthop Belg.},
  year = {2012},
  volume = {78(1)},
  pages = {61-7}
}
Rao S Decompression as a treatment for odontogenic cystic lesions of the jaw. 2014 J Oral Maxillofac Surg.
Vol. 72(7), pp. 1231 
article DOI  
BibTeX:
@article{RaoS2014,
  author = {Rao S, Rao S},
  title = {Decompression as a treatment for odontogenic cystic lesions of the jaw.},
  journal = {J Oral Maxillofac Surg.},
  year = {2014},
  volume = {72(7)},
  pages = {1231},
  doi = {http://dx.doi.org/10.1016/j.joms.2014.03.035}
}
Ravindran V, Jadhav R The effect of rheumatoid arthritis disease education on adherence to medications and followup in Kerala, India. 2013 J Rheumatol.
Vol. 40(8), pp. 1460-1 
article DOI  
BibTeX:
@article{RavindranV2013,
  author = {Ravindran V, Jadhav R.},
  title = {The effect of rheumatoid arthritis disease education on adherence to medications and followup in Kerala, India.},
  journal = {J Rheumatol.},
  year = {2013},
  volume = {40(8)},
  pages = {1460-1},
  doi = {http://dx.doi.org/10.3899/jrheum.130350}
}
Revannasiddaiah S, Gupta MK, Rastogi M, Kesari AA, Seam RK, Gupta M, Chauhan S, Madabhavi I Dermatomyositis and chest radiography leading to the diagnosis of lung cancer and subsequent confusions in staging due to the presence of tuberculosis. 2012 BMJ Case Rep.
Vol. 2 
article DOI  
Abstract: This clinical scenario describes dermatomyositis as a presenting feature of carcinoma of the lung. However, the coincident existence of tuberculosis in the opposite lung gave rise to a false impression of contralateral lung metastasis and hence confusions with regard to staging ensued, which were clarified after further investigation confirmed a unilateral lung adenocarcinoma and contralateral tuberculosis. The patient was initiated on oral antiepidermal growth factor receptor therapy with erlotinib, as well as on multi-drug therapy for tuberculosis. This report intends to illustrate that paraneoplastic syndromes such as dermatomyositis can be the presenting feature of lung cancer, and also that the co-incident presence of carcinoma and tuberculosis can cause confusions with regard to staging and management.
BibTeX:
@article{RevannasiddaiahS2012,
  author = {Revannasiddaiah S, Gupta MK, Rastogi M, Kesari AA, Seam RK, Gupta M, Chauhan S, Madabhavi I.},
  title = {Dermatomyositis and chest radiography leading to the diagnosis of lung cancer and subsequent confusions in staging due to the presence of tuberculosis.},
  journal = {BMJ Case Rep.},
  year = {2012},
  volume = {2},
  doi = {http://dx.doi.org/10.1136/bcr.01.2012.5585}
}
Sabarinath VP, Radhakrishnan V, Hazarey PV, Ravindran S Alternative approaches to managing the cleft alveolus. 2013 J Clin Pediatr Dent.
Vol. 38(1), pp. 89-93 
article  
Abstract: The cleft alveolus component of the oral cleft deformity is addressed with a separate surgical stage. Several host and operator related factors affect the surgical outcome. When factors that increase the likelihood of secondary alveolar bone graft failure are identified, alterative methods like dentoalveolar distraction (DAD) may be employed. In infants, molding of the alveolar segments is possible and when a synergistic surgical approach is used, the possibility of successful alveolar cleft repair is increased. The authors present two case reports wherein the use of nasoalveolar molding (NAM) and DAD helped to tackle the alveolar cleft deformity.
BibTeX:
@article{SabarinathVP2013,
  author = {Sabarinath VP, Radhakrishnan V, Hazarey PV, Ravindran S.},
  title = {Alternative approaches to managing the cleft alveolus.},
  journal = {J Clin Pediatr Dent.},
  year = {2013},
  volume = {38(1)},
  pages = {89-93}
}
Sachdev M, Rastogi A, Singh A, Kumar K, Kapoor S, Bansal Y, Goel S Phenotypic overlap between Blepharo-naso-facial syndrome and Nablus mask-like syndrome. Report from the first Indian family. 2013 Ophthalmic Genet.
Vol. 34(1-2), pp. 65-8 
article DOI  
Abstract: We describe two siblings with epiphora, telecanthus, expressionless face, thick facial skin, bulky nose and profound sensorineural hearing loss. Constellation of these features presented a phenotypic overlap with Blepharo-naso-facial syndrome (BNFS) and Nablus mask-like syndrome (NMLS). They in addition had posterior helical pits. The molecular basis of NMLS is known, while BNFS remains an elusive disorder. We report the first Indian family with features having significant overlap between the two but we attempt to summarize the frequency of reported features and bring out the most consistent features for these two syndromes for the treating clinician.
BibTeX:
@article{SachdevM2013,
  author = {Sachdev M, Rastogi A, Singh A, Kumar K, Kapoor S, Bansal Y, Goel S.},
  title = {Phenotypic overlap between Blepharo-naso-facial syndrome and Nablus mask-like syndrome. Report from the first Indian family.},
  journal = {Ophthalmic Genet.},
  year = {2013},
  volume = {34(1-2)},
  pages = {65-8},
  doi = {http://dx.doi.org/10.3109/13816810.2012.695423}
}
Salunke P, Futane S, Vaiphei K Posterior bilateral supernumerary atlantoaxial facets: true or false joint? 2013 Spine (Phila Pa 1976).
Vol. 1;38(25), pp. E1633-5 
article DOI  
Abstract: Pneumosinus dilatans describes an abnormal dilation of one or more paranasal sinuses without radiological evidence of localised bone destruction, hyperostosis or mucous membrane thickening. Dilation of mastoid air cells also occurs rarely along with involvement of paranasal sinuses. This rare combination of unknown aetiology was reported in two cases in the literature and termed 'Pneumosinus Dilatans Multiplex' (PSDM). It is usually asymptomatic, and is detected incidentally on plain radiography, CT or MRI. If left untreated, it can further erode the bone leading to complications such as facial asymmetry, neurological disorders and pathological fractures. The aetiology of the condition remains obscure. Various hypotheses proposed are the presence of gas-forming microorganisms, spontaneous drainage of a mucocele, the presence of a one-way valve, dysregulation of hormonal levels leading to a disturbance of osteoblastic and osteoclastic activity. This paper describes a case of PSDM possibly secondary to hormonal disturbance.
BibTeX:
@article{SalunkeP2013,
  author = {Salunke P, Futane S, Vaiphei K.},
  title = {Posterior bilateral supernumerary atlantoaxial facets: true or false joint?},
  journal = {Spine (Phila Pa 1976).},
  year = {2013},
  volume = {1;38(25)},
  pages = {E1633-5},
  doi = {http://dx.doi.org/10.1097/BRS.0b013e3182a8a603}
}
Santra G, Banerjee S, Sarkar RN Multiple epiphyseal dysplasia. 2013 J Assoc Physicians India
Vol. 61(6), pp. 408-9. 
article  
BibTeX:
@article{SantraG2013,
  author = {Santra G, Banerjee S, Sarkar RN.},
  title = {Multiple epiphyseal dysplasia.},
  journal = {J Assoc Physicians India},
  year = {2013},
  volume = {61(6)},
  pages = {408-9.}
}
Sardana K, Sagar V Black heel (talon noir) associated with a viral exanthem. 2013 Indian Pediatr.
Vol. 50(10), pp. 982 
article  
BibTeX:
@article{SardanaK2013,
  author = {Sardana K, Sagar V.},
  title = {Black heel (talon noir) associated with a viral exanthem.},
  journal = {Indian Pediatr.},
  year = {2013},
  volume = {50(10)},
  pages = {982}
}
Sarkar A, Dutta S, Bal K, Biswas J Handedness may be related to variations in palmar arterial arches in humans. 2012 Singapore Med J
Vol. 53(6), pp. 409-12 
article  
Abstract: •INTRODUCTION:
•The superficial and deep palmar arterial arches are the main sources of blood supply to all structures in the human hand, and variations in these arterial arches are quite common. Although several studies have reported diameters and variations of these arches, to the authors' knowledge, no study has correlated such changes to handedness in adults. It is likely that dominance may play a role in arterial variations, such as those seen in the diameter or number of arteries formed in the palmar arches, much like in other areas of the human body. This cadaver study was conducted to determine any such association.
•METHODS:
•42 formalin-fixed hands were dissected to expose the superficial and deep palmar arches. These arches were then thoroughly examined for any variations between the dominant and non-dominant hands. All cadavers were noted to be right-handed as per hospital records.
•RESULTS:
•19 complete superficial arterial arches (right hand 14; left hand 5) were found in the 42 hands dissected.
•CONCLUSION:
•Most complete superficial palmar arches were found in the dominant hand of the cadavers studied, and therefore, handedness may have a role to play in determining palmar arterial arch variations in humans. Due to dominance or handedness, some arteries may likely persist into adulthood while others may become obliterated, thus leading to variations. Dissection of foetal hands may help to shed more light on the persistence or obliteration of various arteries after birth. Knowledge of such variations may prove helpful for surgeons during hand surgeries.
BibTeX:
@article{SarkarA2012,
  author = {Sarkar A, Dutta S, Bal K, Biswas J},
  title = {Handedness may be related to variations in palmar arterial arches in humans.},
  journal = {Singapore Med J},
  year = {2012},
  volume = {53(6)},
  pages = {409-12}
}
Sharma A, Sane H, Paranjape A, Bhagawanani K, Gokulchandran N, Badhe P Autologous bone marrow mononuclear cell transplantation in Duchenne muscular dystrophy - a case report. 2014 Am J Case Rep
Vol. 28;15, pp. 128-34 
article DOI  
Abstract: •PATIENT:
•Male, 9 FINAL DIAGNOSIS: Duchenne muscular dystrophy Symptoms: Hyporeflexia • hypotonia • weaknes of lower limbs
•MEDICATION:
•- Clinical Procedure: - Specialty: Neurology.
•OBJECTIVE:
•Congenital defects/diseases.
•BACKGROUND:
•Duchenne muscular dystrophy (DMD) is a fatal, genetic, progressive, degenerating muscle disorder. Current treatment options are palliative. Newer options of cellular therapy promise to alter the disease process. Preclinical studies have successfully tested myogenic, neurogenic potential and dystrophin expression of bone marrow mononuclear cells.
•CASE REPORT:
•We treated a 9-year-old boy suffering from DMD with serial autologous bone marrow mononuclear cell transplantations followed by multidisciplinary rehabilitation. Brooke-Vignos score was 10 and he was wheelchair-bound. Over 36 months, gradual progressive improvement was noticed in muscle strength, ambulation with assistive devices, fine motor movements, Brooke-Vignos score, and functional independence measure score. Nine months after the transplantation, electromyography findings showed development of new normal motor unit potentials of the vastus medialis muscle.
•CONCLUSIONS:
•Magnetic resonance imaging scan of musculoskeletal systems showed no increase in fatty infiltration. This case report provides early investigative findings or the restorative effects of cellular therapy in DMD.
BibTeX:
@article{SharmaA2014,
  author = {Sharma A, Sane H, Paranjape A, Bhagawanani K, Gokulchandran N, Badhe P},
  title = {Autologous bone marrow mononuclear cell transplantation in Duchenne muscular dystrophy - a case report.},
  journal = {Am J Case Rep},
  year = {2014},
  volume = {28;15},
  pages = {128-34},
  doi = {http://dx.doi.org/10.12659/AJCR.890078}
}
Shashikanth YK, Katti SM, Mallapur MD Morbidity pattern in foundry workers--a cross-sectional study in an urban area of north Karnataka. 2013 J Indian Med Assoc.
Vol. 111(9):, pp. 595-8. 
article  
Abstract: Foundry industry which is a well established in India employs many workers. These workers are exposed to metal dusts, metal fumes, chemicals, heat and high temperature. To determine the morbidity pattern in foundry workers, a cross-sectional study was conducted in the semi-urban area of Belgaum in Karnataka. All the workers excluding the administrative staff working in the foundries in the specified area were included in the study. A structured questionnaire was used to collect the data. Thorough physical examination was carried out to find out existing morbidities followed by spirometry test to determine their lung function profile. Altogether 498 foundry workers participated in the study. More than 50% of them were working for five years and above. Most of the workers (91.57%) were not using any kind of personal protective devices and 38.55% were smokers. About 68.50% workers had some kind of morbidity. Respiratory system (18.10%) was involved in most of those with morbidities. Chronic bronchitis was the leading morbidity in these workers. There was an association between chronic bronchitis with increasing age of the workers, the number of years they were working in foundries and their smoking habits, which was statistically significant. Foundry workers are exposed to various risk factors like metal dusts, metal fumes and Chemicals which may affect their health. They suffer from various morbidities, particularly respiratory problems which needs periodic health examination. Personal protective devices use should be made compulsory in these workers.
BibTeX:
@article{ShashikanthYK2013,
  author = {Shashikanth YK, Katti SM, Mallapur MD.},
  title = {Morbidity pattern in foundry workers--a cross-sectional study in an urban area of north Karnataka.},
  journal = {J Indian Med Assoc.},
  year = {2013},
  volume = {111(9):},
  pages = {595-8.}
}
Sikri V, Sobti S Askin tumour: a rare thoracopulmonary tumour in adults. 2013 Indian J Chest Dis Allied Sci.
Vol. 55(4), pp. 233-5 
article  
Abstract: Askin tumour, a primitive neuroectodermal tumour of the thoracopulmonary region, is a rare tumour presenting in childhood. Its presentation in adults is rare. We report a case of an Askin tumour in an adult patient who presented to us with worsening breathlessness and vague chest pain. Investigations including immunohistochemistry confirmed the diagnosis of Askin tumour.
BibTeX:
@article{SikriV2013,
  author = {Sikri V, Sobti S.},
  title = {Askin tumour: a rare thoracopulmonary tumour in adults.},
  journal = {Indian J Chest Dis Allied Sci.},
  year = {2013},
  volume = {55(4)},
  pages = {233-5}
}
Singh G, Kumar S, Singh DP, Verma V, Mohammad A A rare case of primary tuberculous osteomyelitis of skull vault. 2014 Indian J Tuberc.
Vol. 61(1), pp. 79-83 
article  
Abstract: In recent years, there has been a substantial increase in number of reports involving uncommon sites involving in tuberculosis. Rise in number of HIV positive patients has made the scenario worse. Calvarial tuberculosis has beenreported very rarely in world literature till now. We are reporting a case of primary tuberculous osteomyelitis of frontal bone in a 15-year-old female. With prompt as well as careful diagnostic workup and treatment, we were able to halt the disease progression and excellent response to treatment was observed in follow up.
BibTeX:
@article{SinghG2014,
  author = {Singh G, Kumar S, Singh DP, Verma V, Mohammad A.},
  title = {A rare case of primary tuberculous osteomyelitis of skull vault.},
  journal = {Indian J Tuberc.},
  year = {2014},
  volume = {61(1)},
  pages = {79-83}
}
Singh K, Kumar R, Shukla A, Phadke SR, Agarwal S Status of 25-hydroxyvitamin D deficiency and effect of vitamin D receptor gene polymorphisms on bone mineral density in thalassemia patients of North India. 2012 Hematology.
Vol. 17(5), pp. 291-6 
article DOI  
Abstract: •BACKGROUND:
•Bone disease comprising of low bone mineral density (BMD), bone pain, and fractures is a characteristic feature of thalassemia. Vitamin D receptors (VDRs - FokI, TaqI, and Bsml) polymorphisms are closely related to low BMD at the lumbar spine and hips which can be used as a useful genetic marker in predicting bone disease in these patients.
•AIM:
•To find out the status of VDRs gene polymorphisms and its effect on osteoporosis in thalassemia patients of North Indian origin.
•MATERIAL AND METHODS:
•BMD was measured in 40 beta-thalassemia major patients by dual-energy X-ray densitometry (DXA). Serum vitamin D levels were estimated by enzyme linked immunosorbant assay. VDR gene polymorphisms (FokI, TaqI, and BsmI) were analyzed by polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) method.
•RESULTS:
•About 80.6% cases were found to be vitamin D deficient. Z score of BMD of lumbar spine and hips were -2.31 ± 1.18 and -2.09 ± 0.89. Osteoporotic lumbar spine was observed in 42.5% cases of thalassemia. A positive correlation of vitamin D level was found with Z score of BMD of lumbar spine (r = 0.398, P value = 0.027). Polymorphisms of FokI and BsmI were found significantly correlated with BMD of lumbar spine. However, no association of BMD was observed with TaqI polymorphism.
•CONCLUSION:
•The present study showed a high prevalence of low BMD in thalassemia, suggesting that they should be targeted for DXA screening and osteoporosis prevention before permanent end organ bone damage occurs. The VDR genotyping can be used as additional test in individuals who are susceptible to osteoporosis so that early preventive measurements can be taken.
BibTeX:
@article{SinghK2012,
  author = {Singh K, Kumar R, Shukla A, Phadke SR, Agarwal S.},
  title = {Status of 25-hydroxyvitamin D deficiency and effect of vitamin D receptor gene polymorphisms on bone mineral density in thalassemia patients of North India.},
  journal = {Hematology.},
  year = {2012},
  volume = {17(5)},
  pages = {291-6},
  doi = {http://dx.doi.org/10.1179/1607845412Y.0000000017}
}
Singh NK, Behera DR, Agrawal A, Singh MN, Kumar V, Godhra M, Gupta A, Yadav DP, Singh U, Pandey LK, Matah M Hospital based prospective longitudinal clinical and immunologic study of 179 patients of primary anti-phospholipid syndrome 2013 Int J Rheum Dis
Vol. 16(5), pp. 547-55 
article DOI  
Abstract: AIM:
To study the clinical and immunological features of primary antiphospholipid syndrome (APS), and to analyze the differences between primary APS and APS associated with autoimmune rheumatic disease (ARD/APS).
METHODS:
This prospective, longitudinal study, carried out from December 2004 to July 2011 included 179 patients with primary APS and 52 patients of ARD/APS diagnosed as per modified 2006 Sapporo's Criteria.
RESULTS:
Out of 179 patients of primary APS, 12 were male and 167 were female. The mean age at the time of study entry was 27 ± 4.33 years. Venous thrombosis was noted in 33 (18.43%) patients. Seventeen patients had deep vein thrombosis and 11 (7.19%) had cortical vein and/or cortical sinus thrombosis. Arterial thrombosis was noted in 19 (10.61%) patients, out of which nine had intracranial arterial thrombosis. Thirty-two (17.85%) had recurrent early fetal losses (< 10 weeks) and 97 (54.18%) had late fetal loss (> 10 weeks). Immunoglobulin G (IgG) and IgM aCLA were present in 141 (78.77%) and 32 (17.87%) patients respectively, whereas lupus anticoagulant was present in 99 (55.3%) patients. In patients with bad obstetric outcome, lupus anticoagulant positivity was significantly more prevalent (P < 0.05) than aCLA positivity. Both venous and arterial thrombosis were significantly more common (P < 0.05) in ARD/APS. However, late fetal loss was significantly more prevalent (P < 0.001) in primary APS.
CONCLUSION:
Primary APS may lead to a variety of clinical manifestations due to venous and/or arterial thrombosis, which at times may be lethal. It is also an important cause of early and late pregnancy loss(es) and other pregnancy morbidities.
BibTeX:
@article{SinghNK2013,
  author = {Singh NK, Behera DR, Agrawal A, Singh MN, Kumar V, Godhra M, Gupta A, Yadav DP, Singh U, Pandey LK, Matah M.},
  title = {Hospital based prospective longitudinal clinical and immunologic study of 179 patients of primary anti-phospholipid syndrome},
  journal = {Int J Rheum Dis},
  year = {2013},
  volume = {16(5)},
  pages = {547-55},
  doi = {http://dx.doi.org/10.1111/1756-185X.12150}
}
Singh VP, Singh RK, Roy D, Baral DD, Vikram M Guidelines and recommendations for studies on psychosocial aspects of patients with craniofacial anomalies. 2012 Mymensingh Med J.
Vol. 21(4), pp. 736-40 
article  
Abstract: In recent years there has been a few numbers of studies on psychosocial aspects of patients with craniofacial anomalies in the world. Current research surrounding psychological aspects of craniofacial anomalies suffers from various inconsistencies as reported by the results which may be due to differences in methodology that has made interpretation of findings very difficult. This article aims to present an evaluation of methodological errors and inconsistent findings in such studies. A thorough search based on electronic data base was done utilizing the following words: "craniofacial anomalies", "psychosocial impact". The resultant studies were evaluated based on the methodology and various lacunae, pitfalls were summed up. The results indicated that most of the studies suffer from various methodological errors. Several guidelines were fabricated so as to minimize error and maximize accuracy. The authors recommend these guidelines for future research design of studies related to psychosocial aspects of patients with craniofacial anomalies.
BibTeX:
@article{SinghVP2012,
  author = {Singh VP, Singh RK, Roy D, Baral DD, Vikram M},
  title = {Guidelines and recommendations for studies on psychosocial aspects of patients with craniofacial anomalies.},
  journal = {Mymensingh Med J.},
  year = {2012},
  volume = {21(4)},
  pages = {736-40}
}
Sira M, Malhotra R Reconstruction of orbital exenteration defects by primary closure using cheek advancement. 2013 Br J Ophthalmol
Vol. 97(2), pp. 201-5 
article DOI  
Abstract: •INTRODUCTION:
•Orbital exenteration is a highly disfiguring procedure which, although providing local control of invasive orbital malignancy also results in marked visual, psychological and social disability. We present three consecutive total exenteration cases over 1 year where all 3, including extended exenteration defects, were repaired by primary closure by way of cheek advancement. This technique may be considered where succinct management with minimal follow-up is required and maybe preferable if considering rapidity of rehabilitation with a short time to fitting definitive prostheses.
•METHODS:
•Retrospective review of three consecutive patients who presented with neglected basal cell carcinoma with orbital invasion and subsequently underwent total orbital exenteration with repair by cheek advancement flap.
•RESULTS:
•All underwent repair with primary skin closure using a cheek advancement flap. Patient 2 developed a small area of central flap dehiscence noted at 2 months with almost complete granulation of the orbital cavity at 3 months. Patients 1, 2 and 3 were fitted with final prosthesis at 7, 6 and 12 months, respectively.
•CONCLUSIONS:
•Reconstruction of the exenterated orbit using cheek advancement represents an evolution of the cervico-facial flap repair. The cheek advancement avoids creating a secondary defect and because it involves less dissection and additional skin incisions, is an easier procedure to perform with fewer facial scars. It does not preclude osseointegration if required at a later date and as such we recommend it as an option in repairing the exenterated orbit.
BibTeX:
@article{SiraM2013,
  author = {Sira M, Malhotra R.},
  title = {Reconstruction of orbital exenteration defects by primary closure using cheek advancement.},
  journal = {Br J Ophthalmol},
  year = {2013},
  volume = {97(2)},
  pages = {201-5},
  doi = {http://dx.doi.org/10.1136/bjophthalmol-2012-301600}
}
Parikh SN Pediatrics. 2013 Orthop Clin North Am
Vol. 44(3):xvii. 
article DOI  
BibTeX:
@article{SN2013,
  author = {Parikh SN},
  title = {Pediatrics.},
  journal = {Orthop Clin North Am},
  year = {2013},
  volume = {44(3):xvii.},
  doi = {http://dx.doi.org/10.1016/j.ocl.2013.05.005}
}
Sodhi KS, Khandelwal N, Virmani V, Das A, Panda N Solitary extramedullary plasmacytoma of the nasal tract: an unusual cause of epistaxis. 2013 Ear Nose Throat J.
Vol. 92(6) 
article  
Abstract: Solitary extramedullary plasmacytoma is a rare hematologic malignancy with nonspecific clinical symptoms and imaging findings. We present a case of this entity that arose in the nasal tract of a 50-year-old man. The tumor was removed surgically, and the patient showed no evidence of recurrence on follow-up. We review the clinical features, imaging and histopathologic findings, and treatment of this rare disease. It is essential for otolaryngologists and head and neck surgeons to be familiar with this entity because total excision and radiation therapy for plasmacytomas can be curative in patients who have no underlying overt plasma cell dyscrasias.
BibTeX:
@article{SodhiKS2013,
  author = {Sodhi KS, Khandelwal N, Virmani V, Das A, Panda N.},
  title = {Solitary extramedullary plasmacytoma of the nasal tract: an unusual cause of epistaxis.},
  journal = {Ear Nose Throat J.},
  year = {2013},
  volume = {92(6)}
}
Sunitha VC, Narayanan S, Nair PP, Prakash ML Left-sided Poland's syndrome in a girl with rare associations like spina bifida and diaphragmatic hernia. 2013 BMJ Case Rep.
Vol. 20 
article DOI  
Abstract: Poland's syndrome is a rare congenital anomaly characterised by partial or complete absence of sternocostal head of pectoralis major muscle and anomalies of ipsilateral hand and digits. Other associated anomalies involving anterior thoracic wall, breast, diaphragm and vertebrae have also been reported in various cases. We report a case of a 10-year-old girl, with features of left-sided Poland's syndrome associated with spina bifida, dextroposition of the heart and left-sided diaphragmatic hernia. These are rare associations of Poland's syndrome. She was investigated with chest X-ray, contrast-enhanced CT of the thorax, ultrasonography of abdomen and echocardiography which helped in arriving at an accurate diagnosis and assessing all the associated abnormalities.
BibTeX:
@article{SunithaVC2013,
  author = {Sunitha VC, Narayanan S, Nair PP, Prakash ML},
  title = {Left-sided Poland's syndrome in a girl with rare associations like spina bifida and diaphragmatic hernia.},
  journal = {BMJ Case Rep.},
  year = {2013},
  volume = {20},
  doi = {http://dx.doi.org/10.1136/bcr-2013-200930}
}
Tadakamadla J, Kumar S, Swapna LA, Reddy S Occupational hazards and preventive practices among students and faculty at a private dental institution in India. 2012 Stomatologija
Vol. 14(1), pp. 28-32 
article  
Abstract: AIMS:
To assess the level of awareness and occupational hazards experienced in addition to preventive measures undertaken by the students and faculty working at a private dental institution in India.
METHODS:
The present study was conducted at a private dental teaching hospital in India using self-administered questionnaires. All the students attending the clinics and the faculty members of the hospital were invited to participate in the study. The final study population consisted of 290 dental professionals. The self-administered questionnaire also included questions on personal information like age, gender, position (student or faculty), years of experience and number of working hours per day apart from the questions on the level of awareness, preventive procedures undertaken and occupational hazards experienced.
RESULTS:
Significantly greater number of females experienced musculoskeletal disorders (p=0.031) and allergy to latex (p=0.004) than males. Nearly half the study population reported of sharp instrument injury while treating the patients. The most prevalent preventive measure reported by the respondents was changing gloves between the patients (98.6%) and use of face mask (97.2%). Most of the participants (94.1%) had undergone Hepatitis B or other vaccination procedures.
CONCLUSIONS:
Majority of the study population were aware of the biological hazards associated with the practice of dentistry. None of the preventive measures were observed by all the participants.
BibTeX:
@article{TadakamadlaJ2012,
  author = {Tiwari VK, Sarabahi S, Mulla Rani UK},
  title = {Occupational hazards and preventive practices among students and faculty at a private dental institution in India.},
  journal = {Stomatologija},
  year = {2012},
  volume = {14(1)},
  pages = {28-32}
}
Tiwari VK Sarabahi S, M.R.U. Heterotopic implantation of amputated digits following constriction ring syndrome: a case series. 2013 J Plast Reconstr Aesthet Surg.
Vol. 66(12), pp. 1815-7 
article DOI  
BibTeX:
@article{TiwariVK2013,
  author = {Tiwari VK, Sarabahi S, Mulla Rani UK},
  title = {Heterotopic implantation of amputated digits following constriction ring syndrome: a case series.},
  journal = {J Plast Reconstr Aesthet Surg.},
  year = {2013},
  volume = {66(12)},
  pages = {1815-7},
  doi = {http://dx.doi.org/10.1016/j.bjps.2013.06.011}
}
pre>
Tyagi AM, Srivastava K, Mansoori MN, Trivedi R, Chattopadhyay N, Singh D Estrogen deficiency induces the differentiation of IL-17 secreting Th17 cells: a new candidate in the pathogenesis of osteoporosis. 2012 PLoS One
Vol. 7(9) 
article DOI  
Abstract: Th17 cells produce IL-17, and the latter promotes bone loss in collagen-induced arthritis in mice. Blocking IL-17 action in mouse model of rheumatoid arthritis reduces disease symptoms. These observations suggest that Th17 cells may be involved in the pathogenesis of bone loss. However, the role of Th17 cell in estrogen (E2) deficiency-induced bone loss is still not very clear. We investigated the effect of E2 on Th17 differentiation in vivo and IL-17 mediated regulation of osteoclast and osteoblast differentiation. Additionally, effect of IL-17 functional block under E2 deficiency-induced bone loss was studied. In murine bone marrow cells, E2 suppressed IL-17 mediated osteoclast differentiation. IL-17 inhibited formation of mineralized nodules in osteoblasts and this effect was suppressed by E2. E2 treatment to mouse calvarial osteoblasts inhibited the IL-17-induced production of osteoclastogenic cytokines and NF-kB translocation. In ovariectomized mice, there was increase in the number of Th17 cells, transcription factors promoting Th17 cell differentiation and circulating IL-17 levels. These effects were reversed by E2 supplementation. Treatment of neutralizing IL-17 monoclonal antibody to Ovx mice mitigated the E2 deficiency-induced trabecular bone loss and reversed the decreased osteoprotegerin-to-receptor activator of nuclear factor kappa B ligand (RANKL) transcript levels in long bones, increased osteoclast differentiation from the bone marrow precursor cells and decreased osteoblast differentiation from the bone marrow stromal cells. Our findings indicate that E2 deficiency leads to increased differentiation of Th17 cells with attendant up regulation of STAT3, ROR-?t and ROR-? and downregulation of Foxp3 which antagonizes Th17 cell differentiation. Increased IL-17 production in turn induces bone loss by increasing pro-osteoclastogenic cytokines including TNF-?, IL-6 and RANKL from osteoblasts and functional block of IL-17 prevents bone loss. IL-17 thus plays a critical causal role in Ovx-induced bone loss and may be considered a potential therapeutic target in pathogenesis of post menopausal osteoporosis
BibTeX:
@article{TyagiAM2012,
  author = {Tyagi AM, Srivastava K, Mansoori MN, Trivedi R, Chattopadhyay N, Singh D.},
  title = {Estrogen deficiency induces the differentiation of IL-17 secreting Th17 cells: a new candidate in the pathogenesis of osteoporosis.},
  journal = {PLoS One},
  year = {2012},
  volume = {7(9)},
  doi = {http://dx.doi.org/10.1371/journal.pone.0044552}
}
Ushas P, Ravi V, Painatt JM, Nair PP Pneumosinus dilatans multiplex associated with hormonal imbalance. 2013 BMJ Case Rep
Vol. 26, pp. 2013:010345 
article DOI  
Abstract: Pneumosinus dilatans describes an abnormal dilation of one or more paranasal sinuses without radiological evidence of localised bone destruction, hyperostosis or mucous membrane thickening. Dilation of mastoid air cells also occurs rarely along with involvement of paranasal sinuses. This rare combination of unknown aetiology was reported in two cases in the literature and termed 'Pneumosinus Dilatans Multiplex' (PSDM). It is usually asymptomatic, and is detected incidentally on plain radiography, CT or MRI. If left untreated, it can further erode the bone leading to complications such as facial asymmetry, neurological disorders and pathological fractures. The aetiology of the condition remains obscure. Various hypotheses proposed are the presence of gas-forming microorganisms, spontaneous drainage of a mucocele, the presence of a one-way valve, dysregulation of hormonal levels leading to a disturbance of osteoblastic and osteoclastic activity. This paper describes a case of PSDM possibly secondary to hormonal disturbance.
BibTeX:
@article{UshasP2013,
  author = {Ushas P, Ravi V, Painatt JM, Nair PP.},
  title = {Pneumosinus dilatans multiplex associated with hormonal imbalance.},
  journal = {BMJ Case Rep},
  year = {2013},
  volume = {26},
  pages = {2013:010345},
  doi = {http://dx.doi.org/10.1136/bcr-2013-010345}
}
Vaish AK, Kumar N, Jain N, Agarwal A Osteogenesis imperfecta with right renal artery occlusion. 2012 BMJ Case Rep.
Vol. 7 
article DOI  
Abstract: We here report a case of osteogenesis imperfecta who presented with severe hypertension and left ventricular failure and had right renal artery occlusion. The case is very interesting as renal artery occlusion has not been reported earlier in osteogenesis imperfecta.
BibTeX:
@article{VaishAK2012,
  author = {Vaish AK, Kumar N, Jain N, Agarwal A},
  title = {Osteogenesis imperfecta with right renal artery occlusion.},
  journal = {BMJ Case Rep.},
  year = {2012},
  volume = {7},
  doi = {http://dx.doi.org/10.1136/bcr-2012-006536}
}
Vaishya R, Singh AP, Vaish A Periprosthetic subtrochanteric femoral fracture in a megaprosthesis of the knee. 2013 Chin J Traumatol.
Vol. 16(5), pp. 314-5 
article  
Abstract: We report a rare case of periprosthetic posttraumatic fracture of subtrochanteric region of femur after a megaprosthesis of the knee, done for resistant nonunion of distal femur with secondary osteoarthrosis in a 51 years old man. Treatment with a locking femoral plate was able to achieve primary union with a good result.
BibTeX:
@article{VaishyaR2013,
  author = {Vaishya R, Singh AP, Vaish A.},
  title = {Periprosthetic subtrochanteric femoral fracture in a megaprosthesis of the knee.},
  journal = {Chin J Traumatol.},
  year = {2013},
  volume = {16(5)},
  pages = {314-5}
}
Chopra A, Abdel-Nasser A Epidemiology of rheumatic musculoskeletal
disorders in the developing world
2008 Clinical Rheumatology,
Vol. 22(4), pp. 583-604 
article  
Abstract: The epidemiology of rheumatic musculoskeletal (MSK) disorders in the
developing world is much less well known than it is in the developed world. We
expect ethnicity, traditions, socioeconomics and lifestyles to have an impact,
but overall data are sparse. This report focuses on the WHO-ILAR COPCORD
(community-oriented programme for control of rheumatic diseases).
COPCORD was designed to collect community data on pain and disability in
the developing economies. Several countries in Asia-Pacific and Central South
America have completed COPCORD surveys. Despite some limitations in
methodology, COPCORD provides a fair estimate of the spectrum and extent
of rheumatic MSK disorders. We digress from a general overview to highlight
the scenario for rheumatoid arthritis, and draw a few parallels with known
statistics from the developed world. Overall, the emerging spectrum and
severity are not very different, but in the developing countries the burden of
disease, worsened by dismal rheumatology services, is likely to be staggering.
Keywords: WHO-ILAR COPCORD, rheumatic musculoskeletal disorders,
rheumatology, epidemiology, developing countries.
BibTeX:
@article{A12008,
  author = {Chopra A and Abdel-Nasser A},
  title = {Epidemiology of rheumatic musculoskeletal
disorders in the developing world}, journal = {Clinical Rheumatology,}, year = {2008}, volume = {22(4)}, pages = {583-604} }
Gupta AD, Mahalanabis D Study of hand function in a group of shoe factory
workers engaged in repetitive work
2006 J Occup Rehabil.
Vol. 16(4), pp. 675-84 
article  
Abstract: Background:
Work related hand and wrist musculoskeletal disorders are well known. The
contributing factors could be repetitive movements, forceful work and awkward
posture. It is not known how these movements affect grip or pinch strength and
other functional aspects of the hand.
Aims:
To study a group of shoe factory workers doing repetitive thumb and wrist
movements for prevalence of musculoskeletal disorders and consequence on
grip and pinch strength, two-point discrimination and perceived disability.
Methods:
39 shoe factory workers who put straps into 900 to 1000 pairs of rubber
sandals per day and 29 hospital clerks as a control group were evaluated for
musculoskeletal disorders, grip and pinch strength, two-point discrimination
and perceived disability (by questionnaire). Proportions were compared by chi
squared or Fisher Exact test and quantitative outcome by t-test or multiple
linear regressions.
Results:
Common musculoskeletal diseases of thumb/wrist were absent among shoe
factory workers as in the clerks. Increased two-point discrimination over thumb
(p=0.01, right; p=0.02, left) and a clear trend for reduced pinch strength
between thumb and index finger (p=0.06, right; p=0.07, left) were noted
compared to clerks after adjusting for years on the job. Perceived disabilities
included pain and localised dermal thickening over the thumb.
Discussion: No case of carpal tunnel syndrome or hand/wrist tendinitis was
detected among workers doing highly repetitive thumb/wrist movement. Pinch
strength decreased and two-point discrimination was adversely affected while
grip strength remained unaffected. The main perceived disabilities of pain and
skin changes over the thumb adversely affected their day-to-day life.
BibTeX:
@article{AD2006,
  author = {Gupta AD and Mahalanabis D},
  title = {Study of hand function in a group of shoe factory
workers engaged in repetitive work}, journal = {J Occup Rehabil.}, year = {2006}, volume = {16(4)}, pages = {675-84} }
Dasgupta AK, Harrison J Effects of vibration on the hand-arm system of
miners in India
1996 Occup Med (Lond).
Vol. 46(1), pp. 71-8 
article  
Abstract: Sixty-six Jackhammer drillers and 35 blasters from two mines were clinically
screened for hand-arm vibration syndrome (HAVS). The screening consisted of
questionnaire-based information, clinical examination including measurement
of phalangeal circumferences of fingers (FCT) and motor nerve conduction
(MCV) studies. In a warm environment, the prevalence of symptom comples
suggested the existence of peripheral neuropathy and musculoskeletal
abnormalities rather than any peripheral circulatory disorders. Clinical
examination revealed soft tissue wasting in the hands (26 cases), ulnar nerve
impairment (23 cases), median nerve impairment (16 cases) and Dupuytren's
contracture (4 cases). Mean motor nerve conduction velocities of 59 out of 66
drillers who volunteered for this assessment were not significantly different
from those of the 35 blasters. The results of their correlation coefficients varied
considerably for MCVs when age and years of vibration exposure underwent
regression analysis. However, comparison of MCV and FCT of 30 drillers with
30 matched blasters revealed that the mean MCV of the right median nerve in
the vibration exposed group was significantly decreased (p <0.01) and for the
mean FCT, the proximal phalans of the right index finger, left thumb and left
ring fingers were thinner in the vibration exposed group (p < 0.05).
BibTeX:
@article{AK*1996,
  author = {Dasgupta AK and Harrison J},
  title = {Effects of vibration on the hand-arm system of
miners in India}, journal = {Occup Med (Lond).}, year = {1996}, volume = {46(1)}, pages = {71-8} }
Arora A, Agarwal A, Gikas P, Mehra A Musculoskeletal training for orthopaedists and
nonorthopaedists: experiences in India
2008 Clin Orthop Relat Res.
Vol. 466(10), pp. 2350-9 
article  
Abstract: In India, health policies, services, health indices, and medical education are
improving despite the country's enormous population and limited resources.
Orthopaedic training in India should be geared to serve the predominantly rural
population (72% of total population) living in some 550,000 villages, but unless
the basic amenities improve in villages and towns, orthopaedists will remain
averse to serving in these areas. Traditional practitioners play an important role
in musculoskeletal trauma care in villages and even some town and city areas,
and hence cannot be ignored. We suggest a stratified system of orthopaedic
training for medical graduates, postgraduates, and paramedics with a welldefined
need-based curriculum, and a clear cut division of labor, terms, and
conditions to suit the stratified social and demographic structure of India. This
stratified system is intended to provide appropriate musculoskeletal trauma
care services to the rural population, reduce neglected and mismanaged
trauma, consequently avoiding subsequent orthopaedic disability, and reduce
the financial burden of managing these cases. This system also intends to
prevent overloading of teaching hospitals and apex institutes and ensure
availability of subspecialized orthopaedic services in the country at designated
centers. Traditional practitioners shall be periodically educated regarding safe
orthopaedic practices, which are anticipated to yield improved trauma care
services.
BibTeX:
@article{AroraA2008,
  author = {Arora A, Agarwal A, Gikas P and Mehra A},
  title = {Musculoskeletal training for orthopaedists and
nonorthopaedists: experiences in India}, journal = {Clin Orthop Relat Res.}, year = {2008}, volume = {466(10)}, pages = {2350-9} }
Baba AN, Paljor SD, Mir NA, Maajid S, Wani NB, Bhat AH, Bhat JA Walnut tree falls as a cause of musculoskeletal
injury--a study from a tertiary care center in
Kashmir
2010 Ulus Travma Acil Cerrahi Derg.
Vol. 16(5), pp. 464-8 
article  
Abstract: Background:
Fall from height is one of the important causes of musculoskeletal injuries.
Fall from walnut trees constitutes an important entity that leads to a significant
mortality and morbidity amongst those engaged in fruit collection. The present
study aimed to determine the prevalence of different musculoskeletal injuries
in these victims and to highlight the importance of recognizing this incident as
an occupational injury.
Methods:
A retrospective study of all patients admitted to the Orthopedic Department of
the Sher-i-Kashmir Institute of Medical Sciences (SKIMS) Medical College from
January 2003 to December 2007 was conducted. The medical records were
studied for the different types of bony injuries, associated injuries and delay in
the referral of patients.
Results:
94% of falls occurred from August to October. Of the 115 patients, 63 (54.7%)
had associated non-orthopedic injuries. Head injury was the most common
associated injury, presenting in 34 patients (29.5%). Thoracolumbar (16.5%),
calcaneum (10.5%) and distal radius (8.7%) fractures constituted the common
fractures encountered in the victims.
Conclusion:
Walnut tree injuries mostly involve young males who form the productive group
of the population. Being a seasonal injury, it puts a considerable load on the
health resources of the region over a small period of time.
BibTeX:
@article{BabaAN2010,
  author = {Baba AN, Paljor SD, Mir NA, Maajid S, Wani NB, Bhat AH, Bhat JA},
  title = {Walnut tree falls as a cause of musculoskeletal
injury--a study from a tertiary care center in
Kashmir}, journal = {Ulus Travma Acil Cerrahi Derg.}, year = {2010}, volume = {16(5)}, pages = {464-8} }
Bhanderi D, Choudhary S, Parmar L, Doshi V A study of occurrence of musculoskeletal
discomfort in computer operators
2008 Indian J Community Med.
Vol. 33(1), pp. 65-6 
article  
Abstract: Abstract not available.
BibTeX:
@article{BhanderiD2008,
  author = {Bhanderi D, Choudhary S, Parmar L and Doshi V},
  title = {A study of occurrence of musculoskeletal
discomfort in computer operators}, journal = {Indian J Community Med.}, year = {2008}, volume = {33(1)}, pages = {65-6} }
Bhattacherjee A, Bertrand JP, Meyer JP et al. Relationships of physical job tasks and living
conditions with occupational injuries in coal miners
2007 Ind Health.
Vol. 45(2), pp. 352-8 
article  
Abstract: This study assessed the relationships of job tasks and living conditions with
occupational injuries among coal miners. The sample included randomly
selected 516 underground workers. They completed a standardized selfadministred
questionnaire. The data were analyzed via logistic regression
method. The rate of injuries in the past two years was 29.8%. The job tasks
with significant crude relative risks were: power hammer, vibrating hand tools,
pneumatic tools, bent trunk, awkward work posture, heat, standing about and
walking, job tasks for trunk and upper/lower limbs, pain caused by work, and
muscular tiredness. Logistic model shows a strong relationship between the
number of job tasks (JT) and injuries (adjusted ORs vs. JT 0-1: 2.21, 95%CI
1.27-3.86 for JT 2-6 and 3.82, 2.14-6.82 for JT>or=7), and significant
ORs>or=1.71 for face work, not-good-health-status, and psychotropic drug
use. Musculoskeletal disorders and certain personality traits were also
significant in univariate analysis. Therefore job tasks and living conditions
strongly increase the injuries, and occupational physicians could help workers
to find remedial measure.
BibTeX:
@article{BhattacherjeeA2007,
  author = {Bhattacherjee A, Bertrand JP, Meyer JP, Benamghar L, Otero
Sierra C, Michaely JP, Ghosh AK, d'Houtaud A, Mur JM, Chau N;
Lorhandicap Group}, title = {Relationships of physical job tasks and living
conditions with occupational injuries in coal miners}, journal = {Ind Health.}, year = {2007}, volume = {45(2)}, pages = {352-8} }
Chandra AM, Ghosh S, Iqbal R, Sadhu N A comparative assessment of the impact of
different occupations on workers' static
musculoskeletal fitness
2007 Int J Occup Saf Ergon.
Vol. 13(3), pp. 271-8 
article  
Abstract: An ergonomic assessment of the involvement of static muscular forces like
back strength, grip strength and pinch strength in different occupations was
made. A study was conducted on 45 normal adult males (15 subjects per
group) which included video display terminal (VDT) operators, industrial
workers and safety inspectors. Their maximum back strength, handgrip
strength and pinch strength were measured with dynamometers. The observed
values of back strength were significantly lower in VDT operators while
significantly higher in safety inspectors and moderate in industrial workers. The
values of grip strength and pinch strength of all sample groups were more or
less similar. The findings clearly indicate that static muscular strength varies
significantly in different occupations. Heavy static muscular load might lead to
an accumulation of metabolic waste and toxins on the back resulting in lower
back strength in VDT operators and industrial workers.
BibTeX:
@article{ChandraAM2007,
  author = {Chandra AM, Ghosh S, Iqbal R and Sadhu N},
  title = {A comparative assessment of the impact of
different occupations on workers' static
musculoskeletal fitness}, journal = {Int J Occup Saf Ergon.}, year = {2007}, volume = {13(3)}, pages = {271-8} }
Chopra A, Lavin P, Patwardhan B, Chitre D A 32-week randomized, placebo-controlled clinical
evaluation of RA-11, an Ayurvedic drug, on
osteoarthritis of the knees
2004 J Clin Rheumatol.
Vol. 10(5), pp. 236-45 
article  
Abstract: Background:
The ancient Indian (Asian) Ayurvedic medicinal system uses herbomineral
drugs to treat arthritis. Despite centuries of use, very few have been tested by
drug trials. RA-11 (ARTREX, MENDAR), a standardized multiplant Ayurvedic
drug (Withania somnifera, Boswellia serrata, Zingiber officinale, and Cur cuma
longa) is currently used to treat arthritis.
Objective:
The objective of this study was to evaluate the efficacy and safety of RA-11 in
patients with symptomatic osteoarthritis (OA) of the knees.
Methods:
A total of 358 patients with chronic knee pain were screened free-of-cost in
"arthritis camps" in an Indian metropolis. Ninety patients with primary OA of the
knees (ACR classification; Arthritis Rheum 1986;29:1039-1049) were found
eligible (postanalgesic washout pain visual analog score [VAS] > or =40 mm in
either or both knees on body weight-bearing activities) to enroll into a
randomized, double-blind, placebo-controlled, parallel efficacy, single-center,
32-week drug trial (80% power to detect 25% difference, P = 0.05, 2-sided).
Concurrent analgesics/nonsteroidal antiinflammatory drugs and steroids in any
form were not allowed. Lifestyle and/or dietary restrictions, as per routine
Ayurveda practices, were not imposed. Pain VAS (maximum pain in each knee
recorded by the patient during the preceding 48 hours) and modified WOMAC
(Western Ontario McMaster University OA Index, Likert scale, version 3.0)
were the primary efficacy variables. The WOMAC section on "physical function
difficulty" was modified for Indian use and validated before the trial. Routine
laboratory testing was primarily done to monitor drug safety. At baseline, the
groups (active = 45, placebo = 45) were well matched for several measures
(mean pain VAS: active = 6.17; placebo = 6.5).
Results:
1) Efficacy: Compared with placebo, the mean reduction in pain VAS at week
16 (active = 2.7, placebo = 1.3) and week 32 (active = 2.8, placebo = 1.8)
in the active group was significantly (P<0.05, analysis of variance
[ANOVA]) better. Similarly, the improvement in the WOMAC scores at
week 16 and week 32 were also significantly superior (P <0.01, ANOVA)
in the active group.
2) Safety: Both the groups reported mild adverse events (AE) without any
significant difference.
3) Withdrawals: Twenty-eight patients were discontinued. None reported
drug-related toxicity. The majority failed follow up/compliance. No
differences were observed between the groups.
Conclusion:
This controlled drug trial demonstrates the potential efficacy and safety of RA-
11 in the symptomatic treatment of OA knees over 32 weeks of therapy.
BibTeX:
@article{ChopraA2004,
  author = {Chopra A, Lavin P, Patwardhan B and Chitre D},
  title = {A 32-week randomized, placebo-controlled clinical
evaluation of RA-11, an Ayurvedic drug, on
osteoarthritis of the knees}, journal = {J Clin Rheumatol.}, year = {2004}, volume = {10(5)}, pages = {236-45} }
Gangopadhyay S, Das BDas T, Ghoshal G An ergonomic study on posture-related discomfort
among preadolescent agricultural workers of West
Bengal, India
2005 Int J Occup Saf Ergon.
Vol. 11(3), pp. 315-22 
article  
Abstract: In India, particularly in West Bengal, preadolescents are primarily associated
with agricultural work in rural areas. Owing to poor socio-economic conditions,
they are compelled to carry out a considerable number of manual, rigorous
tasks in agricultural fields. The main aim of this study was to investigate
postures adopted by preadolescent agricultural workers during individual
agricultural activities and to analyze the causes of discomfort related to those
postures. Fifty male and 50 female preadolescent agricultural workers were
randomly selected and a detailed posture analysis was performed with the
Ovako Working Posture Analysis System (OWAS). It was observed that those
workers worked continuously in awkward postures during certain agricultural
activities. Consequently they suffered from discomfort in different parts of their
body. Even though they were very young, they were likely to suffer from
serious musculoskeletal disorders in the future.
BibTeX:
@article{GangopadhyayS2005,
  author = {Gangopadhyay S, Das BDas T and Ghoshal G},
  title = {An ergonomic study on posture-related discomfort
among preadolescent agricultural workers of West
Bengal, India}, journal = {Int J Occup Saf Ergon.}, year = {2005}, volume = {11(3)}, pages = {315-22} }
Gangopadhyay S, Das B, Das T, Ghoshal G, Ghosh T An ergonomics study on posture-related discomfort
and occupational-related disorders among
stonecutters of West Bengal, India
2010 Int J Occup Saf Ergon.
Vol. 16(1), pp. 69-79 
article  
Abstract: Stonecutting and setting are important tasks in a construction site. A field study
was conducted to assess occupational-related disorders and to conduct
ergonomics assessment among stonecutters. The study focused on (a) the
duration of work per day, (b) the working environment and working activities
and (c) the feeling of discomfort in different parts of the body. A detailed
posture analysis was performed with the Ovako working posture analysis
system (OWAS). It was observed that stonecutters worked continuously in
awkward postures during stonecutting and setting. Consequently, they suffered
from discomfort in different parts of their body, specifically in the lower back,
knees and shoulders, which mainly prevented them from continuing their work.
This study also revealed that stonecutters had to work in congested work areas
with a poor level of illumination. The noise level and dust particles emitted
during stonecutting activities could affect stonecutters.
BibTeX:
@article{GangopadhyayS2010,
  author = {Gangopadhyay S, Das B, Das T, Ghoshal G and Ghosh T},
  title = {An ergonomics study on posture-related discomfort
and occupational-related disorders among
stonecutters of West Bengal, India}, journal = {Int J Occup Saf Ergon.}, year = {2010}, volume = {16(1)}, pages = {69-79} }
Gangopadhyay S, Das B, Ghoshal G, Das T, Ghosh T et al. The prevalence of musculoskeletal disorders among
prawn seed collectors of Sunderbans
2008 J Hum Ergol (Tokyo).
Vol. 37(2), pp. 83-90 
article  
Abstract: In India, particularly in Sunderban of West Bengal, collection of prawn seeds is
one of the major earning resources among prawn seed collectors. They are
compelled to carry out a considerable amount of hard, manual, rigorous tasks
in the river of the Sunderban area for collecting prawn seeds. They have to
adopt some undesirable postures that may lead to the development of musculo
skeletal disorder (MSD). The main aim of the present study is to investigate the
prevalent postures adopted by the prawn seed collectors during individual
prawn seed collection and to analyze the causation of discomfort feeling
related with those postures. For this study, 21 male and 25 female prawn seed
collectors were selected randomly and a detailed posture analysis was
performed among them by means of OWAS method. It was observed that
these workers worked continuously in awkward postures during certain prawn
seed collection activity and consequently they suffered from discomfort feeling
(pain) in different parts of the body.
BibTeX:
@article{GangopadhyayS2008,
  author = {Gangopadhyay S, Das B, Ghoshal G, Das T, Ghosh T, Ganguly
R and Samanto K}, title = {The prevalence of musculoskeletal disorders among
prawn seed collectors of Sunderbans}, journal = {J Hum Ergol (Tokyo).}, year = {2008}, volume = {37(2)}, pages = {83-90} }
Gangopadhyay S, Ghosh T, Das T, Ghoshal G, Das B Effect of working posture on occurrence of musculoskeletal
disorders among the sand core making workers of West Bengal
2010 Cent Eur J Public Health.
Vol. 18(1), pp. 38-42 
article  
Abstract: The sand core making process is performed manually in West Bengal involving
a large number of workers of lowest economic strata. The core making workers
most often work for a prolonged period of time and they are forced to handle
various amounts of heavy load during the entire period of work. In this study an
attempt was made to identify the work related musculoskeletal disorders
among the sand core-making workers. Fifty male workers engaged in carbon
dioxide and chemical core making work at an unorganized sector at Baruipur,
Calcutta were randomly selected for this study. A detailed modified Nordic
questionnaire study on discomfort feeling was performed among the core
making workers. REBA method was applied to analyze the working posture.
Finally, discomfort level and risk level of the individual working postures were
calculated by the use of risk level and discomfort level scale. From the
questionnaire study it was revealed that most of the core making workers grind
often in awkward postures. The workers were affected by musculoskeletal
disorders like pain at low back (100%), hand (40%), shoulder (30%), wrist
(20%) and neck (20%). It has been also found that there is a significant (p <
0.05) correlation between discomfort level and risk level of the individual
working postures of the workers. It was concluded from the study that health of
the core-making workers was highly affected by different awkward postures
and that they suffer from posture-related musculoskeletal disorders primarily
affecting the low back region.
BibTeX:
@article{GangopadhyayS2010a,
  author = {Gangopadhyay S, Ghosh T, Das T, Ghoshal G and Das B},
  title = {Effect of working posture on occurrence of musculoskeletal
disorders among the sand core making workers of West Bengal}, journal = {Cent Eur J Public Health.}, year = {2010}, volume = {18(1)}, pages = {38-42} }
Gangopadhyay S, Ghosh T, DAS T, Ghoshal G, DAS BB Prevalence of upper limb musculo skeletal disorders
among brass metal workers in West Bengal, India
2007 Ind Health.
Vol. 45(2), pp. 365-70. 
article  
Abstract: Brass metal work is one of the oldest cottage industries in West Bengal, India.
Workers performing rigorous hand intensive jobs are likely to suffer from MSD
affecting the upper limbs. The present investigation was intended to establish
the prevalence of upper limb MSD among the brass metal workers and to
identify the causative factors behind its development. In this study, 50 male
brass metal workers (Experimental Group) and 50 male office workers
(Comparison Group) were selected. For the symptom survey, a questionnaire
on discomfort symptoms was performed. Repetitiveness of work and Hand
Grip Strength of both the groups were measured. It was revealed that upper
limb MSD was a major problem among brass metal workers, primarily involving
the hand, wrist, fingers and shoulder. Among the workers reporting subjective
discomfort, most of them felt pain, followed by tingling and numbness in their
hands. Many complained of swelling, warmth and tenderness in their wrists.
Their activities were highly repetitive and the handgrip strength of these
workers was significantly less than that of the comparison group. Based on
these findings, it appears that high repetitiveness, prolonged work activity (10.5
h of work per day with 8.4 h spent on hammering) and decreased handgrip
strength may be causative factors in the occurrence of upper limb MSD among
brass metal workers in West Bengal, India.
BibTeX:
@article{GangopadhyayS2007,
  author = {Gangopadhyay S, Ghosh T, DAS T, Ghoshal G, DAS BB},
  title = {Prevalence of upper limb musculo skeletal disorders
among brass metal workers in West Bengal, India}, journal = {Ind Health.}, year = {2007}, volume = {45(2)}, pages = {365-70.} }
Gangopadhyay S, Ray A, Das A, Das T, Ghoshal G, Banerjee P, Bagchi S A study on upper extremity cumulative trauma
disorder in different unorganised sectors of West
Bengal, India
2003 J Occup Health.
Vol. 45(6), pp. 351-7 
article  
Abstract: Cumulative trauma disorder (CTD) is a term used to describe a class of soft
tissue injuries that result due to a number of occupational activities. These
disorders commonly occur among workers who are engaged in highly repetitive
jobs involving continuous hand ertion, vibration and localized mechanical
pressure. In the present investigation, an attempt was made to evaluate the
prevalence of CTD among workers associated with strenuous hand intensive
jobs in unorganized sectors in India and to highlight the unsafe working
conditions to which these workers have been exposed for several years. For
this purpose, an experiment was performed on 25 male workers from each
group. The groups were classified into meat cutters, typists, tailors, visual
display terminal (VDT) operators & weavers. For the symptom survey, a
questionnaire and checklist method was implemented. Along with these, a
detailed time study was performed among the workers during different activities
in the total work cycle. For this study a two-tail chi-square test of independence
was applied to determine whether or not the feeling of discomfort had any
significant association with the repetitiveness of the work. From the
observations and analysis of the results, it was revealed that all the activities
are repetitive, i.e. over 50% of the work cycle of each activity involved the
respective main activity where similar kinds of motion patterns were performed.
Therefore it can be concluded that high repetitiveness, prolonged work activity
and remaining in static posture for a prolong period of time may be regarded as
the causative factors in the occurrence of CTD.
BibTeX:
@article{GangopadhyayS2003,
  author = {Gangopadhyay S, Ray A, Das A, Das T, Ghoshal G, Banerjee P
and Bagchi S.}, title = {A study on upper extremity cumulative trauma
disorder in different unorganised sectors of West
Bengal, India}, journal = {J Occup Health.}, year = {2003}, volume = {45(6)}, pages = {351-7} }
Ghosh T, Das B, Gangopadhyay S Work-related Musculoskeletal Disorder: An
Occupational Disorder of the Goldsmiths in India
2010 Indian J Community Med.
Vol. 35(2), pp. 321-25 
article  
Abstract: Background:
Gold ornament making industries are one of the widespread small-scale
industries of India. These industries belong to the unorganized sector of the
state. A large number of goldsmiths are working there for prolonged period in
cross leg posture at semi-confined workstation.
Objectives:
The aim of this study is to identify Occupational Disorder of the Goldsmiths in
India.
Materials and Methods:
In the spresent study, 120 male goldsmiths were randomly selected from the
Davangere district of Karnataka. A detailed questionnaire study on discomfort
feeling was done by the modified Nordic questionnaire, which considering the
information about work nature, job stress and discomfort feeling. The existing
workstations were assessed by the measurement of work areas. Analysis of
body posture by rapid upper limb assessment was done to evaluate the work
stress during their job.
Results:
From the analysis, it was revealed that MSDs were the major problem of the
goldsmiths. The activities of the goldsmiths were also highly repetitive.
Moreover, the questionnaire study revealed that most of the workers were
affected by occupational disorder like pain at neck (80%), shoulder (20%), wrist
(45%), and low back (75%) and also eye problem like irritation (30%) and
burning sensation (70%). They also perform their job in hazardous postures. It
was recorded that the workstations were poorly illuminated (19 Lux) in respect
to precision work. Accidents like cut and burn occurred frequently due to the
unsafe condition of the workstation.
Conclusions:
From the observation and analysis of the result it was concluded that health of
the goldsmiths were highly affected improper body posture and workload.
Twisting, bending, and over-reaching are the resultant of poorly designed
workstation. These actions force them into a non-neutral position that
increases the overall discomfort and pain at the lower back, neck, and
shoulders. Moreover, lack of proper illumination at work site also erts an
additional adverse effect on the health of the goldsmiths.
BibTeX:
@article{GhoshT2010,
  author = {Ghosh T, Das B, and Gangopadhyay S},
  title = {Work-related Musculoskeletal Disorder: An
Occupational Disorder of the Goldsmiths in India}, journal = {Indian J Community Med.}, year = {2010}, volume = {35(2)}, pages = {321-25} }
Haldiya KR, Mathur ML, Sachdeva R, Beniwal VK, Yadav SP, Singh MB, Lakshminarayana J Morbidity profile of desert population engaged in
salt production in Rajasthan
1995 J Indian Med Assoc.
Vol. 93(3), pp. 95-7, 86 
article  
Abstract: A total 2120 salt workers were examined in 8 camps organised at different salt
sites in Rajasthan. These camps were organised to find out the morbidity
conditions among salt workers and to provide preventive and curative
treatment for the ailments. The majority of salt workers who attended the
camps were males (79.0%) in comparison to females (21.0%). The majority of
workers belonged to Scheduled Castes followed by Backward Class and
Scheduled Tribes at all sites. The major morbidity disorders observed during
these camps were dermatological, respiratory, musculoskeletal, gastrointestinal
and ophthalmological in both the ses. The prevalence of hypertension
was 4.3% among both ses. The morbidity pattern in male workers was
agreeing among Sujangarh and Kuchaman and after that Pokran and Didwana
were agreeing with highest rank correlation, whereas in female workers it was
agreeing among Nawa and Sujangarh and after that Phalodi and Pokran were
agreeing with highest correlation.
BibTeX:
@article{HaldiyaKR1995,
  author = {Haldiya KR, Mathur ML, Sachdeva R, Beniwal VK, Yadav SP,
Singh MB, Lakshminarayana J.}, title = {Morbidity profile of desert population engaged in
salt production in Rajasthan}, journal = {J Indian Med Assoc.}, year = {1995}, volume = {93(3)}, pages = {95-7, 86} }
Saiyed HN, Tiwari RR Occupational health research in India 2004 Ind Health.
Vol. 42(2), pp. 141-8 
article  
Abstract: India being a developing nation is faced with traditional public health problems
like communicable diseases, malnutrition, poor environmental sanitation and
inadequate medical care. However, globalization and rapid industrial growth in
the last few years has resulted in emergence of occupational health related
issues. Agriculture (cultivators i.e. land owners + agriculture labourers) is the
main occupation in India giving employment to about 58% of the people. The
major occupational diseases/morbidity of concern in India are silicosis,
musculo-skeletal injuries, coal workers' pneumoconiosis, chronic obstructive
lung diseases, asbestosis, byssinosis, pesticide poisoning and noise induced
hearing loss. There are many agencies like National Institute of Occupational
Health, Industrial Toxicology Research Centre, Central Labour Institute, etc.
are working on researchable issues like Asbestos and asbestos related
diseases, Pesticide poisoning, Silica related diseases other than silicosis and
Musculoskeletal disorders. Still much more is to be done for improving the
occupational health research. The measures such as creation of advanced
research facilities, human resources development, creation of environmental
and occupational health cells and development of database and information
system should be taken.
BibTeX:
@article{HN2004,
  author = {Saiyed HN and Tiwari RR},
  title = {Occupational health research in India},
  journal = {Ind Health.},
  year = {2004},
  volume = {42(2)},
  pages = {141-8}
}
Jha RM, Mithal A, Malhotra N, Brown EM Pilot case-control investigation of risk factors for
hip fractures in the urban Indian population
2010 BMC Musculoskelet Disord.
Vol. 11, pp. 49 
article  
Abstract: Background:
Despite the reported high prevalence of osteoporosis in India, there have been
no previous studies examining the risk factors for hip fracture in the Indian
population.
Methods:
We carried out a case control investigation comprising 100 case subjects (57
women and 43 men) admitted with a first hip fracture into one of three hospitals
across New Delhi. The 100 controls were age and sex matched subjects who
were either healthy visitors not related to the case patients or hospital staff.
Information from all subjects was obtained through a questionnaire-based
interview.
Results:
There was a significant increase in the number of cases of hip fracture with
increasing age. There were significantly more women (57%) than men (43%).
Univariate analysis identified protective effects for increased activity, ercise,
calcium and vitamin supplements, almonds, fish, paneer (cottage cheese), curd
(plain yogurt), and milk. However, tea and other caffeinated beverages were
significant risk factors. In women, hormone/estrogen therapy appeared to have
a marginal protective effect. For all cases, decreased agility, visual impairment,
long-term medications, chronic illnesses increased the risk of hip fracture. The
multivariate analysis confirmed a protective effect of increased activity and also
showed a decrease in hip fracture risk with increasing body mass index (odds
ratio (OR) 0.024, 95% confidence interval (CI) 0.006-0.10 &amp; OR 0.81, 95%
CI 0.68-0.97 respectively). Individuals who take calcium supplements have a
decreased risk of hip fracture (OR 0.076; CI .017-0.340), as do individuals who
eat fish (OR 0.094; CI 0.020-0.431), and those who eat paneer (OR 0.152;
0.031-0.741). Tea drinkers have a higher risk of hip fracture (OR 22.8; 95% CI
3.73-139.43). Difficulty in getting up from a chair also appears to be an
important risk factor for hip fractures (OR 14.53; 95% CI 3.86-54.23).
Conclusions:
In the urban Indian population, dietary calcium, vitamin D, increased body
mass index, and higher activity levels have a significant protective effect on hip
fracture. On the other hand, caffeine intake and decreased agility increase the
risk of hip fracture. Future studies should be done in order to direct primary
preventive programs for hip fracture in India.
BibTeX:
@article{JhaRM2010,
  author = {Jha RM, Mithal A, Malhotra N and Brown EM},
  title = {Pilot case-control investigation of risk factors for
hip fractures in the urban Indian population}, journal = {BMC Musculoskelet Disord.}, year = {2010}, volume = {11}, pages = {49} }
Johnson WMS, Bertha A, Johnson P Prevalence of Upper Extremity Musculoskeletal Disorders among workers in an industrial town in Tamilnadu 2011 J Clinical and Diagnostic Research.
Vol. 5(2), pp. 187-190 
article  
Abstract: Background:
Musculo Skeletal Disorders (MSD) contribute 37% of the disease burden which
is attributable to occupational risk factors globally, resulting in substantial
disability. Despite mechanization and automation, there is an ever increasing
incidence of MSD, which has an adverse impact on the individual and the
society. Little information on the prevalence of MSD is available in South India.
Aim:
The present study was aimed primarily to evaluate the prevalence of MSD in
industrial workers and also secondarily to identify the location specific MSD, to
generate guidelines to optimize the work, to minimize the risk of injury
development and to maximize the output quality.
Material and methods:
This cross sectional pilot study included 219 subjects of age groups ranging
from 18 to 55 years, from three different industries. Questionnaires were
administered to assess the work exposure and health. The range of movement
of the joints was calculated by using a Goniometer. The postural workload was
assessed by using a RULA work sheet. A clinical examination was done to
diagnose MSD.
Results:
32.6% of the subjects suffered from MSD. The highest prevalence of MSD was
seen among pyrotechnics (44.4 %), followed by match makers (32.7%) and
litho offset printers (19.2%). An increased prevalence of symptom severity was
observed in women (36.1%) and in individuals who performed moderately
strenuous tasks (52.8%).
Conclusion:
The present study has estimated the baseline prevalence of MSD in industrial
workers, which can be effectively applied for the optimisation of the work
system to minimise the risk of injury and to maximise productivity.
Key message:
The knowledge of musculoskeletal disorders and its prevalence among
industrial workers can be effectively applied for the optimisation of the work
system to minimise the risk of injury and to maximise productivity.
BibTeX:
@article{JohnsonWMS2011,
  author = {Johnson WMS, Bertha A, Johnson P},
  title = {Prevalence of Upper Extremity Musculoskeletal Disorders among workers in an industrial town in Tamilnadu},
  journal = {J Clinical and Diagnostic Research.},
  year = {2011},
  volume = {5(2)},
  pages = {187-190}
}
Joshi TK, Menon KK, Kishore J Musculoskeletal disorders in industrial workers of
Delhi
2001 Int J Occup Environ Health.
Vol. 7(3), pp. 217-21 
article  
Abstract: To study the musculoskeletal disorders in industrial workers in Delhi, 631
workers from 60 factories representing small and medium-sized enterprises
located in Delhi were interviewed. Many (59.4%) of the workers had
musculoskeletal disorders. Tailors, those working near furnaces, cooks,
workers in buffing, checking and assembly work, and those working with
chemicals had the most joint complaints. Cervical pain was more frequent in
tailoring and packing work, whereas lumbar pain was more common in buffing,
operators working on presses, those using hand and power tools, and those
lifting heavy manual loads. Contract workers had less musculoskeletal
morbidity than regular and temporary workers. Skilled workers also had less
morbidity. Workers experiencing more job satisfaction reported fewer
musculoskeletal disorders. The high prevalence of musculoskeletal disorders in
workers needs urgent attention from the health and labor sectors. An
ergonomic approach to prevention should be considered. The current manual
load handling limits prescribed in the Indian Factory Rules potentially expose
workers to back stress. It is also inappropriate to have separate load-lifting
limits for men and women. Research is urgently required to determine the safe
load handling limits for the Indian working population based on ergonomic
principles. Until internationally acceptable safe limits are established, back pain
should be a notifiable disease in India.
BibTeX:
@article{JoshiTK2001,
  author = {Joshi TK, Menon KK and Kishore J},
  title = {Musculoskeletal disorders in industrial workers of
Delhi}, journal = {Int J Occup Environ Health.}, year = {2001}, volume = {7(3)}, pages = {217-21} }
Joshi VL, Chopra A Is There an Urban-Rural Divide? Population
Surveys of Rheumatic Musculoskeletal Disorders in
the Pune region of India Using the COPCORD
Bhigwan Model
2009 J Rheumatology
Vol. 36, pp. 3 
article  
Abstract: Objective
To estimate urban prevalence of rheumatic musculoskeletal (MSK) disorders
and compare to an earlier rural regional study.
Methods
We screened 8145 adults from a preselected urban locality in Pune, India, for
MSK pain in a cross-sectional house-to-house survey (Stage I) over 20 weeks.
The World Health Organization- International League ofAssociations for
Rheumatology (WHO-ILAR) Community Oriented Program for Control of
Rheumatic Diseases (COPCORD) Bhigwan model was used. Thirty trained
community volunteers completed Phases I and II questionnaires, concurrent
with rheumatology evaluation (Phase III). Clinical diagnosis was based on
standard diagnosis/classification criteria. Point prevalence rates from our
survey and the earlier Bhigwan village (Pune district) survey were standardized
(adjusted age-sex to India population census 2001) and are reported for
osteoarthritis (OA), rheumatoid arthritis (RA), seronegative spondyloarthritis
(SSA), and inflammatory arthritis (IA).
Results
One thousand one hundred fifty-two urban cases (65% women) were identified
(14.1%, 95% confidence interval 13.4, 14.9). The self-reported pain sites
(Phase II) were hip (0.4), knees (6.3), ankle (1.9), feet (0.7), shoulders (2),
hands (1.3), wrist (1.2), neck (1.9), upper back (1.7), low back (5.5), thigh (1.5),
calf (1.4), and sole (0.8); corresponding rural sites being hip (1.1), knees
(13.7), ankle (7), feet (1.6), shoulders (7.9), hands (6.3), wrist (6.9), neck (6.8),
upper back (8.4), low back (12.6), thigh (4.8), calf (7.1) and sole (2.2). OA
disorders, soft tissue rheumatism (STR) and illdefined aches and pains were
predominant in both surveys; < 10% reported IA. The major disorders among
urban cases were OA (4), STR (1.2), RA (0.2, ACR criteria 1988),
undifferentiated IA (0.3), SSA (0.3), and gout (0.06); corresponding rates in
Bhigwan were OA (6.3), STR (3.8), RA (0.5), undifferentiated IA (0.8), SSA
(0.3), and gout (0.1). Infections were conspicuously absent.
Conclusion
While similar in spectrum, standardized prevalence rates of self-reported pain
sites and rheumatic MSK disorders were significantly lower in the urban
(current Pune COPCORD surveys) versus rural (Bhigwan) community, and in
both communities aches and pains that are poorly understood by modern
science were predominant.
BibTeX:
@article{JoshiVL2009,
  author = {Joshi VL, Chopra A.},
  title = {Is There an Urban-Rural Divide? Population
Surveys of Rheumatic Musculoskeletal Disorders in
the Pune region of India Using the COPCORD
Bhigwan Model}, journal = {J Rheumatology}, year = {2009}, volume = {36}, pages = {3} }
Khan AA, O'Sullivan L, Gallwey TJ Effects of combined wrist deviation and forearm
rotation on discomfort score
2009 Ergonomics.
Vol. 52(3), pp. 345-61 
article  
Abstract: The aim of the study was to examine the pattern of the change in discomfort for
combined wrist deviation and forearm rotation as joint angles increased away
from neutral in a repetitive task. There were five levels of wrist deviation
(neutral, 35% and 55% of the range of motion (ROM) in radial and ulnar
deviation) and five levels of forearm rotation (neutral, 30% and 60% of the
ROM in pronation and supination). Twenty-five participants performed a
repetitive flexion task with a force of 10 N +/- 1 N at a frequency of 15 ertions
per min, with replication after 1 week for six of the participants. A visual
analogue scale was used for recording the discomfort scores. Repeated
measures analysis of covariance with the Greenhouse-Geisser correction,
where necessary, was used on transformed values of the discomfort scores.
Grip test endurance time at 50% of maximum voluntary contraction was
included as a covariate. Wrist deviation (p = 0.007) and forearm rotation (p =
0.001) were found to have significant effects. Interactions of the main factors
were not significant and nor was the covariate. Quadratic regression equations
were derived and were used to generate iso-discomfort contours, which show a
useful area of low discomfort around the central neutral zone of wrist postures,
but with steep increases in discomfort at the extreme combinations of wrist
ulnar/radial deviation with forearm pronation/supination. Discomfort equations
and contours, showing wrist and forearm postures, which are either acceptable
or potentially injurious, are useful for the design of industrial tools, machine
controls and workspaces. Reference to these can help to reduce the risk of
musculoskeletal injury associated with the tasks or tools by avoiding poor
postures with unacceptable deviations from neutral posture.
BibTeX:
@article{KhanAA2009,
  author = {Khan AA, O'Sullivan L and Gallwey TJ},
  title = {Effects of combined wrist deviation and forearm
rotation on discomfort score}, journal = {Ergonomics.}, year = {2009}, volume = {52(3)}, pages = {345-61} }
Kokane S, Tiwari RR Occupational health problems of highway
restaurant workers of Pune, India
2011 Toxicol Ind Health.  article  
Abstract: To meet the ever-increasing demand for new cuisines, the catering industry in
India is becoming more prominent day by day. According to a recent estimate,
more than two million restaurants are now dominating the present scenario of
the Indian catering industry. The health hazards in restaurants vary according
to the place that a worker is employed. The hazards among kitchen staff
include several different types of accidents such as burns from deep fryers,
slipping on grease and cuts from knives, whereas musculoskeletal disorders
are more common among waiters and helpers who usually bear load. The
present cross-sectional study included 127 workers from 15 restaurants and
dhabas situated at Pune-Mumbai high way. Interview technique followed by
clinical examination was the tool for data collection. Musculoskeletal symptoms
such as low back pain, fatigue, body ache and pain in limbs were present in 18
(14.2%) of the workers. Gastrointestinal complaints such as heartburn,
abdomen pain, stomatitis, etc. were reported by 12 (9.4%) subjects, while skinrelated
symptoms, such as itching and discoloration were reported in 12 (9.4%)
subjects. Seventy-three (57.5%) of the subjects were free from any symptoms.
BibTeX:
@article{KokaneS2011,
  author = {Kokane S, and Tiwari RR.},
  title = {Occupational health problems of highway
restaurant workers of Pune, India}, journal = {Toxicol Ind Health.}, year = {2011} }
Madan I, Reading I, Palmer KT, Coggon D Cultural differences in musculoskeletal symptoms
and disability
2008 Int J Epidemiol.
Vol. 37(5), pp. 1181-9 
article  
Abstract: Objectives:
To test the hypothesis that cultural factors such as health beliefs and
expectations have an important influence on common musculoskeletal
symptoms and associated disability, we compared prevalence rates in groups
of workers carrying out similar physical activities in different cultural settings.
Methods:
We conducted a cross-sectional survey at factories and offices in Mumbai,
India and in the UK. A questionnaire about symptoms, disability and risk factors
was administered at interview to six occupational groups: three groups of office
workers who regularly used computer keyboards (165 Indian, 67 UK of Indian
subcontinental origin and 172 UK white), and three groups of workers carrying
out repetitive manual tasks with the hands or arms (178 Indian, 73 UK of Indian
subcontinental origin and 159 UK white). Modified Cox regression was used to
calculate hazard ratios (HRs) for the prevalence of symptoms and disability by
occupational group, adjusted for differences in sex, age, mental health and job
satisfaction.
Results:
Reported occupational activities were similar in the three groups of office
workers (frequent use of keyboards) and in the three groups of manual workers
(frequent movements of the wrist or fingers, bending of the elbow, work with
the hands above shoulder height and work with the neck twisted). In
comparison with the Indian manual workers, the prevalence of back, neck and
arm pain was substantially higher in all of the other five occupational groups.
The difference was greatest for arm pain lasting >30 days in the past year in
UK white manual workers (HR 17.8, 95% CI 5.4-59.1) and UK manual workers
of Indian subcontinental origin (HR 20.5, 95% CI 5.7-73.1). Office workers in
India had lower rates of pain in the wrist and hand than office workers in the
UK. Only 1% of the Indian manual workers and 16% of the Indian office
workers had ever heard of 'RSI' or similar terms, as compared with 80% of the
UK workers.
Conclusions:
Our findings support the hypothesized impact of cultural factors on common
musculoskeletal complaints. Current controls on hazardous physical activities
in the workplace may not have the benefits that would be predicted from
observational epidemiology.
BibTeX:
@article{MadanI2008,
  author = {Madan I, Reading I, Palmer KT and Coggon D},
  title = {Cultural differences in musculoskeletal symptoms
and disability}, journal = {Int J Epidemiol.}, year = {2008}, volume = {37(5)}, pages = {1181-9} }
Mathur N, Gupta BN, Rastogi SK, Mahendra PN, Pangtey BS, Husain T, Bharti RS Socioeconomic and health status of electronics
workers employed in organized industry
1993 American J Indust Med
Vol. 23(2), pp. 321-331 
article  
Abstract: To study their socioeconomic and health status, 1,770 workers in the organised
electronics industry in India were surveyed. Mean age of the workers employed
in this industry was 32.5|6.01 years. The average per capita income/month was
INR 333, indicating a higher socioeconomic status, compared with the status of
the national population as well as compared with their counterparts in the
unorganised sectors. Respiratory symptoms and impairment rates were
significantly higher in workers exposed to soldering fumes. The high
prevalence of congested or inflamed throat was also related to chemical
exposure, especially among solderers and workers exposed to metal oxides.
The ocular symptoms and signs were also related to chemical exposure.
Musculoskeletal disorders were related to erratic ergonomic postures.
BibTeX:
@article{MathurN1993,
  author = {Mathur N, Gupta BN, Rastogi SK, Mahendra PN, Pangtey BS,
Husain T and Bharti RS}, title = {Socioeconomic and health status of electronics
workers employed in organized industry}, journal = {American J Indust Med}, year = {1993}, volume = {23(2)}, pages = {321-331} }
Medhi GK, Hazarika NC, Borah PK, Mahanta J Health problems and disability of elderly individuals
in two population groups from same geographical
location
2006 J Assoc Physicians India.
Vol. 54, pp. 539-44 
article  
Abstract: Objective:
To compare morbidity, disability (ADL-IADL disability) along with behavioral
and biological correlates of diseases and disability of two elderly population
groups (tea garden workers and urban dwellers) living in same geographical
location.
Methods:
Two hundred and ninety three and 230 elderly from urban setting and tea
garden respectively aged > 60 years were included in the study. Subjects were
physical examined and activity of daily living instrumental activity of daily living
(ADL-IADL) was assessed. Diagnosis of diseases was made on the basis of
clinical evaluation, diagnosis and/or treatment of diseases done earlier
elsewhere, available investigation reports, and electrocardiography.
Hypertension was defined according to JNC-VI classification. BMI
(weight/height2) was calculated. Logistic regression analysis was performed to
see the impact of important background characteristics on non-communicable
diseases (NCD) and disability.
Results:
Hypertension (urban--68% and tea garden--81.4%), musculoskeletal diseases
(urban--62.5% and tea garden--67.5%), COPD and other respiratory problems
(urban--30.4% and tea garden--32.2%), cataract (urban 40.3% and tea garden-
-33%), gastro-intestinal problems (urban--13% and tea garden--6.5%) were
more commonly observed health problems among community dwellings elderly
across both the groups. However in contrast to urban group, serious NCDs like
Ischaemic Heart Disease (IHD), diabetes were yet to emerge as health
problems among tea garden dwellers. Infectious morbidities, undernutrition and
disability (ADL-IADL disability) were more pronounced among tea garden
dwellers. Utilization of health service by tea garden elderly was very low in
comparison to the urban elderly. Both tea garden men and women had very
high rates of risk factors like use of non-smoked tobacco and consumption of
alcohol. On the other hand, smoking and obesity was more common in urban
group. Most morbidities and disabilities were associated with identifiable risk
factors, such as obesity, tobacco (smoked and non-smoked) and alcohol
consumption. Educational status was also found to be an important
determinant of diseases and disability of elderly population. Age showed a Jshaped
relationship with disability and morbidity. Sex difference in health status
was also detected.
Conclusion:
This study highlights the physical dimension of health problems of elderly
individuals. Social circumstances and health risk behaviours play important role
in the variation of health and functional status between the two groups. Lifestyle
modification is warranted to prevent onset of chronic diseases. To
improve quality of life, rectification of poor health status through affordable
health service for disease screening and better management of illness,
nutritional improvement and greater health awareness are necessary
particularly among low socio-economic group. Low-cost intervention like
cataract surgery could make a difference in the quality of life of elderly Indian.
BibTeX:
@article{MedhiGK2006,
  author = {Medhi GK, Hazarika NC, Borah PK and Mahanta J},
  title = {Health problems and disability of elderly individuals
in two population groups from same geographical
location}, journal = {J Assoc Physicians India.}, year = {2006}, volume = {54}, pages = {539-44} }
Mohan GM, Prasad PS, Mokkapati AK, Venkataraman G Development of risk assessment tool for foundry
workers
2008 Work.
Vol. 31(4), pp. 405-16 
article  
Abstract: Occupational ill health and work-related disorders are predominant in
manufacturing industries due to the inevitable presence of manual work even
after several waves of industrial automation and technological advancements.
Ergonomic risk factors and musculoskeletal disorders like low-back symptoms
have been noted amongst foundry workers.
Objective:
The purpose of this study was to formulate and develop a Physical Effort Index
to assess risk factor.
Scope:
The questionnaire tool applicable to foundry environment has been designed
and validated. The data recorded through survey across the foundries has
been subjected to regression analysis to correlate between proposed physical
effort index and the standard Borg's Ratings of Perceived Ertion (RPE) scale.
Results:
The physical efforts of sixty seven workers in various foundry shop floors were
assessed subjectively. The 'Job factors' and 'Work environment' were the two
major parameters considered in assessing the worker discomfort level at
workplace. A relation between Borg's RPE scale and the above two
parameters were arrived at, through regression analysis.
Conclusions:
The study demonstrates the prevalence of risk factors amongst foundry
workers and the effectiveness of the proposed index in estimating the risk
factor levels.
Relevance to the industry:
The proposed tool will assist foundry supervisors and managers to assess the
risk factors and helps in better understanding of the workplace to avoid workrelated
disorders, ensuring better output.
BibTeX:
@article{MohanGM2008,
  author = {Mohan GM, Prasad PS, Mokkapati AK and Venkataraman G},
  title = {Development of risk assessment tool for foundry
workers}, journal = {Work.}, year = {2008}, volume = {31(4)}, pages = {405-16} }
Taneja N Psychosocial factors that influence recovery in
aircrew with musculoskeletal disabilities
2010 Spine (Phila Pa 1976).
Vol. 35(11), pp. 1170-5 
article  
Abstract: Study design:
Descriptive questionnaire study
Objective:
This preliminary study was undertaken to try and develop an understanding of
the factors that may affect recovery in aircrew with musculoskeletal disabilities.
Summary of background data:
Clinical recovery from musculoskeletal disabilities is generally achieved after
the patient undergoes definitive therapy and rehabilitation. However, a
proportion of patients may continue to suffer from morbidity and pain long after
clinical and radiological finality has been reached. In these cases, psychosocial
factors may have played a contributory role. There has been no research
documenting or studying such factors in aviation and pilots in particular.
Methods:
The study was carried out at the Department of Human Engineering from 2004
to 2006. A detailed questionnaire was designed to elicit basic clinical details
and psychosocial factors at work and home.
Results:
A total of 57 male aircrew participated voluntarily in this study. Of these, 41
(71.9%) achieved normal recovery, whereas in the remaining 16 (28.1%),
recovery was considered delayed. The mean age of aircrew in the normal
recovery group (33.1 +/- 4.6 years) was slightly higher than those in the
delayed group (31.0 +/- 3.2 years). All the aircrew who had delayed recovery
had a spinal disability, whereas spinal disabilities constituted only 46.3% in the
normal recovery group. Of the spinal disabilities in aircrew with delayed
recovery, 12 had low backache. Aircraft accidents and ejection accounted for
almost one-fifth of the total disabilities (n = 11, 21.9%). The respondents
identified multiple sources of emotional support viz., friends, family, and
parents.
Conclusion:
A hypothetical model is proposed that possibly explains to some extent the role
of psychosocial factors affecting recovery in aircrew with musculoskeletal
disabilities. Further research in psychological and emotional consequences of
trauma, in particular ejection and the best means/timings to address these, is
recommended
BibTeX:
@article{N2010,
  author = {Taneja N},
  title = {Psychosocial factors that influence recovery in
aircrew with musculoskeletal disabilities}, journal = {Spine (Phila Pa 1976).}, year = {2010}, volume = {35(11)}, pages = {1170-5} }
Taneja N, Pinto LJ Diagnostic categories among 232 military aircrew
with musculoskeletal disabilities
2005 Aviat Space Environ Med.
Vol. 76(6), pp. 581-5 
article  
Abstract: Background:
Musculoskeletal disabilities are a cause for concern in aircrew as they can
critically affect return to flying duties. Analysis of the nature and cause of
musculoskeletal disabilities can provide insight to assist in developing
preventive and therapeutic intervention programs.
Methods:
The Institute of Aerospace Medicine (IAM) is responsible for centralized
evaluation of military and civil aircrew with any musculoskeletal disability. We
analyzed musculoskeletal disabilities among Indian Air Force aircrew who
were evaluated at this Institute from 2001-2003.
Results:
A total of 232 aircrew were evaluated. The majority (53.4%, n=124) came from
the fighter stream. A large proportion (30.2%, n=70) were in the age group 26
to 30 yr with an additional number (25.4%, n = 59) in the 31-35 age group.
Musculoskeletal injuries affecting the spine constituted most (48.2%, n = 121)
of the disabilities followed by upper limbs (28.2%, n = 71) and lower limbs
(19.9%, n=50), respectively. Of the spinal disabilities, degenerative disease of
the disk was the leading diagnosis (46 aircrew, 38.0%), followed by fracture of
the spine (28.1%, n=35). Road traffic accidents accounted for almost a quarter
of the injuries (23.3%, n=54).
Discussion:
These findings provide insight into the nature of musculoskeletal disabilities
among military aircrew. Implications for preventive and therapeutic strategies
are elaborated. Follow-up studies to understand the characteristics associated
with each disability have been initiated.
BibTeX:
@article{N2005,
  author = {Taneja N and Pinto LJ},
  title = {Diagnostic categories among 232 military aircrew
with musculoskeletal disabilities}, journal = {Aviat Space Environ Med.}, year = {2005}, volume = {76(6)}, pages = {581-5} }
Nag A, Vyas H, Nag PK Gender differences, work stressors and
musculoskeletal disorders in weaving industries
2010 Ind Health.
Vol. 48(3), pp. 339-48 
article  
Abstract: Study was undertaken to identify the work stressors among male and female
weavers (N=516) in powerloom and handloom and examine the association of
work stressors with the prevalence of work related musculo-skeletal disorders
(MSDs). Physical and psychosocial stresses of work, job diagnostics, hazards
of workplace, working environment and MSDs prevalence were assessed.
There is high prevalence of MSDs among weavers. Female weavers in
powerloom and handloom were more prone to developing MSDs in upper back
(OR 1.8; p<0.05 and OR 2.1; p<0.01) and lower back (OR 1.9; p<0.05 and OR
1.8; p<0.05). Male weavers were more prone to developing pain in the knee
(OR 2.9; p<0.001), and hand (OR 2.2; p<0.05). Multivariate analysis indicated
that job duration >10 yr (OR 3.7, p<0.05), manual material handling (OR 3,
p<0.05), and poor machinery safety (OR 11, p<0.05), contributed to occurrence
of MSDs amongst powerloom weavers. Among the handloom weavers, age
>25 yr (OR 3.2, p<0.05), poor machinery design (OR 2.2, p<0.01), mental
overload (OR 5.7, p<0.001), skill requirement to perform jobs (OR 20.7,
p<0.05) had significant influence in the occurrence of pain. Gender differences
exist in the prevalence of MSDs and the perception of work and psycho-social
stresses among the weavers.
BibTeX:
@article{NagA2010,
  author = {Nag A, Vyas H and Nag PK},
  title = {Gender differences, work stressors and
musculoskeletal disorders in weaving industries}, journal = {Ind Health.}, year = {2010}, volume = {48(3)}, pages = {339-48} }
Nandi SS, Dhatrak SV, Chaterjee DM, Dhumne UL Health survey in gypsum mines in India 2009 Indian J Community Med.
Vol. 34(4), pp. 343-5 
article  
Abstract: Background:
Mining is a hazardous occupation in which workers are exposed to adverse
conditions. In India, gypsum mining is mainly carried out in the state of
Rajasthan, which contributes about 99% of the total production.
Objective:
The present study was carried out in 12 different gypsum mines in Rajasthan
state to determine the health status of the miners.
Materials and methods:
One hundred and fifty workers engaged in mining activities were included in
the study and their health status was compared with that of 83 office staff of the
same mines. The health status of the employees was evaluated using a
standardized medical questionnaire and pulmonary function testing.
Statistical analysis:
The unpaired 't' test was used to determine whether there was any significant
difference between the miners and the controls and the chi-square test to
compare the prevalences of various respiratory impairments in workers with
that in controls; we also examined the differences between smokers and
nonsmokers.
Results:
Our findings show that the literacy rate is low (42%) among the miners.
Pulmonary restrictive impairment was significantly higher amongst smokers as
compared to nonsmokers in both miners and controls. Hypertension (22.6%),
diabetes (8.8%), and musculoskeletal morbidity (8%) were the common
diseases in miners.
Conclusion:
This study shows that there is high morbidity amongst miners, thus indicating
the need for regular health checkups, health education, use of personal
protective devices, and engineering measures for control of the workplace
environment.
BibTeX:
@article{NandiSS2009,
  author = {Nandi SS, Dhatrak SV, Chaterjee DM and Dhumne UL},
  title = {Health survey in gypsum mines in India},
  journal = {Indian J Community Med.},
  year = {2009},
  volume = {34(4)},
  pages = {343-5}
}
Mukhopadhyay P, Srivastava S Evaluating ergonomic risk factors in non-regulated
stone carving units of Jaipur
2010 Work.
Vol. 35(1), pp. 87-99 
article  
Abstract: Background:
Stone carving at Jaipur in Rajasthan state of India, is a traditional craft
employing a large number of local youths. As an unorganized sector problems
are many ranging from lack of benefits to occupational ergonomic issues of
Work Related Musculoskeletal Disorders(WMSDs) and injury to body parts.
Study design:
Twenty-five male workers were selected in each of the three sections of a
stone-carving unit. The focus was to identify different ergonomic risk factors
associated in this profession from the field.
Methods:
Still photography and video photography was used to record different activities.
Different types of non invasive tools like Rapid Entire Body Assessment
(REBA), Rapid Upper Limb Assessment (RULA), Occupational Repetitive
Action Index (OCRA) were used. Psychophysical measures were investigated
by Body part discomfort map, rated perceived ertion scale and visual analogue
scale. Objective measurements (heart arte and skin temperature) were
recorded with stop watch and digital thermometer.
Results:
The working heart rate after 30 minutes of work was 112.4 beats per minute
categorizing the work as moderately heavy. Postural analysis by REBA
indicated high score (13/13). Similarly postural analysis by RULA showed high
score (7/7). These indicate vulnerability of many of the postures to
musculoskeletal disorders and injury.
Conclusion:
The study indicates that majority of the activities are in the high risk category
and demands immediate ergonomic intervention in the form of tool, workstation
and process design. This could be done by involving different Non Government
Organizations (NGOs), political parties, and the Human Rights Department
both at the center and at the state level.
BibTeX:
@article{P2010,
  author = {Mukhopadhyay P and Srivastava S},
  title = {Evaluating ergonomic risk factors in non-regulated
stone carving units of Jaipur}, journal = {Work.}, year = {2010}, volume = {35(1)}, pages = {87-99} }
Pradhan CK, Thakur S, Chowdhury AR Physiological and subjective assessment of food
grain handling workers in West Godavari district,
India
2007 Ind Health.
Vol. 45(1), pp. 165-9 
article  
Abstract: There are many rice mills and food grain depots where a large number of
workers are engaged for processing paddy and rice, storage and distribution.
Lifting, carrying and depositing sacs of food grain are the major jobs carried out
by these workers. The present study was undertaken to evaluate the workers
with respect to their nutritional status, workload, energy expenditure and
musculoskeletal pain or discomfort resulting out of work practice. Average peak
heart rate of the depot and rice mill workers suggested the workload as
moderate to very heavy. Their average energy expenditure values also
indicated the workload as moderate to heavy. Subjective assessment of the
workers showed the workload as heavy for 60.7% depot workers and 23.1%
rice mill workers. Musculoskeletal pain or discomfort was maximally reported in
knee by 59% depot workers whereas low back and knee was reported by
61.5% rice mill workers. Besides the weight of the sac, awkward postures like
bending and twisting of trunk adopted frequently causes the problem. Further
studies and rationalization of work method may improve the health and safety
of the workers
BibTeX:
@article{PradhanCK2007,
  author = {Pradhan CK, Thakur S and Chowdhury AR},
  title = {Physiological and subjective assessment of food
grain handling workers in West Godavari district,
India}, journal = {Ind Health.}, year = {2007}, volume = {45(1)}, pages = {165-9} }
Malkin R Health Hazard Evaluation Report: 2003 HETA 99-0106-2838, Indian Health Service. Govt Reports
Announcements & Index (GRA&I),
Vol. 03 
article  
Abstract: On February 16, 1999, the National Institute for Occupational Safety and
Health (NIOSH) received a request for a health hazard evaluation (HHE) from
the management of the Dental Branch of the Indian Health Service (IHS).
Management was concerned about musculoskeletal disorders, particularly
neck disorders, among the IHS dental clinic staff, and wanted to know the
extent of the problem and what equipment and tasks were associated with
these disorders.
BibTeX:
@article{R2003,
  author = {Malkin R},
  title = {Health Hazard Evaluation Report:},
  journal = {HETA 99-0106-2838, Indian Health Service. Govt Reports
Announcements & Index (GRA&I),}, year = {2003}, volume = {03} }
Ramprasad M, Alias J, Raghuveer AK Effect of backpack weight on postural angles in
preadolescent children
2010 Indian Pediatr.
Vol. 47(7), pp. 575-80 
article  
Abstract: Background:
Carrying heavy backpacks could cause a wide spectrum of pain related
musculoskeletal disorders and postural dysfunctions.
Objective:
To determine the changes in various postural angles with different backpack
weights in preadolescent children.
Design:
Cross-sectional
Participants:
Healthy male school-children (n=200), mean (SD) age: 12.5 (0.5) years, from
high schools in Mangalore, India.
Measurements:
Bodyweight and height were measured using a forceplate and stadiometer,
respectively. From the weight recorded, 5%, 10%, 15%, 20%, and 25% of the
bodyweight were calculated and implemented as their respective backpack
loads. The Image Tool version 3.0, digitizing software was used for analyzing
photographs to determine craniovertebral (CV), head on neck (HON), head and
neck on trunk (HNOT), trunk and lower limb angles. Postural angles were
compared with no backpack and with backpacks weighing 5% to 25% of the
subject's bodyweight.
Results:
The CV angle changed significantly after 15% of backpack load (P <0.05). The
HON and HNOT angles changed significantly after 10% of backpack load (P
<0.05). The trunk and lower limb angle also changed significantly after 5% of
backpack load (P <0.05).
Conclusions:
Carrying a backpack weighing 15% of body weight change all the postural
angles in preadolescent children.
BibTeX:
@article{RamprasadM2010,
  author = {Ramprasad M, Alias J and Raghuveer AK},
  title = {Effect of backpack weight on postural angles in
preadolescent children}, journal = {Indian Pediatr.}, year = {2010}, volume = {47(7)}, pages = {575-80} }
Roy S, Dasgupta A A study on health status of women engaged in a
home-based "Papad-making" industry in a slum
area of Kolkata
2008 Indian J Occup Environ Med.
Vol. 12(1), pp. 33-6 
article  
Abstract: Background:
The 'papad-making' industries of India have provided ample opportunity of
employment for the women workers of low socio-economic class although their
problems are not much explored. In this study an attempt had been made for
the same.
Aims:
1. To find out the health status of the women.
2. To find out the factors, in the working conditions, influencing their health
status.
3. To assess their felt needs.
Settings:
A slum area of Kolkata.
Design:
A cross-sectional, descriptive type of observational study.
Methods and materials:
The slum was chosen by random sampling method. Following this, complete
enumeration method was adopted. Data were collected by interview and
clinical examination of the women engaged in this occupation with a
predesigned and pretested schedule.
Statistical analysis:
Proportions and Chi-square test.
Results:
77.5% were in the reproductive age group and none were below 14 years.
Most of them belonged to poor socioeconomic status. Sixty per cent were in
this occupation for more than 10 years and they spent 5 hours for this work
daily over and above their household job. Musculoskeletal problem was their
commonest health problem. Pallor, angular stomatitis, pedal edema, chronic
energy deficiency were found on examination. Personal hygienic measures
taken were far from satisfactory. A focus group discussion revealed their health
and family problems, dissatisfaction about their working conditions and wage.
Other needs identified were home visits for their health care, free medicines
and health education.
Conclusion:
Need exists for a participatory occupational health programme for this working
population.
BibTeX:
@article{RoyS2008,
  author = {Roy S, Dasgupta A},
  title = {A study on health status of women engaged in a
home-based "Papad-making" industry in a slum
area of Kolkata}, journal = {Indian J Occup Environ Med.}, year = {2008}, volume = {12(1)}, pages = {33-6} }
Tiwari RR Occupational health hazards in sewage and sanitary
workers
2008 Indian J Occup Environ Med.
Vol. 12(3), pp. 112-5 
article  
Abstract: An estimated 1.2 million scavengers in the country are involved in the
sanitation of our surroundings. The working conditions of these sanitary
workers have remained virtually unchanged for over a century. Apart from the
social atrocities that these workers face, they are exposed to certain health
problems by virtue of their occupation. These health hazards include exposure
to harmful gases such as methane and hydrogen sulfide, cardiovascular
degeneration, musculoskeletal disorders like osteoarthritic changes and
intervertebral disc herniation, infections like hepatitis, leptospirosis and
helicobacter, skin problems, respiratory system problems and altered
pulmonary function parameters. This can be prevented through engineering,
medical and legislative measures. While the engineering measures will help in
protecting against exposures, the medical measures will help in early detection
of the effects of these exposures. This can be partly achieved by developing an
effective occupational health service for this group of workers. Also, regular
awareness programs should be conducted to impart education regarding safer
work procedures and use of personal protective devices.
BibTeX:
@article{RR2008,
  author = {Tiwari RR},
  title = {Occupational health hazards in sewage and sanitary
workers}, journal = {Indian J Occup Environ Med.}, year = {2008}, volume = {12(3)}, pages = {112-5} }
Haque S, Khan AA Effects of ulnar deviation of the wrist combined
with flexion/extension on the maximum voluntary
contraction of grip
2009 J Hum Ergol (Tokyo).
Vol. 38(1), pp. 1-9 
article  
Abstract: Work-related musculoskeletal disorders (WMSDs) is related with the frequency
of ertion for repetitive tasks requiring heavy load. Different researchers have
reported that a poor posture is very much responsible for WMSD if combined
with increased load and/or frequency. In the assembly tasks in different
industries involve the gripping very commonly. Therefore in the present study it
was tried to find the effect of a wrist posture on grip strength. For design of
experiment, subjects, flexion/extension and ulnar deviation of the wrist were
taken as independent variables and the dependent variable was maximum
voluntary contraction (MVC) of grip. The results showed that the effect of
flexion/extension angle, ulnar angle and the subject on MVC grip were highly
significant (i.e., p<0.001, 0.001 and 0.002 respectively). The two-way
interaction effect of flexion/extension angle of the wrist and the subject on MVC
grip was also found significant at p<0.001. The other interaction effects were
not found significant. MVC grip was found maximum at the neutral wrist
posture.
BibTeX:
@article{S2009,
  author = {Haque S and Khan AA},
  title = {Effects of ulnar deviation of the wrist combined
with flexion/extension on the maximum voluntary
contraction of grip}, journal = {J Hum Ergol (Tokyo).}, year = {2009}, volume = {38(1)}, pages = {1-9} }
Kumar S, Mandal MK Task-specific motor performance and
musculoskeletal response in self-classified right
handers
2003 Int J Neurosci.
Vol. 113(11), pp. 1487-95 
article  
Abstract: We examined the difference between the left and right hand motor
performance (in terms of erg produced) of self-classified right handers (15
men, 15 women) for power (task involving muscle force) and skilled (task
involving precision and eye hand coordination) tasks. Musculoskeletal
response during task performance was measured by electromyogram to test
the hypothesis that performance with the nondominant hand would trigger
more generalized muscle tension. The difference between the left and right
hand performance of men was nonsignificant for power task; for women, right
hand performance was significantly superior than left for such task. Men
excelled in power and women excelled in skilled tasks relative to their
counterparts. Generalized muscle tension was significantly more during the left
than the right hand performance for power but not for skilled tasks.
BibTeX:
@article{S2003,
  author = {Kumar S and Mandal MK},
  title = {Task-specific motor performance and
musculoskeletal response in self-classified right
handers}, journal = {Int J Neurosci.}, year = {2003}, volume = {113(11)}, pages = {1487-95} }
Saha R, Dey NC, Samanta A, Biswas R A comparison of physiological strain of carriers in
underground manual coal mines in India
2008 Int J Occup Environ Health.
Vol. 14(3), pp. 210-7 
article  
Abstract: Thirty-nine healthy carriers (23-57 years of age) were investigated in
underground manual coal mines in West Bengal, India during two different
work spells of a single work shift. We compared physiological strain of workers
<40 and > or =40 years of age. For both groups, mean heart rate was 124-133
beats/min, with a mean corresponding relative cardiac cost of 50-66%.
Maximum aerobic capacities were estimated indirectly, following a standard
step test protocol. Average oxygen consumption was 1.07-1.1 l/min, with an
energy expenditure of 5.35-5.5 kcal/min among both age groups. Acceptable
levels of physiological strain were well encroached, and older workers faced
the maximum burden. The tasks studied were heavy to very heavy in nature.
The weight of load carriage at a spontaneously chosen speed and the
prevailing environmental conditions merit serious attention. There is extreme
need of ergonomic interventions in reducing the postural load and
musculoskeletal discomforts in this population
BibTeX:
@article{SahaR2008,
  author = {Saha R, Dey NC, Samanta A and Biswas R},
  title = {A comparison of physiological strain of carriers in
underground manual coal mines in India}, journal = {Int J Occup Environ Health.}, year = {2008}, volume = {14(3)}, pages = {210-7} }
Sharan D, Parijat P, Sasidharan AP, Ranganathan R, Mohandoss M, Jose J Workstyle Risk Factors for Work Related
Musculoskeletal Symptoms Among Computer
Professionals in India
2011 J Occup Rehabil.  article  
Abstract: Introduction Work-related musculoskeletal disorders are common in computer
professionals. Work style may be one of the risk factors in the development of
musculoskeletal discomfort. The objective of this retrospective study was to
examine the prevalence of adverse workstyle in computer professionals from
India and to evaluate if work style factors were predictors of pain and loss of
productivity. Methods Office workers from various information technology (IT)
companies in India responded to the short-form work style questionnaire and
pain questionnaire. Correlation analyses were conducted to examine the
associations between different variables followed by a multivariate logistic
regression to understand the unique predictors of pain and loss of productivity.
Results 4,500 participants responded to the work style and pain questionnaire.22% of participants were reported to have a high risk of an adverse work style.
63% of participants reported pain symptoms. Social reactivity, lack of breaks,
and deadlines/pressure subscales of work style questionnaire were
significantly correlated with pain and loss of productivity. Regression analyses
revealed that work style factors and duration of computer use per day were
significant predictors of pain. Conclusion Work style seems to be a mediating
factor for musculoskeletal pain, discomfort, and loss of productivity. Based on
the study findings, it is recommended that intervention efforts directed towards
prevention of musculoskeletal disorders should focus on psychosocial work
factors such adverse work style in addition to biomechanical risk factors.
BibTeX:
@article{SharanD2011,
  author = {Sharan D, Parijat P, Sasidharan AP, Ranganathan R,
Mohandoss M, Jose J.}, title = {Workstyle Risk Factors for Work Related
Musculoskeletal Symptoms Among Computer
Professionals in India}, journal = {J Occup Rehabil.}, year = {2011} }
Silvian SP, Maiya A, Resmi AT, Page T Antecedents of work related musculoskeletal
disorders in software professionals
2011 Int J Enterprise Network Manage
Vol. 4(3), pp. 247-260 
article  
Abstract: In this paper, the present Indian burden of work related musculoskeletal
disorders are studied. Adult musculoskeletal disorders (MSD) such as neck
and low back pain have been widely reported as being of significant health and
economic concern due to increased globalisation and industrial advancements.
This study is an attempt to find whether these disorders are also prevalent
amongst Indian software professionals. The paper also reveals the role of
gender differences in MSD. Neck pain is found to be the most prevalent pain.
Posture, body fatigue, hours of computer usage and lack of ergonomic
knowledge etc. are found to be causal factors determining work related MSD. A
total of 355 software professionals were studied and the research draws
conclusion that it is important to have conscientisation about the changing
world and the increased need for ergonomics interventions in today's work
places.
BibTeX:
@article{SilvianSP2011,
  author = {Silvian SP, Maiya A, Resmi AT, Page T},
  title = {Antecedents of work related musculoskeletal
disorders in software professionals}, journal = {Int J Enterprise Network Manage}, year = {2011}, volume = {4(3)}, pages = {247-260} }
Badjate SJ, Cariappa KM Scapholunate dislocation: a rare occupational
hazard
2007 Br J Oral Maxillofac Surg.
Vol. 45(3), pp. 236-7 
article  
Abstract: Dentists and their assistants are at risk of physical injuries during dental
operations. The most common injuries are musculoskeletal. The need to work
in a fid working position using continuous repetitive movements can predispose
dentists to wrist ache, lower backache, and neckache. We encountered a rare
case of scapholunate dislocation with ligamentous injury, an unusual
complication of extraction of teeth.
BibTeX:
@article{SJ2007,
  author = {Badjate SJ and Cariappa KM},
  title = {Scapholunate dislocation: a rare occupational
hazard}, journal = {Br J Oral Maxillofac Surg.}, year = {2007}, volume = {45(3)}, pages = {236-7} }
Kar SK, Dhara PC An evaluation of musculoskeletal disorder and
socioeconomic status of farmers in West Bangal,
India
2007 Nepal Medical College Journal.
Vol. 9(4), pp. 245-9 
article  
Abstract: Rice cultivation contains several tasks and workers were compelled to adopt
some harmful and awkward posture during performing those tasks. These type
repetitive jobs may be related to occupational health hazards like
musculoskeletal disorder (MSD). In the present investigation different MSD
related problems of the workers have been assessed and also identify the
socioeconomic status of the farmers considering the issues of community
health development. In this connection a simple and easily applicable
questionnaire technique has been apply in the agricultural field during
performing rice cultivation tasks. The results showed that a large number of
workers could not complete their primary education (33.0% to 43.0%) and
remained below the poverty line (91.3%). From the MSD assessment lower
back problem was prevalent (48.8%) among the workers when all rice
cultivation tasks were consider together, but it was extremely prevalent in
reaping job (92.0%) and transplantation job (84.0%). It was concluded that
MSD among the workers might be related to the stressful work posture, long
duration jobs, nature of jobs and use of ill-fitted hand tools. So, some free-hand
ercise, proper work-rest scheduled and awareness program may be helpful for
reducing the MSD and proper handling of hand tools.
BibTeX:
@article{SK2007,
  author = {Kar SK and Dhara PC},
  title = {An evaluation of musculoskeletal disorder and
socioeconomic status of farmers in West Bangal,
India}, journal = {Nepal Medical College Journal.}, year = {2007}, volume = {9(4)}, pages = {245-9} }
Srilatha G, Maiya A, Bhat V , Sathiakumar N Prevalence of Work-Related Wrist and Hand
Musculoskeletal Disorders (WMSD) among
Computer Users, Karnataka State, India
2011 J Clinical and Diagnostic Research.
Vol. 5(3), pp. 605-607 
article  
Abstract: Background: Work-related musculoskeletal (WMSD) disorders of the wrist and
hand have been reported among computer users. Data on estimates of
prevalence of computer users in India are limited.
Aim: To Find prevalence of self-reported WMSD of the wrist and hand among
computer users.
Method: A survey using questionnaire distributed to 783 computer users,
employed at two workplaces in Karnataka, India.
Result: Prevalence of self-reported WMSD of the wrist and hand was 58%.
Women were more to report symptoms than men (69% vs. 53%). Computer
users between 21 to 30 years of age were more to report symptoms than those
between 40 to 55 years (76% vs. 9 %).
Conclusion: The prevalence of WMSD of wrist and hand is high and
dependent on gender and age. There is a need to develop specific strategies in
workplace to reduce the occurrence of WMSD of the wrist and hand.
BibTeX:
@article{SrilathaG2011,
  author = {Srilatha G, Maiya A, Bhat V , Sathiakumar N},
  title = {Prevalence of Work-Related Wrist and Hand
Musculoskeletal Disorders (WMSD) among
Computer Users, Karnataka State, India}, journal = {J Clinical and Diagnostic Research.}, year = {2011}, volume = {5(3)}, pages = {605-607} }
Srivastava AK, Gupta BN, Bihari V, Gaur JS, Mathur N, Awasthi VK Clinical studies of employees in a sheet-forming
process at a paper mill
1992 Vet Hum Toxicol.
Vol. 34(6), pp. 525-7 
article  
Abstract: Formaldehyde resins are used to improve the wet strength of paper. During the
sheet-forming process of paper manufacture, formaldehyde fumes are
liberated. Twenty-two male subjects having such exposures in a paper mill and
27 unexposed subjects were clinically evaluated to determine the effect of low
level formaldehyde exposure in a tropical country. The workers were exposed
to 0.03 mg formaldehyde/m3 air as an 8-h TWA. Formic acid excretion in urine
was 37.2 +/- 18.9 and 20.3 +/- 4.2 ug/L among the exposed and the unexposed
subjects, respectively. Significantly more respiratory problems (31.8%) were
observed among the exposed subjects as compared to controls. Complaints
pertaining to gastrointestinal, musculoskeletal and cardiovascular systems
were also more frequent in exposed subjects. In spite of formaldehyde
concentrations being well within the prescribed ACGIH limits of 1 ppm, the high
rates of sickness emphasise the need for detailed studies on formaldehydeexposed
subjects in tropical countries.
BibTeX:
@article{SrivastavaAK1992,
  author = {Srivastava AK, Gupta BN, Bihari V, Gaur JS, Mathur N, Awasthi
VK.}, title = {Clinical studies of employees in a sheet-forming
process at a paper mill}, journal = {Vet Hum Toxicol.}, year = {1992}, volume = {34(6)}, pages = {525-7} }
Amell T, Kumar S Work-related musculoskeletal disorders: design as a
prevention strategy. A review
2001 J Occup Rehabil.
Vol. 11(4), pp. 255-65. 
article  
Abstract: Work-related musculoskeletal disorders are of serious concern to many
organizations, including industry, insurance, and health care. They are also of
immediate concern to the workers and their families who are adversely affected
by these disorders. Work-related musculoskeletal disorders are a substantial
source of economic drain to these organizations. Sources of this drain include
economic losses incurred from lost or decreased productivity as well as
medical treatment and indemnity costs. Therefore, it is within the best interest
of these organizations to prevent work-related musculoskeletal disorders from
occurring, before they manifest into serious issues of medical, social, and
economic concern. The purpose of this paper is to review the concept of workrelated
musculoskeletal disorders and discuss the basis of their prevention as
a primary means of occupational injury and illness management. The principal
contributory role of ergonomics/human factors is presented as a viable means
of prevention and an important contributor to the comprehensive management
of these disorders.
BibTeX:
@article{T2001,
  author = {Amell T and Kumar S},
  title = {Work-related musculoskeletal disorders: design as a
prevention strategy. A review}, journal = {J Occup Rehabil.}, year = {2001}, volume = {11(4)}, pages = {255-65.} }
Talwar R, Kapoor R, Puri K, Bansal K, Singh S A study of visual and musculoskeletal health
disorders among computer professionals in NCR
Delhi
2009 Indian J Community Med.
Vol. 34(4), pp. 326-8 
article  
Abstract: Objective:
To study the prevalence of health disorders among computer professionals and
its association with working environment conditions.
Study design:
Cross sectional.
Materials and methods:
A sample size of 200 computer professionals, from Delhi and NCR which
included software developers, call centre workers, and data entry workers.
Result:
The prevalence of visual problems in the study group was 76% (152/200), and
musculoskeletal problems were reported by 76.5% (153/200). It was found that
there was a gradual increase in visual complaints as the number of hours spent
for working on computers daily increased and the same relation was found to
be true for musculoskeletal problems as well. Visual problems were less in
persons using antiglare screen, and those with adequate lighting in the room.
Musculoskeletal problems were found to be significantly lesser among those
using cushioned chairs and soft keypad.
Conclusion:
A significant proportion of the computer professionals were found to be having
health problems and this denotes that the occupational health of the people
working in the computer field needs to be emphasized as a field of concern in
occupational health.
BibTeX:
@article{TalwarR2009,
  author = {Talwar R, Kapoor R, Puri K, Bansal K and Singh S},
  title = {A study of visual and musculoskeletal health
disorders among computer professionals in NCR
Delhi}, journal = {Indian J Community Med.}, year = {2009}, volume = {34(4)}, pages = {326-8} }
Telles S, Dash M, Naveen KV Effect of yoga on musculoskeletal discomfort and
motor functions in professional computer users
2009 Work.
Vol. 33(3), pp. 297-306 
article  
Abstract: The self-rated musculoskeletal discomfort, hand grip strength, tapping speed,
and low back and hamstring flexibility (based on a sit and reach task) were
assessed in 291 professional computer users. They were then randomized as
Yoga (YG; n=146) and Wait-list control (WL; n=145) groups. Follow-up
assessments for both groups were after 60 days during which the YG group
practiced yoga for 60 minutes daily, for 5 days in a week. The WL group spent
the same time in their usual recreational activities. At the end of 60 days, the
YG group (n=62) showed a significant decrease in the frequency, intensity and
degree of interference due to musculoskeletal discomfort, an increase in
bilateral hand grip strength, the right hand tapping speed, and low back and
hamstring flexibility (repeated measures ANOVA and post hoc analysis with
Bonferroni adjustment). In contrast, the WL group (n=56) showed an increase
in musculoskeletal discomfort and a decrease in left hand tapping speed. The
results suggest that yoga practice is a useful addition to the routine of
professional computer users.
BibTeX:
@article{TellesS2009,
  author = {Telles S, Dash M and Naveen KV},
  title = {Effect of yoga on musculoskeletal discomfort and
motor functions in professional computer users}, journal = {Work.}, year = {2009}, volume = {33(3)}, pages = {297-306} }
Veturi SM, Lakshmi BK, Ganguli AK, Chakrabarti AK The impact and feasibility of international/national
standards in the prevention of musculoskeletal
injuries in developing countries
1987 Ergonomics.
Vol. 30(2), pp. 405-10 
article  
Abstract: Abstract not available.
BibTeX:
@article{VeturiSM1987,
  author = {Veturi SM, Lakshmi BK, Ganguli AK, Chakrabarti AK},
  title = {The impact and feasibility of international/national
standards in the prevention of musculoskeletal
injuries in developing countries}, journal = {Ergonomics.}, year = {1987}, volume = {30(2)}, pages = {405-10} }
(Last Updated Upto:2014)